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Lena Claesson-Welsh

Lena Claesson-Welsh

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Best Female Scientists
2025
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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Best Female Scientists

D-Index
109
Citations
51061
World Ranking
923
National Ranking
10

Biology and Biochemistry

D-Index
110
Citations
52522
World Ranking
964
National Ranking
17

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2016 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Lena Claesson-Welsh is affiliated with Uppsala University in Sweden. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on several related subfields including Molecular Biology, Cell Biology, Oncology, Neurology, and Immunology.

The primary research topics addressed by Lena Claesson-Welsh include:

  • Angiogenesis and VEGF in Cancer
  • Barrier Structure and Function Studies
  • Cell Adhesion Molecules Research
  • Lymphatic System and Diseases
  • Axon Guidance and Neuronal Signaling
  • Hippo pathway signaling and YAP/TAZ
  • Wnt/β-catenin signaling in development and cancer

Their recent published papers are:

  • "Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies," 2020, Trends in Molecular Medicine
  • "Endothelial Unc5B controls blood-brain barrier integrity," 2022, Nature Communications
  • "Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin," 2020, eLife
  • "Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways," 2021, Frontiers in Physiology
  • "Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension," 2022, Circulation

Lena Claesson-Welsh collaborates frequently with several co-authors, including:

  • Mark Richards
  • Emmanuel Nwadozi
  • Ross Smith
  • Sagnik Pal
  • Takeshi Ninchoji

Their work has been published repeatedly in several scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Nature Cardiovascular Research
  • Journal of Clinical Investigation
  • Frontiers in Physiology

Lena Claesson-Welsh has been recognized as a member of notable scientific organizations, including:

  • Member of Academia Europaea (2016)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • VEGF receptor signalling - in control of vascular function.

    Anna-Karin Olsson;Anna Dimberg;Johan Kreuger;Lena Claesson-Welsh

  • Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

    J Waltenberger;L Claesson-Welsh;A Siegbahn;M Shibuya

  • Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

    Masabumi Shibuya;Lena Claesson-Welsh

  • Mechanisms and regulation of endothelial VEGF receptor signalling

    Michael Simons;Emma Gordon;Lena Claesson-Welsh

  • FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition.

    Michael J Cross;Lena Claesson-Welsh

  • 2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165) INHIBITION OF RECEPTOR BINDING AND VEGF-INDUCED VASCULAR PERMEABILITY THROUGH INTERACTIONS REQUIRING THE EXON 7-ENCODED DOMAIN

    Judy Ruckman;Louis S. Green;Jim Beeson;Sheela Waugh

  • Regulation of angiogenesis via vascular endothelial growth factor receptors.

    Tanja Veikkola;Marika Karkkainen;Lena Claesson-Welsh;Kari Alitalo

  • Proteolytic processing regulates receptor specificity and activity of VEGF-C

    Vladimir Joukov;Tarja Sorsa;Vijay Kumar;Michael Jeltsch

  • Signal transduction by vascular endothelial growth factor receptors.

    Sina Koch;Sònia Tugues;Xiujuan Li;Laura Gualandi

  • Signal Transduction by Vascular Endothelial Growth Factor Receptors

    Sina Koch;Lena Claesson-Welsh

  • Platelet-derived Growth Factor and Its Receptors in Human Glioma Tissue: Expression of Messenger RNA and Protein Suggests the Presence of Autocrine and Paracrine Loops

    Monica Hermanson;Keiko Funa;Magdalena Hartman;Lena Claesson-Welsh

  • VEGF-receptor signal transduction

    Michael J. Cross;Johan Dixelius;Taro Matsumoto;Lena Claesson-Welsh

  • VEGFA and tumour angiogenesis.

    Lena Claesson-Welsh;Michael J. Welsh

  • A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2.

    Jian Hua Qi;Quteba Ebrahem;Nina Moore;Gillian Murphy

  • HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

    Charlotte Rolny;Massimiliano Mazzone;Sònia Tugues;Damya Laoui

  • Vascular endothelial growth factor C induces angiogenesis in vivo

    Yihai Cao;Philip Linden;Jacob Farnebo;Renhai Cao

  • Platelet-derived growth factor receptor signals.

    L Claesson-Welsh

  • VEGF receptor signal transduction.

    Taro Matsumoto;Lena Claesson-Welsh

  • PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

    Phillip T. Hawkins;Alicia Eguinoa;Rong-Guo Qiu;David Stokoe

  • FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

    J Partanen;T P Mäkelä;E Eerola;J Korhonen

Frequent Co-Authors

Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Bengt Westermark
Bengt Westermark Uppsala University
Michael Welsh
Michael Welsh Uppsala University
Christer Wernstedt
Christer Wernstedt Ludwig Cancer Research
Lars Rönnstrand
Lars Rönnstrand Lund University
Kohei Miyazono
Kohei Miyazono University of Tokyo
Kari Alitalo
Kari Alitalo University of Helsinki
Ulf Hellman
Ulf Hellman Ludwig Cancer Research
Elisabetta Dejana
Elisabetta Dejana Uppsala University

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