Jeffrey Settleman

Overview

Best Publications

• Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

  Eunice L. Kwak;Yung-Jue Bang;D. Ross Camidge;Alice T. Shaw

  5280
  Citations

• Epidermal growth factor receptor mutations in lung cancer

  Sreenath V. Sharma;Daphne W. Bell;Daphne W. Bell;Jeffrey Settleman;Daniel A. Haber

  3688
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

  Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  2934
  Citations

• Systematic identification of genomic markers of drug sensitivity in cancer cells

  Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  2736
  Citations

• EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

  Anurag Singh;Jeffrey Settleman

  2588
  Citations

• Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

  Alice T. Shaw;Beow Y. Yeap;Mari Mino-Kenudson;Subba R. Digumarthy

  2340
  Citations

• Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

  Shyamala Maheswaran;Lecia V. Sequist;Sunitha Nagrath;Lindsey Ulkus

  2082
  Citations

• Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways

  Raffaella Sordella;Daphne W. Bell;Daniel A. Haber;Jeffrey Settleman

  2038
  Citations

• Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

  Eunice L. Kwak;Raffaella Sordella;Daphne W. Bell;Nadia Godin-Heymann

  1210
  Citations

• Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1.

  Xian-Feng Zhang;Jeffrey Settleman;John Kyriakis;Erika Takeuchi-Suzuki

  1094
  Citations

• EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib

  Ryan B. Corcoran;Hiromichi Ebi;Alexa B. Turke;Erin M. Coffee

  1070
  Citations

• First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring Somatic EGFR Mutations

  Lecia V. Sequist;Renato G. Martins;David Spigel;Steven M. Grunberg

  1029
  Citations

• Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

  Gromoslaw A. Smolen;Raffaella Sordella;Beth Muir;Gayatry Mohapatra

  731
  Citations

• SCF FBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

  Hiroyuki Inuzuka;Shavali Shaik;Ichiro Onoyama;Darning Gao

  683
  Citations

• A comprehensive transcriptional portrait of human cancer cell lines

  Christiaan Klijn;Steffen Durinck;Eric W Stawiski;Peter M Haverty

  672
  Citations

• Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

  Kevin M Haigis;Krystle R Kendall;Yufang Wang;Ann Cheung

  660
  Citations

• Oncogene addiction: setting the stage for molecularly targeted cancer therapy

  Sreenath V. Sharma;Jeffrey Settleman

  616
  Citations

• Elevated CRAF as a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma

  Clara Montagut;Sreenath V. Sharma;Toshi Shioda;Ultan McDermott

  605
  Citations

• The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation.

  Kathy Barrett;Maria Leptin;Jeffrey Settleman

  542
  Citations

• p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho

  Gregg A. Wildenberg;Michael R. Dohn;Robert H. Carnahan;Michael A. Davis

  522
  Citations