World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
101
Citations
28138
World Ranking
1243
National Ranking
480

Medicine

D-Index
105
Citations
31666
World Ranking
6861
National Ranking
3619

Overview

Martin W. Brechbiel is affiliated with the National Institutes of Health in the United States. Their research primarily spans the field of Medicine, with a substantial concentration in Radiology, Nuclear Medicine and Imaging, Oncology, Pulmonary and Respiratory Medicine, Radiation, and Organic Chemistry. This multidisciplinary focus reflects a broad engagement with both clinical and chemical sciences.

The scientist's work covers core topics such as Radiopharmaceutical Chemistry and Applications, Monoclonal and Polyclonal Antibodies Research, Medical Imaging Techniques and Applications, HER2/EGFR in Cancer Research, Synthesis and Biological Evaluation, Cancer Immunotherapy and Biomarkers, and Radiation Therapy and Dosimetry.

Martin W. Brechbiel has contributed extensively to scientific literature, with frequent publications in the following venues:

  • Cancer Biotherapy and Radiopharmaceuticals
  • Journal of Nuclear Medicine
  • Molecules
  • European Journal of Nuclear Medicine and Molecular Imaging
  • Medical Physics

Recent publications from this scientist include:

  • 90Y-Daclizumab (Anti-CD25), High-Dose Carmustine, Etoposide, Cytarabine, and Melphalan Chemotherapy and Autologous Hematopoietic Stem Cell Transplant Yielded Sustained Complete Remissions in 4 Patients with Recurrent Hodgkin's Lymphoma, 2020, Cancer Biotherapy and Radiopharmaceuticals
  • General Method to Increase Carboxylic Acid Content on Nanodiamonds, 2022, Molecules
  • Cure of Micrometastatic B-Cell Lymphoma in a SCID Mouse Model Using 213Bi-Anti-CD20 Monoclonal Antibody, 2022, Journal of Nuclear Medicine
  • Targeted α-Therapy, 2020, Cancer Biotherapy and Radiopharmaceuticals
  • National Cancer Institute support for targeted alpha-emitter therapy, 2021, European Journal of Nuclear Medicine and Molecular Imaging

Collaboration is a notable aspect of their research activity, frequently working with coauthors including Freddy E. Escorcia, Jacek Capala, Luca Filippi, Julie A. Hong, and Jeff Buchsbaum. These partnerships indicate a networked approach to advancing radiopharmaceutical and nuclear medicine research.

Best Publications

  • Macromolecules, Dendrimers, and Nanomaterials in Magnetic Resonance Imaging: The Interplay between Size, Function, and Pharmacokinetics

    Aaron Joseph L. Villaraza;Ambika Bumb;Martin W. Brechbiel

  • Nano-sized MRI contrast agents with dendrimer cores.

    Hisataka Kobayashi;Martin W Brechbiel

  • Targeted α particle immunotherapy for myeloid leukemia

    Joseph G. Jurcic;Steven M. Larson;Steven M. Larson;George Sgouros;George Sgouros;Michael R. McDevitt;Michael R. McDevitt

  • Antibody-targeted radiation cancer therapy

    Diane E. Milenic;Erik D. Brady;Martin W. Brechbiel

  • Synthesis of 1-(p-isothiocyanatobenzyl) derivatives of DTPA and EDTA. Antibody labeling and tumor-imaging studies

    Martin W. Brechbiel;Otto A. Gansow;Robert W. Atcher;Jeffrey Schlom

  • Growing Applications of “Click Chemistry” for Bioconjugation in Contemporary Biomedical Research

    Kido Nwe;Martin W. Brechbiel

  • Dendrimer-based nanoprobe for dual modality magnetic resonance and fluorescence imaging.

    Vladimir S Talanov;Celeste A S Regino;Hisataka Kobayashi;Marcelino Bernardo

  • Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac.

    T A Waldmann;J D White;J A Carrasquillo;J C Reynolds

  • MRI of tumor angiogenesis.

    Tristan Barrett;Martin Brechbiel;Marcelino Bernardo;Peter L. Choyke

  • Macromolecular MRI Contrast Agents with Small Dendrimers: Pharmacokinetic Differences between Sizes and Cores

    Hisataka Kobayashi;Satomi Kawamoto;Sang Kyung Jo;Henry L. Bryant

  • Synthesis and relaxometry of high-generation (G = 5, 7, 9, and 10) PAMAM dendrimer-DOTA-gadolinium chelates.

    L. Henry Bryant;Martin W. Brechbiel;Chuanchu Wu;Jeff W. M. Bulte

  • Targeting Dendrimer-Chelates to Tumors and Tumor Cells Expressing the High-Affinity Folate Receptor

    Erik C. Wiener;Sheela Konda;Amber Shadron;Martin Brechbiel

  • An α-Particle Emitting Antibody ([213Bi]J591) for Radioimmunotherapy of Prostate Cancer

    Michael R. McDevitt;Els Barendswaard;Dangshe Ma;Lawrence Lai

  • An overview of targeted alpha therapy

    Young-Seung Kim;Martin W. Brechbiel

  • A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

    Andrew M Scott;Fook-Thean Lee;Niall Tebbutt;Rebecca Herbertson

  • Development of radioimmunotherapeutic and diagnostic antibodies : an inside-out view

    C. Andrew Boswell;Martin W. Brechbiel

  • Specific targeting of folate–dendrimer MRI contrast agents to the high affinity folate receptor expressed in ovarian tumor xenografts

    Sheela D. Konda;Michael Aref;Steven Wang;Martin Brechbiel

  • Hemodynamics in Vasculogenic Mimicry and Angiogenesis of Inflammatory Breast Cancer Xenograft

    Kazuo Shirakawa;Hisataka Kobayashi;Yuji Heike;Satomi Kawamoto

  • Nature of the bifunctional chelating agent used for radioimmunotherapy with yttrium-90 monoclonal antibodies: critical factors in determining in vivo survival and organ toxicity.

    Robert W. Kozak;Andrew Raubitschek;Saed Mirzadeh;Martin W. Brechbiel

  • Alpha-Emitting Bismuth Cyclohexylbenzyl DTPA Constructs of Recombinant Humanized Anti-CD33 Antibodies: Pharmacokinetics, Bioactivity, Toxicity and Chemistry

    T. K. Nikula;M. R. Mcdevitt;R. D. Finn;Chuanchu Wu

  • Dendrimer-based macromolecular MRI contrast agents: characteristics and application.

    Hisataka Kobayashi;Martin W. Brechbiel

Frequent Co-Authors

Diane E. Milenic
Diane E. Milenic National Institutes of Health
Hisataka Kobayashi
Hisataka Kobayashi National Institutes of Health
Peter L. Choyke
Peter L. Choyke National Institutes of Health
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Robert A. Star
Robert A. Star National Institutes of Health
Suzy V. Torti
Suzy V. Torti University of Connecticut Health Center
Kaori Togashi
Kaori Togashi Kyoto University
Robin D. Rogers
Robin D. Rogers University of Alabama
Jorge A. Carrasquillo
Jorge A. Carrasquillo Memorial Sloan Kettering Cancer Center
Junji Konishi
Junji Konishi Kyoto University

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