D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 20,915 271 World Ranking 3964 National Ranking 298

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

His primary scientific interests are in Systems biology, Bioinformatics, Computational biology, Signal transduction and Theoretical computer science. His Systems biology research is multidisciplinary, incorporating perspectives in Software, Fuzzy logic, Artificial intelligence and Machine learning, Profiling. His Bioinformatics study integrates concerns from other disciplines, such as Myeloid, Cancer research, Gateway and Crowdsourcing, World Wide Web.

His Computational biology research includes themes of Benchmarking, Genomics, In silico, Gene and Reverse engineering. His Cell signaling and Protein Interaction Map study, which is part of a larger body of work in Signal transduction, is frequently linked to Protein network and Network topology, bridging the gap between disciplines. His work carried out in the field of Theoretical computer science brings together such families of science as State and Mammalian cell.

His most cited work include:

  • Systematic identification of genomic markers of drug sensitivity in cancer cells (1650 citations)
  • Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients (957 citations)
  • A Landscape of Pharmacogenomic Interactions in Cancer (823 citations)

What are the main themes of his work throughout his whole career to date?

Julio Saez-Rodriguez mostly deals with Computational biology, Cancer, Signal transduction, Systems biology and Bioinformatics. In Computational biology, Julio Saez-Rodriguez works on issues like Pharmacogenomics, which are connected to Drug resistance. Julio Saez-Rodriguez combines topics linked to CRISPR with his work on Cancer.

In his work, Metabolomics is strongly intertwined with Phosphoproteomics, which is a subfield of Signal transduction. His biological study spans a wide range of topics, including Proteome, Software and Theoretical computer science. He has included themes like Carcinogenesis, Receptor and Proteomics in his Cell biology study.

He most often published in these fields:

  • Computational biology (75.11%)
  • Cancer (25.53%)
  • Signal transduction (23.40%)

What were the highlights of his more recent work (between 2020-2021)?

  • Computational biology (75.11%)
  • Transcriptome (16.60%)
  • Cancer research (8.51%)

In recent papers he was focusing on the following fields of study:

His main research concerns Computational biology, Transcriptome, Cancer research, Kidney disease and Metabolomics. His Computational biology research incorporates themes from Cell signaling, Proteomics, Gene and Drug. The Drug study combines topics in areas such as Clinical Oncology, Pharmacogenomics and Mechanism of action.

His study in Transcriptome is interdisciplinary in nature, drawing from both Chromatin, Fibrosis, Myofibroblast and Cellular differentiation. His Cancer research study combines topics in areas such as Carcinogenesis, Gene knockdown, In vivo and Single-cell analysis. His studies deal with areas such as Microbiome, Bioinformatics and Glomerulonephritis as well as Kidney disease.

Between 2020 and 2021, his most popular works were:

  • Decoding myofibroblast origins in human kidney fibrosis (19 citations)
  • Decoding myofibroblast origins in human kidney fibrosis (19 citations)
  • Decoding myofibroblast origins in human kidney fibrosis (19 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

His scientific interests lie mostly in Computational biology, Kidney disease, Metabolomics, Proteome and Proteomics. His Computational biology study frequently draws connections between adjacent fields such as Gene regulatory network. His studies in Kidney disease integrate themes in fields like Cancer research, Fibrosis, Myofibroblast, RNA-Seq and Cellular differentiation.

His work deals with themes such as Cosmos, Multi omics and Phosphoproteomics, which intersect with Metabolomics. The concepts of his Proteome study are interwoven with issues in Internal medicine, Nephrology, Omics and Kidney biopsy sample. His Proteomics research integrates issues from Structural biology, Yeast, Protein aggregation and Phosphorylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman.
Nature (2012)

2279 Citations

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering;Hayley E. Francies;Joshua M. Francis;Joshua M. Francis;Gergana Bounova.
Cell (2015)

1589 Citations

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio;Francesco Iorio;Theo A. Knijnenburg;Theo A. Knijnenburg;Daniel J. Vis;Graham R. Bignell.
Cell (2016)

917 Citations

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

Fiona M. Behan;Francesco Iorio;Francesco Iorio;Gabriele Picco;Emanuel Gonçalves.
Nature (2019)

646 Citations

Structural and functional analysis of cellular networks with CellNetAnalyzer

Steffen Klamt;Julio Saez-Rodriguez;Ernst Dieter Gilles.
BMC Systems Biology (2007)

606 Citations

Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

Robert J. Prill;Daniel Marbach;Julio Saez-Rodriguez;Julio Saez-Rodriguez;Peter Karl Sorger;Peter Karl Sorger.
PLOS ONE (2010)

467 Citations

A methodology for the structural and functional analysis of signaling and regulatory networks

Steffen Klamt;Julio Saez-Rodriguez;Jonathan A. Lindquist;Luca Simeoni.
BMC Bioinformatics (2006)

462 Citations

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis;Hiroko Koike-Yusa;Etienne De Braekeleer;Yilong Li.
Cell Reports (2016)

454 Citations

Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties

Michael P. Menden;Francesco Iorio;Francesco Iorio;Mathew Garnett;Ultan McDermott.
PLOS ONE (2013)

429 Citations

Pharmacogenomic agreement between two cancer cell line data sets

Nicolas Stransky;Mahmoud Ghandi.
Nature (2015)

424 Citations

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