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D-Index
102
Citations
38434
World Ranking
7663
National Ranking
3988

Overview

Hisataka Kobayashi is affiliated with the National Institutes of Health in the United States. Their research spans multiple interdisciplinary fields, focusing primarily on medicine, engineering, and immunology and microbiology. Within these main fields, Kobayashi's work concentrates on subfields such as pulmonary and respiratory medicine, biomedical engineering, immunology, oncology, and biotechnology.

Kobayashi's research topics cover a range of areas related to cancer treatment and immune response mechanisms. Specifically, their work includes nanoplatforms for cancer theranostics, photodynamic therapy research studies, immunotherapy and immune responses, cancer research and treatments, cancer immunotherapy and biomarkers, cancer hypoxia and metabolism, and peptidase inhibition and analysis.

Several publications authored or coauthored by Kobayashi illustrate their contributions to these fields. Selected recent papers include:

  • Near-infrared photoimmunotherapy of cancer: a new approach that kills cancer cells and enhances anti-cancer host immunity (2020), International Immunology
  • Norcyanine-Carbamates Are Versatile Near-Infrared Fluorogenic Probes (2021), Journal of the American Chemical Society
  • Combined CD44- and CD25-Targeted Near-Infrared Photoimmunotherapy Selectively Kills Cancer and Regulatory T Cells in Syngeneic Mouse Cancer Models (2020), Cancer Immunology Research
  • Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer (2021), Scientific Reports
  • Near Infrared Photoimmunotherapy; A Review of Targets for Cancer Therapy (2021), Cancers

The venues in which Kobayashi frequently publishes include:

  • Cancers
  • Cancer Science
  • Cancer Research
  • Cancer Immunology Immunotherapy
  • EBioMedicine

Kobayashi collaborates regularly with several frequent coauthors, among them:

  • Peter L. Choyke
  • Aki Furusawa
  • Takuya Kato
  • Ryuhei Okada
  • Hiroaki Wakiyama

This collaboration network and choice of publication venues underline Kobayashi's involvement in cancer immunology and engineering approaches to therapeutic development.

Best Publications

  • New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging

    Hisataka Kobayashi;Mikako Ogawa;Raphael Alford;Peter L. Choyke

  • Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats.

    Michelle Longmire;Peter L Choyke;Hisataka Kobayashi

  • Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

    Yuko Nakamura;Ai Mochida;Peter L. Choyke;Hisataka Kobayashi

  • Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

    Makoto Mitsunaga;Mikako Ogawa;Nobuyuki Kosaka;Lauren T Rosenblum

  • Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes.

    Yasuteru Urano;Daisuke Asanuma;Yukihiro Hama;Yukihiro Hama;Yoshinori Koyama;Yoshinori Koyama

  • Toxicity of organic fluorophores used in molecular imaging: literature review.

    Raphael Alford;Haley M. Simpson;Josh Duberman;G. Craig Hill

  • Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications.

    Hisataka Kobayashi;Peter L. Choyke

  • Rapid Cancer Detection by Topically Spraying a γ-Glutamyltranspeptidase–Activated Fluorescent Probe

    Yasuteru Urano;Masayo Sakabe;Nobuyuki Kosaka;Mikako Ogawa

  • In vivo Molecular Imaging of Cancer with a Quenching Near Infrared Fluorescent Probe Using Conjugates of Monoclonal Antibodies and Indocyanine Green

    Mikako Ogawa;Nobuyuki Kosaka;Peter L. Choyke;Hisataka Kobayashi

  • Near-Infrared Photoimmunotherapy of Cancer

    Hisataka Kobayashi;Peter L. Choyke

  • Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance.

    Hisataka Kobayashi;Sigrid Dubois;Noriko Sato;Helen Sabzevari

  • Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds.

    Hiroyuki Ueda;Kaori Togashi;Ikuo Konishi;Milliam L. Kataoka

  • Dendrimer-based nanoprobe for dual modality magnetic resonance and fluorescence imaging.

    Vladimir S Talanov;Celeste A S Regino;Hisataka Kobayashi;Marcelino Bernardo

  • Fluorescence-Guided Surgery.

    Tadanobu Nagaya;Yu A. Nakamura;Peter L. Choyke;Hisataka Kobayashi

  • Sensitive β-galactosidase-targeting fluorescence probe for visualizing small peritoneal metastatic tumours in vivo

    Daisuke Asanuma;Masayo Sakabe;Mako Kamiya;Kyoko Yamamoto

  • Macromolecular MRI Contrast Agents with Small Dendrimers: Pharmacokinetic Differences between Sizes and Cores

    Hisataka Kobayashi;Satomi Kawamoto;Sang Kyung Jo;Henry L. Bryant

  • Markedly Enhanced Permeability and Retention Effects Induced by Photo-immunotherapy of Tumors

    Kohei Sano;Takahito Nakajima;Peter L. Choyke;Hisataka Kobayashi

  • Hemodynamics in Vasculogenic Mimicry and Angiogenesis of Inflammatory Breast Cancer Xenograft

    Kazuo Shirakawa;Hisataka Kobayashi;Yuji Heike;Satomi Kawamoto

  • Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals

    Hisataka Kobayashi;Michelle R. Longmire;Mikako Ogawa;Peter L. Choyke

  • Dendrimer-based macromolecular MRI contrast agents: characteristics and application.

    Hisataka Kobayashi;Martin W. Brechbiel

Frequent Co-Authors

Peter L. Choyke
Peter L. Choyke National Institutes of Health
Martin W. Brechbiel
Martin W. Brechbiel National Institutes of Health
Yasuteru Urano
Yasuteru Urano University of Tokyo
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Jorge A. Carrasquillo
Jorge A. Carrasquillo Memorial Sloan Kettering Cancer Center
Baris Turkbey
Baris Turkbey National Institutes of Health
Robert A. Star
Robert A. Star National Institutes of Health
Junji Konishi
Junji Konishi Kyoto University
Tetsuo Nagano
Tetsuo Nagano University of Tokyo
Ira Pastan
Ira Pastan Center for Cancer Research

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