1999 - Hellman Fellow
Anthony J. Koleske focuses on Cell biology, Transcription factor II D, RNA polymerase II, General transcription factor and Tyrosine kinase. His studies in Cell biology integrate themes in fields like Cortactin and Cytoskeleton. His research integrates issues of Molecular biology, Transcription factor II F and RNA polymerase II holoenzyme in his study of Transcription factor II D.
The various areas that Anthony J. Koleske examines in his RNA polymerase II holoenzyme study include RNA polymerase I and Sigma factor. His work deals with themes such as Ubiquitin ligase and Phosphorylation, which intersect with Tyrosine kinase. His studies deal with areas such as Invadopodia and Invadopodium as well as Phosphorylation.
His primary areas of investigation include Cell biology, ABL, Tyrosine kinase, Dendritic spine and Neuroscience. His biological study spans a wide range of topics, including Cortactin, Actin cytoskeleton and Cytoskeleton. His ABL research includes elements of SH3 domain, Receptor tyrosine kinase, Kinase and Cell morphogenesis.
His Tyrosine kinase research includes themes of Cancer research and Kinase activity. His work on Hippocampal formation, Dendrite, Hippocampus and Excitatory postsynaptic potential as part of general Neuroscience study is frequently connected to Orbitofrontal cortex, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Phosphorylation study incorporates themes from Tyrosine and Signal transduction.
Anthony J. Koleske mainly investigates Cell biology, Dendritic spine, Actin, Cytoskeleton and Tyrosine kinase. The concepts of his Cell biology study are interwoven with issues in Phosphodiesterase, Transcription factor and Integrin binding. His Dendritic spine study improves the overall literature in Neuroscience.
His work carried out in the field of Actin brings together such families of science as Spectrin, Neurotransmitter receptor, Actin cytoskeleton, Ion channel and Cortactin. Anthony J. Koleske has researched Cytoskeleton in several fields, including Cell morphology, CDC42, Guanine nucleotide exchange factor and Ectopic expression. His research in the fields of ABL overlaps with other disciplines such as Catenin.
Anthony J. Koleske focuses on Cell biology, Actin, Dendritic spine, Cancer research and Neuroscience. When carried out as part of a general Cell biology research project, his work on Fibronectin is frequently linked to work in Dephosphorylation, therefore connecting diverse disciplines of study. The study incorporates disciplines such as GTPase, Biophysics, Protein filament, Site-directed mutagenesis and Protein–protein interaction in addition to Actin.
His research in Dendritic spine intersects with topics in Actin filament binding and Cortactin. His Neuroscience study integrates concerns from other disciplines, such as Schizophrenia and Knockout mouse. His Hippocampus research incorporates themes from Neurodevelopmental disorder and Long-term potentiation.
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An RNA polymerase II holoenzyme responsive to activators
Anthony J. Koleske;Richard A. Young.
Nature (1994)
Reduction of caveolin and caveolae in oncogenically transformed cells
Anthony J. Koleske;David Baltimore;Michael P. Lisanti.
Proceedings of the National Academy of Sciences of the United States of America (1995)
A Multisubunit Complex Associated with the RNA Polymerase II CTD and TATA-Binding Protein in Yeast
Craig M. Thompson;Anthony J. Koleske;David M. Chao;Richard A. Young.
Cell (1993)
Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein
Ji Won Um;Adam C. Kaufman;Mikhail Kostylev;Jacqueline K. Heiss.
Neuron (2013)
A kinase–cyclin pair in the RNA polymerase II holoenzyme
Sha-Mei Liao;Jianhua Zhang;D. A. Jeffery;A. J. Koleske.
Nature (1995)
Essential Roles for the Abl and Arg Tyrosine Kinases in Neurulation
Anthony J Koleske;Ann M Gifford;Martin L Scott;Michelle Nee.
Neuron (1998)
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
Matthew Oser;Hideki Yamaguchi;Hideki Yamaguchi;Christopher C. Mader;J.J. Bravo-Cordero.
Journal of Cell Biology (2009)
The RNA polymerase II holoenzyme and its implications for gene regulation.
Anthony J. Koleske;Richard A. Young.
Trends in Biochemical Sciences (1995)
Association of an activator with an RNA polymerase II holoenzyme.
Christoph J. Hengartner;Craig M. Thompson;Jianhua Zhang;David M. Chao.
Genes & Development (1995)
Molecular mechanisms of dendrite stability
Anthony J. Koleske.
Nature Reviews Neuroscience (2013)
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