What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Cell biology, Stem cell, Wnt signaling pathway, Cellular differentiation and Immunology.
His Cell biology research focuses on subjects like Crypt, which are linked to Paneth cell.
His Stem cell study combines topics in areas such as Organoid and Adult stem cell.
His work in Wnt signaling pathway is not limited to one particular discipline; it also encompasses Cancer research.
His research investigates the connection between Cellular differentiation and topics such as Single-cell analysis that intersect with problems in Transcriptome.
Within one scientific family, Hans Clevers focuses on topics pertaining to Adenomatous polyposis coli under Beta-catenin, and may sometimes address concerns connected to Tumor suppressor gene.
His most cited work include:
- Wnt/beta-catenin signaling in development and disease. (4369 citations)
- Identification of stem cells in small intestine and colon by marker gene Lgr5 (3702 citations)
- Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. (3440 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Stem cell, Organoid, Wnt signaling pathway and Cancer research.
His studies deal with areas such as Immunology, Intestinal epithelium, Cellular differentiation and Genetics as well as Cell biology.
His studies in Stem cell integrate themes in fields like Endothelial stem cell and Adult stem cell.
The Organoid study combines topics in areas such as Epithelium, Pathology, CRISPR, Internal medicine and Personalized medicine.
Hans Clevers studied Wnt signaling pathway and Molecular biology that intersect with Gene, Gene expression and Enhancer.
The concepts of his Cancer research study are interwoven with issues in Carcinogenesis, Cancer and Colorectal cancer.
He most often published in these fields:
- Cell biology (42.09%)
- Stem cell (32.94%)
- Organoid (26.38%)
What were the highlights of his more recent work (between 2018-2021)?
- Organoid (26.38%)
- Cell biology (42.09%)
- Cancer research (22.27%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Organoid, Cell biology, Cancer research, Stem cell and Cancer.
His biological study spans a wide range of topics, including CRISPR, Adult stem cell, Internal medicine, Personalized medicine and Computational biology.
The Cell biology study which covers Cellular differentiation that intersects with Cell.
His Cancer research study also includes fields such as
- Colorectal cancer which connect with Metastasis,
- Transplantation which intersects with area such as PTEN.
His Stem cell research is multidisciplinary, incorporating perspectives in Tissue engineering, Crypt and Cell type.
His Cancer research includes themes of Epithelium, Immune system, Oncology and Genetic heterogeneity.
Between 2018 and 2021, his most popular works were:
- SARS-CoV-2 productively infects human gut enterocytes. (576 citations)
- Tales from the crypt: new insights into intestinal stem cells. (206 citations)
- Tales from the crypt: new insights into intestinal stem cells. (206 citations)
In his most recent research, the most cited papers focused on:
Hans Clevers focuses on Organoid, Cell biology, Stem cell, Cancer and Cancer research.
His work deals with themes such as Epithelium, CRISPR, Cystic fibrosis, Personalized medicine and Computational biology, which intersect with Organoid.
His Cell biology study integrates concerns from other disciplines, such as Transcriptome and Cellular differentiation, Adult stem cell.
His research integrates issues of Crypt, Transcription factor and Cell type in his study of Stem cell.
His Homeostasis research includes elements of Cell, Wnt signaling pathway and Immune system.
His Wnt signaling pathway research integrates issues from Paneth cell and Flow cytometry.
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