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D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
23022
World Ranking
3716
National Ranking
1844

Overview

Andrius Kazlauskas is affiliated with the University of Illinois at Chicago in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with a notable concentration in ophthalmology and molecular biology subfields.

The scientist has published extensively on several key topics related to eye health and molecular mechanisms, including:

  • Retinal Diseases and Treatments
  • Retinal Development and Disorders
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Retinal and Macular Surgery
  • Ocular Oncology and Treatments

Their recent contributions include the following research papers:

  • "The Renin-Angiotensin-Aldosterone System (RAAS) Is One of the Effectors by Which Vascular Endothelial Growth Factor (VEGF)/Anti-VEGF Controls the Endothelial Cell Barrier" (2020, American Journal Of Pathology)
  • "PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis" (2020, Diabetes)
  • "VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration" (2021, Investigative Ophthalmology & Visual Science)
  • "Resilience to diabetic retinopathy" (2024, Progress in Retinal and Eye Research)
  • "The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier" (2021, Investigative Ophthalmology & Visual Science)

Frequent publishing venues for Kazlauskas include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • International Journal of Molecular Sciences
  • American Journal Of Pathology
  • Investigative Ophthalmology & Visual Science
  • Progress in Retinal and Eye Research

Their collaborations reflect a network of frequent co-authors, which include:

  • Anara Serikbaeva
  • Basma Baccouche
  • Yueru Li
  • Hetian Lei
  • Jing Cui

This body of work aligns with the scientist's main fields of expertise and their focus on retinal conditions, angiogenesis, and molecular pathways influencing vascular and ocular biology. The research often bridges molecular biology and clinical implications for eye diseases.

Best Publications

  • PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

    Jongkyeong Chung;T. C. Grammer;K. P. Lemon;A. Kazlauskas

  • Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis.

    Silvia Svegliati Baroni;Mariarosaria Santillo;Federica Bevilacqua;Michele Luchetti

  • Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins.

    Andrius Kazlauskas;Jonathan A. Cooper

  • Regulation of chemotaxis by the platelet-derived growth factor receptor-β

    Vikas Kundra;Jaime A. Escobedo;Andrius Kazlauskas;Ha Kun Kim

  • c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

    Rina Plattner;Lisa Kadlec;Kris A. DeMali;Andrius Kazlauskas

  • Binding of GAP to activated PDGF receptors

    Andrius Kazlauskas;Christine Ellis;Tony Pawson;Jonathan A. Cooper

  • Platelet-derived Growth Factor-induced H2O2 Production Requires the Activation of Phosphatidylinositol 3-Kinase

    Yun Soo Bae;Jee Young Sung;Ohn Soon Kim;Yeun Ju Kim

  • Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.

    A Kashishian;A Kazlauskas;J A Cooper

  • EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

    Kazunori Akimoto;Ryo Takahashi;Shigeharu Moriya;Naoya Nishioka

  • Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase.

    A Kazlauskas;J A Cooper

  • Phosphoinositide 3-Kinase Regulates Phospholipase Cγ-mediated Calcium Signaling

    Lucia E. Rameh;Sue Goo Rhee;Katherine Spokes;Andrius Kazlauskas

  • Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes

    Stephan Rosenkranz;Andrius Kazlauskas

  • GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

    A Kazlauskas;A Kashishian;J A Cooper;M Valius

  • The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp

    A. Kazlauskas;Gen-Sheng Feng;T. Pawson;M. Valius

  • Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation

    J.D. Kelly;B.A. Haldeman;F.J. Grant;M.J. Murray

  • Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase.

    Degui Wang;H-J. Su Huang;Andrius Kazlauskas;Webster K. Cavenee

  • Axl is essential for VEGF-A-dependent activation of PI3K/Akt

    Guo-Xiang Ruan;Andrius Kazlauskas

  • Receptor tyrosine kinases and their targets.

    Andrius Kazlauskas

  • Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase.

    Shigeharu Moriya;Andrius Kazlauskas;Kazunori Akimoto;Syu Ichi Hirai

  • Phosphatidylinositol 3-Kinase Activity Is Required at a Postendocytic Step in Platelet-derived Growth Factor Receptor Trafficking

    Marguerite Joly;Andrius Kazlauskas;Silvia Corvera

Frequent Co-Authors

Reza Dana
Reza Dana Massachusetts Eye and Ear Infirmary
Stephan Rosenkranz
Stephan Rosenkranz University of Cologne
Alex Toker
Alex Toker Beth Israel Deaconess Medical Center
Shi Yuan Cheng
Shi Yuan Cheng Northwestern University
James D. Zieske
James D. Zieske Massachusetts Eye and Ear Infirmary
Amy Bernard
Amy Bernard Kavli Foundation
R. Adron Harris
R. Adron Harris The University of Texas at Austin
Thomas V. Dunwiddie
Thomas V. Dunwiddie University of Colorado Anschutz Medical Campus
Jeff L. Weiner
Jeff L. Weiner Wake Forest University
Patricia A. D'Amore
Patricia A. D'Amore Massachusetts Eye and Ear Infirmary

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