Anna Orlova focuses on Affibody molecule, Biodistribution, Cancer research, Molecular imaging and Pathology. Her research in Affibody molecule intersects with topics in Molecular biology, Biophysics and Cysteine. Anna Orlova combines subjects such as Immunology, Oligopeptide, Peptide, Peptide synthesis and Histidine with her study of Biodistribution.
Her Cancer research research is multidisciplinary, incorporating elements of Preclinical imaging, Trastuzumab, Tyrosine kinase, Tumour targeting and Antibody. Her Molecular imaging research focuses on Epidermal growth factor receptor and how it relates to Dimer and A431 cells. Her Pathology research is multidisciplinary, relying on both Pet imaging, Positron emission tomography, Receptor and Breast cancer.
Her primary areas of investigation include Biodistribution, Cancer research, Affibody molecule, Molecular imaging and In vitro. Her work in Biodistribution tackles topics such as Biophysics which are related to areas like Molecule and Stereochemistry. Her work carried out in the field of Cancer research brings together such families of science as Cancer, Prostate cancer, Pathology, Receptor and Monoclonal antibody.
Anna Orlova has researched Affibody molecule in several fields, including Preclinical imaging, Epidermal growth factor receptor, Nuclear medicine, DOTA and Combinatorial chemistry. The various areas that Anna Orlova examines in her Molecular imaging study include Scaffold protein, Molecular targets, Positron emission tomography, Breast cancer and DARPin. Her research integrates issues of Molecular biology and Radionuclide therapy in her study of In vitro.
Her scientific interests lie mostly in Biodistribution, Molecular imaging, Cancer research, In vitro and Biophysics. Her study in Biodistribution focuses on Affibody molecule in particular. Her studies in Affibody molecule integrate themes in fields like Cancer cell and Cytotoxic T cell.
As a member of one scientific family, she mostly works in the field of Molecular imaging, focusing on Scaffold protein and, on occasion, Spect imaging and Cancer. Her Cancer research research is multidisciplinary, incorporating perspectives in Molecular medicine, Targeted therapy, DARPin, Prostate cancer and Monoclonal antibody. Her studies deal with areas such as Chelation, Her2 expression, Denaturation and Circular dichroism as well as Biophysics.
Her main research concerns Biodistribution, Molecular imaging, Biophysics, Scaffold protein and Cancer research. Her Biodistribution research is under the purview of In vitro. Her work deals with themes such as Molecule, Breast cancer, DARPin and Binding selectivity, which intersect with Molecular imaging.
Anna Orlova has included themes like Chelation, Cancer and Affibody molecule in her Biophysics study. Her biological study spans a wide range of topics, including Trimer, DOTA, Endogeny, Glutaric acid and Receptor expression. Anna Orlova works mostly in the field of Cancer research, limiting it down to concerns involving Prostate cancer and, occasionally, Receptor, Radionuclide therapy, Antagonist, Peptide and Trastuzumab.
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Tumor imaging using a picomolar affinity HER2 binding affibody molecule.
Anna Orlova;Mikaela Magnusson;Tove L.J. Eriksson;Martin Nilsson.
Cancer Research (2006)
Molecular Imaging of HER2-Expressing Malignant Tumors in Breast Cancer Patients Using Synthetic 111In- or 68Ga-Labeled Affibody Molecules
Richard P. Baum;Vikas Prasad;Dirk Müller;Christiane Schuchardt.
The Journal of Nuclear Medicine (2010)
Radionuclide Therapy of HER2-Positive Microxenografts Using a 177Lu-Labeled HER2-Specific Affibody Molecule
Vladimir Tolmachev;Anna Orlova;Rikard Pehrson;Joakim Galli.
Cancer Research (2007)
Synthetic Affibody Molecules: A Novel Class of Affinity Ligands for Molecular Imaging of HER2-Expressing Malignant Tumors
Anna Orlova;Vladimir Tolmachev;Rikard Pehrson;Malin Lindborg.
Cancer Research (2007)
Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding Affibody molecule
Mikaela Friedman;Anna Orlova;Eva Johansson;Tove L. J. Eriksson.
Journal of Molecular Biology (2008)
Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy.
Vladimir Tolmachev;Anna Orlova;Fredrik Y Nilsson;Joachim Feldwisch.
Expert Opinion on Biological Therapy (2007)
On the Selection of a Tracer for PET Imaging of HER2-Expressing Tumors: Direct Comparison of a 124I-Labeled Affibody Molecule and Trastuzumab in a Murine Xenograft Model
Anna Orlova;Helena Wållberg;Sharon Stone-Elander;Vladimir Tolmachev.
The Journal of Nuclear Medicine (2009)
Measuring HER2-Receptor Expression In Metastatic Breast Cancer Using [68Ga]ABY-025 Affibody PET/CT
Jens Sörensen;Irina Velikyan;Dan Sandberg;Anders Wennborg.
Theranostics (2016)
Affibody Molecules for Epidermal Growth Factor Receptor Targeting In Vivo: Aspects of Dimerization and Labeling Chemistry
Vladimir Tolmachev;Mikaela Friedman;Mattias Sandström;Tove L.J. Eriksson.
The Journal of Nuclear Medicine (2009)
Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m
Javad Garousi;Sarah Lindbo;Bogdan Mitran;Jos Buijs.
Scientific Reports (2017)
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