What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Phosphorylation
The scientist’s investigation covers issues in Cell biology, Biochemistry, Insulin receptor, Phosphatidylinositol and Endosome.
His Cell biology study combines topics from a wide range of disciplines, such as Endocytic cycle and EEA1.
His study in Insulin receptor concentrates on IRS2 and Insulin receptor substrate.
The IRS2 study combines topics in areas such as Insulin Receptor Substrate Proteins, Tyrosine kinase and GRB10.
His Phosphatidylinositol research entails a greater understanding of Kinase.
The study incorporates disciplines such as Microtubule, Membrane transport, GTPase and Membrane docking in addition to Endosome.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. (1389 citations)
- Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation. (875 citations)
What are the main themes of his work throughout his whole career to date?
Jonathan M. Backer spends much of his time researching Cell biology, Biochemistry, Insulin receptor, Kinase and Phosphatidylinositol.
His Cell biology research includes themes of Receptor and Endocytic cycle.
In his work, IRS1 is strongly intertwined with Insulin Receptor Substrate Proteins, which is a subfield of Biochemistry.
His Insulin receptor research integrates issues from Autophosphorylation and Tyrosine phosphorylation.
His biological study deals with issues like Molecular biology, which deal with fields such as Wortmannin, Mutant, Cell migration, Motility and Epidermal growth factor.
Phosphatidylinositol 3-Kinases is the focus of his Phosphatidylinositol research.
He most often published in these fields:
- Cell biology (56.97%)
- Biochemistry (36.36%)
- Insulin receptor (23.03%)
What were the highlights of his more recent work (between 2011-2021)?
- Cell biology (56.97%)
- Receptor tyrosine kinase (10.91%)
- PI3K/AKT/mTOR pathway (12.12%)
In recent papers he was focusing on the following fields of study:
Jonathan M. Backer focuses on Cell biology, Receptor tyrosine kinase, PI3K/AKT/mTOR pathway, G protein-coupled receptor and Signal transduction.
His Biochemistry research extends to the thematically linked field of Cell biology.
Within one scientific family, Jonathan M. Backer focuses on topics pertaining to Integrin under Receptor tyrosine kinase, and may sometimes address concerns connected to Haptotaxis.
The concepts of his PI3K/AKT/mTOR pathway study are interwoven with issues in Carcinogenesis, Insulin and Kinase.
His G protein-coupled receptor research is multidisciplinary, relying on both Heterotrimeric G protein, G protein, Protein subunit and GTPase.
His work deals with themes such as Transport protein, Cancer research and BAG3, which intersect with Signal transduction.
Between 2011 and 2021, his most popular works were:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34 (100 citations)
- G protein-coupled receptor-mediated activation of p110b by Gβγ is required for cellular transformation and invasiveness (96 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Signal transduction
His scientific interests lie mostly in Cell biology, Signal transduction, Chaperone-mediated autophagy, Computational biology and Autolysosome.
As part of his studies on Cell biology, Jonathan M. Backer frequently links adjacent subjects like Insulin.
The various areas that Jonathan M. Backer examines in his Signal transduction study include Cancer research, Protein subunit and BAG3.
His Chaperone-mediated autophagy study integrates concerns from other disciplines, such as BECN1 and Multicellular organism.
His studies in Computational biology integrate themes in fields like MAP1LC3B, Sequestosome 1, Autophagosome and Physiology.
Phagosome is a subfield of Biochemistry that Jonathan M. Backer tackles.
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