Anna Orlova

Overview

Best Publications

• Tumor imaging using a picomolar affinity HER2 binding affibody molecule.

  Anna Orlova;Mikaela Magnusson;Tove L.J. Eriksson;Martin Nilsson

  649
  Citations

• Molecular Imaging of HER2-Expressing Malignant Tumors in Breast Cancer Patients Using Synthetic 111In- or 68Ga-Labeled Affibody Molecules

  Richard P. Baum;Vikas Prasad;Dirk Müller;Christiane Schuchardt

  354
  Citations

• Radionuclide Therapy of HER2-Positive Microxenografts Using a 177Lu-Labeled HER2-Specific Affibody Molecule

  Vladimir Tolmachev;Anna Orlova;Rikard Pehrson;Joakim Galli

  265
  Citations

• Measuring HER2-Receptor Expression In Metastatic Breast Cancer Using [68Ga]ABY-025 Affibody PET/CT.

  Jens Sörensen;Irina Velikyan;Dan Sandberg;Anders Wennborg

  241
  Citations

• Synthetic Affibody Molecules: A Novel Class of Affinity Ligands for Molecular Imaging of HER2-Expressing Malignant Tumors

  Anna Orlova;Vladimir Tolmachev;Rikard Pehrson;Malin Lindborg

  238
  Citations

• Directed evolution to low nanomolar affinity of a tumor-targeting epidermal growth factor receptor-binding Affibody molecule

  Mikaela Friedman;Anna Orlova;Eva Johansson;Tove L. J. Eriksson

  195
  Citations

• Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy.

  Vladimir Tolmachev;Anna Orlova;Fredrik Y Nilsson;Joachim Feldwisch

  164
  Citations

• On the Selection of a Tracer for PET Imaging of HER2-Expressing Tumors: Direct Comparison of a 124I-Labeled Affibody Molecule and Trastuzumab in a Murine Xenograft Model

  Anna Orlova;Helena Wållberg;Sharon Stone-Elander;Vladimir Tolmachev

  161
  Citations

• Pharmacologic inhibition of STAT5 in acute myeloid leukemia

  Bettina Wingelhofer;Barbara Maurer;Elizabeth C Heyes;Abbarna A Cumaraswamy

  147
  Citations

• Affibody Molecules for Epidermal Growth Factor Receptor Targeting In Vivo: Aspects of Dimerization and Labeling Chemistry

  Vladimir Tolmachev;Mikaela Friedman;Mattias Sandström;Tove L.J. Eriksson

  144
  Citations

• Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-ZEGFR:2377 Affibody molecule: aspect of the injected tracer amount

  Vladimir Tolmachev;Daniel Rosik;Helena Wållberg;Anna Sjöberg

  141
  Citations

• 111In-Benzyl-DTPA–ZHER2:342, an Affibody-Based Conjugate for In Vivo Imaging of HER2 Expression in Malignant Tumors

  Vladimir Tolmachev;Fredrik Y Nilsson;Charles Widström;Karl Andersson

  139
  Citations

• 99mTc-maEEE-ZHER2:342, an Affibody Molecule-Based Tracer for the Detection of HER2 Expression in Malignant Tumors

  Thuy Tran;Torun Engfeldt;Anna Orlova;Mattias Sandström

  139
  Citations

• Targeting of HER2-Expressing Tumors with a Site-Specifically 99mTc-Labeled Recombinant Affibody Molecule, ZHER2:2395, with C-Terminally Engineered Cysteine

  Sara Ahlgren;Helena Wållberg;Thuy A. Tran;Charles Widström

  138
  Citations

• Slow Internalization of Anti-HER2 Synthetic Affibody Monomer 111In-DOTA-ZHER2:342-pep2 : Implications for Development of Labeled Tracers

  Helena Wållberg;Anna Orlova

  137
  Citations

• Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single-photon imaging of HER2 expression in tumors

  Anna Orlova;Fredrik Y. Nilsson;Maria Wikman;Charles Widström

  134
  Citations

• Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules.

  Sara Ahlgren;Anna Orlova;Daniel Rosik;Mattias Sandström

  131
  Citations

• Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence.

  Torun Engfeldt;Anna Orlova;Thuy Tran;Alexander Bruskin

  126
  Citations

• Targeting of HER2-Expressing Tumors Using 111In-ABY-025, a Second-Generation Affibody Molecule with a Fundamentally Reengineered Scaffold

  Sara Ahlgren;Anna Orlova;Helena Wållberg;Monika Hansson

  116
  Citations

• Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology.

  Ahmet Krasniqi;Matthias D’Huyvetter;Nick Devoogdt;Fredrik Y. Frejd

  112
  Citations