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Medicine

D-Index
130
Citations
65925
World Ranking
2489
National Ranking
1404

Overview

Robert M. Hoffman is affiliated with AntiCancer in the United States and has a substantial record of research contributions mainly in the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work spans key subfields such as Biotechnology, Oncology, Molecular Biology, Biomedical Engineering, and Genetics.

The scientist's research topics include a concentrated focus on Cancer Research and Treatments, Nanoplatforms for cancer theranostics, Virus-based gene therapy research, Cancer, Hypoxia, and Metabolism, Cancer-related Molecular Pathways, Cancer Cells and Metastasis, and Epigenetics and DNA Methylation.

Robert M. Hoffman has published extensively, with frequent appearances in venues such as Anticancer Research, In Vivo, Cancer Genomics & Proteomics, Cancer Diagnosis & Prognosis, and PLoS ONE.

Some notable papers include:

  • Oncogenic miRNAs Identified in Tear Exosomes From Metastatic Breast Cancer Patients, 2020, Anticancer Research
  • Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells, 2020, Biochemical and Biophysical Research Communications
  • Oral dosing of Recombinant Methioninase Is Associated With a 70% Drop in PSA in a Patient With Bone-metastatic Prostate Cancer and 50% Reduction in Circulating Methionine in a High-stage Ovarian Cancer Patient, 2020, Anticancer Research
  • The Mucin Family of Proteins: Candidates as Potential Biomarkers for Colon Cancer, 2023, Cancers
  • RETRACTED: Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma, 2020, Therapeutic Advances in Medical Oncology

Frequent collaborators include Michael Bouvet, Qinghong Han, Jun Yamamoto, YUSUKE AOKI, and Yutaro Kubota.

Best Publications

  • Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

    Katarina Wolf;Mariska te Lindert;Marina Krause;Stephanie Alexander

  • A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy.

    Clemens A. Schmitt;Jordan S. Fridman;Meng Yang;Soyoung Lee

  • Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

    Mitomu Kioi;Hannes Vogel;Geoffrey Schultz;Robert M. Hoffman

  • The multiple uses of fluorescent proteins to visualize cancer in vivo

    Robert M. Hoffman

  • Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling

    Wei Tan;Weizhou Zhang;Amy Strasner;Sergei Grivennikov

  • Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases

    Meng Yang;Eugene Baranov;Ping Jiang;Fang-Xian Sun

  • Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic.

    Robert M. Hoffman

  • Dissecting p53 tumor suppressor functions in vivo

    Clemens A Schmitt;Jordan S Fridman;Meng Yang;Eugene Baranov

  • Biomimetic amplification of nanoparticle homing to tumors

    Dmitri Simberg;Tasmia Duza;Ji Ho Park;Markus Essler

  • Gene expression profiling predicts clinical outcome of prostate cancer.

    Gennadi V. Glinsky;Anna B. Glinskii;Andrew James Stephenson;Robert M. Hoffman

  • Transdifferentiation of glioblastoma cells into vascular endothelial cells

    Yasushi Soda;Tomotoshi Marumoto;Tomotoshi Marumoto;Dinorah Friedmann-Morvinski;Mie Soda

  • Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium

    Ming Zhao;Meng Yang;Xiao-Ming Li;Ping Jiang

  • Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons.

    Yasuyuki Amoh;Lingna Li;Kensei Katsuoka;Sheldon Penman

  • Patient-derived orthotopic xenografts: better mimic of metastasis than subcutaneous xenografts.

    Robert M. Hoffman

  • Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling

    Guobin He;Debanjan Dhar;Hayato Nakagawa;Hayato Nakagawa;Joan Font-Burgada

  • Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.

    Robert M. Hoffman

  • Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves

    Yasuyuki Amoh;Lingna Li;Raul Campillo;Katsumasa Kawahara

  • A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically with histologically intact patient specimens

    Xinyu Fu;Fiorella Guadagni;Robert M. Hoffman

  • Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens.

    Xinyu Fu;Jeffrey M. Besterman;Ann Monosov;Robert M. Hoffman

  • Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

    Chris Folkins;Yuval Shaked;Shan Man;Terence Tang

Frequent Co-Authors

Michael Bouvet
Michael Bouvet University of California, San Diego
Ming Zhao
Ming Zhao Pfizer (United States)
Itaru Endo
Itaru Endo Yokohama City University
Toshiyoshi Fujiwara
Toshiyoshi Fujiwara Okayama University
Hisataka Moriwaki
Hisataka Moriwaki Gifu University
Katsuro Tomita
Katsuro Tomita Kanazawa University
Michiaki Unno
Michiaki Unno Tohoku University
Takahiro Kunisada
Takahiro Kunisada Gifu University
Jason B. Fleming
Jason B. Fleming The University of Texas MD Anderson Cancer Center
Mark A. Talamini
Mark A. Talamini Stony Brook University

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