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Biology and Biochemistry

D-Index
72
Citations
23614
World Ranking
6181
National Ranking
2908

Overview

Jeffrey E. Segall is affiliated with the Albert Einstein College of Medicine in the United States. Their research centers on topics within Biochemistry, Genetics and Molecular Biology, and Medicine, with specialized focus on Cell Biology, Oncology, Biomedical Engineering, Molecular Biology, and Genetics.

The scientist's work largely explores areas related to Cellular Mechanics and Interactions, Cancer Cells and Metastasis, 3D Printing in Biomedical Research, Proteoglycans and glycosaminoglycans research, Cancer-related Molecular Pathways, Glioma Diagnosis and Treatment, and Single-cell and spatial transcriptomics.

Selected recent publications by Jeffrey E. Segall include the following:

  • Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination, 2021, Nature Communications
  • Tumor spheroids under perfusion within a 3D microfluidic platform reveal critical roles of cell-cell adhesion in tumor invasion, 2020, Scientific Reports
  • Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma, 2023, Clinical Cancer Research
  • Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia, 2020, Science Advances
  • Palbociclib Renders Human Papilloma Virus-Negative Head and Neck Squamous Cell Carcinoma Vulnerable to the Senolytic Agent Navitoclax, 2021, Molecular Cancer Research

Frequent coauthors who have collaborated with Segall multiple times include Mingming Wu, Louis Hodgson, Brian C. H. Cheung, Mrinal Pandey, and Young Joon Suh.

Publication venues appearing most often in Segall's work consist of:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Cancer Research
  • Physical Biology
  • Communications Biology

Best Publications

  • A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors.

    Jeffrey Wyckoff;Weigang Wang;Elaine Y. Lin;Yarong Wang

  • Direct Visualization of Macrophage-Assisted Tumor Cell Intravasation in Mammary Tumors

    Jeffrey B. Wyckoff;Yarong Wang;Elaine Y. Lin;Jiu Feng Li

  • Intravital imaging of cell movement in tumours

    John Condeelis;Jeffrey E. Segall

  • Classifying collective cancer cell invasion

    Peter Friedl;Joseph Locker;Erik Sahai;Jeffrey E. Segall

  • Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop

    Sumanta Goswami;Erik Sahai;Erik Sahai;Jeffrey B. Wyckoff;Michael Cammer

  • Molecular mechanisms of invadopodium formation the role of the N-WASP–Arp2/3 complex pathway and cofilin

    Hideki Yamaguchi;Mike Lorenz;Stephan Kempiak;Corina Sarmiento

  • Temporal comparisons in bacterial chemotaxis.

    Jeffrey E. Segall;Steven M. Block;Howard C. Berg

  • Identification and Testing of a Gene Expression Signature of Invasive Carcinoma Cells within Primary Mammary Tumors

    Weigang Wang;Sumanta Goswami;Kyle Lapidus;Amber L. Wells

  • A Critical Step in Metastasis: In Vivo Analysis of Intravasation at the Primary Tumor

    Jeffrey B. Wyckoff;Joan G. Jones;John S. Condeelis;Jeffrey E. Segall

  • Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling.

    Weigang Wang;Jeffrey B. Wyckoff;Victoria Centonze Frohlich;Yuri Oleynikov

  • The great escape: when cancer cells hijack the genes for chemotaxis and motility.

    John Condeelis;Robert H. Singer;Jeffrey E. Segall

  • Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling.

    Salvatore J Coniglio;Eliseo Eugenin;Kostantin Dobrenis;E Richard Stanley

  • The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation.

    Richard G. Pestell;Chris Albanese;Anne T. Reutens;Jeffrey E. Segall

  • Intravital imaging of metastatic behavior through a Mammary Imaging Window

    Dmitriy Kedrin;Bojana Gligorijevic;Jeffrey Wyckoff;Vladislav V Verkhusha

  • Impulse responses in bacterial chemotaxis.

    Steven M. Block;Jeffrey E. Segall;Howard C. Berg

  • Adaptation kinetics in bacterial chemotaxis.

    Steven M. Block;Jeffrey E. Segall;Howard Curtis Berg

  • Integration of Rac-dependent Regulation of Cyclin D1 Transcription through a Nuclear Factor-κB-dependent Pathway

    David Joyce;Boumediene Bouzahzah;Maofu Fu;Chris Albanese

  • Tumor cells caught in the act of invading: their strategy for enhanced cell motility.

    Weigang Wang;Sumanta Goswami;Erik Sahai;Jeffrey B. Wyckoff

  • Polarization of yeast cells in spatial gradients of alpha mating factor

    Jeffrey E. Segall

  • Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy.

    Erik Sahai;Erik Sahai;Jeffrey Wyckoff;Ulrike Philippar;Jeffrey E Segall

Frequent Co-Authors

John S. Condeelis
John S. Condeelis Albert Einstein College of Medicine
Michael B. Prystowsky
Michael B. Prystowsky Albert Einstein College of Medicine
Erik Sahai
Erik Sahai The Francis Crick Institute
Jeffrey W. Pollard
Jeffrey W. Pollard University of Edinburgh
Marc Symons
Marc Symons Feinstein Institute for Medical Research
Jonathan M. Backer
Jonathan M. Backer Albert Einstein College of Medicine
Jacco van Rheenen
Jacco van Rheenen Antoni van Leeuwenhoek Hospital
Howard C. Berg
Howard C. Berg Harvard University
E. Richard Stanley
E. Richard Stanley Albert Einstein College of Medicine
Joseph Locker
Joseph Locker University of Pittsburgh

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