Jonathan M. Backer

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  10661
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

  Xiao Jian Sun;P. Rothenberg;P. Rothenberg;C. R. Kahn;J. M. Backer

  2034
  Citations

• Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.

  J M Backer;M G Myers;S E Shoelson;D J Chin

  1263
  Citations

• Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

  Yun Zhong;Qing Jun Wang;Qing Jun Wang;Xianting Li;Ying Yan

  1101
  Citations

• Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase

  Takahiro Nobukuni;Manel Joaquin;Manel Joaquin;Marta Roccio;Stephen G. Dann

  944
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• The regulation and function of Class III PI3Ks: novel roles for Vps34

  Jonathan M. Backer

  889
  Citations

• The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc : implications for insulin control of ras signalling

  E Y Skolnik;C H Lee;A Batzer;L M Vicentini

  868
  Citations

• Phosphatidylinositol-3-OH kinases are Rab5 effectors.

  S Christoforidis;M Miaczynska;M Miaczynska;K Ashman;M Wilm

  794
  Citations

• Regulation of the p85/p110 Phosphatidylinositol 3′-Kinase: Stabilization and Inhibition of the p110α Catalytic Subunit by the p85 Regulatory Subunit

  Jinghua Yu;Yitao Zhang;James McIlroy;Tamara Rordorf-Nikolic

  737
  Citations

• Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

  Rutilio A. Fratti;Jonathan M. Backer;Jean Gruenberg;Silvia Corvera

  698
  Citations

• hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.

  Maya P. Byfield;James T. Murray;Jonathan M. Backer

  658
  Citations

• Rab5 regulates motility of early endosomes on microtubules

  Erik Nielsen;Fedor Severin;Jonathan M. Backer;Anthony A. Hyman

  656
  Citations

• IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

  Martin G. Myers;Jonathan M. Backer;Xiao Jian Sun;Steven Shoelson

  648
  Citations

• Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

  Otilia V. Vieira;Otilia V. Vieira;Roberto J. Botelho;Lucia Rameh;Saskia M. Brachmann;Saskia M. Brachmann

  643
  Citations

• Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

  Morris F. White;James N. Livingston;Jonathan M. Backer;Vilma Lauris

  512
  Citations

• Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit.

  Nabil Miled;Ying Yan;Wai Ching Hon;Olga Perisic

  489
  Citations

• IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

  Martin G. Myers;Xiao Jian Sun;Bentley Cheatham;Bozena R. Jachna

  417
  Citations

• Expression and function of IRS-1 in insulin signal transmission.

  Xiao-Jian Sun;M. Miralpeix;M. G. Myers;E. M. Glasheen

  415
  Citations