World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
68402
World Ranking
4423
National Ranking
14

Nick Barker publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Nick Barker sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 136 publications — 20th percentile

20% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Nick Barker D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Nick Barker sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 78 D-Index — 77th percentile

77% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Nick Barker is affiliated with the Agency for Science, Technology and Research in Singapore. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on molecular biology, oncology, surgery, genetics, and pulmonary and respiratory medicine. The scientist's work primarily addresses topics related to cancer cells and metastasis, digestive system health, pluripotent stem cells research, epigenetics and DNA methylation, Helicobacter pylori-related gastroenterology studies, cancer genomics and diagnostics, and gut microbiota and health.

Notable papers authored by Nick Barker include:

  • Cell transcriptomic atlas of the non-human primate Macaca fascicularis, 2022, Nature
  • AQP5 enriches for stem cells and cancer origins in the distal stomach, 2020, Nature
  • A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers, 2021, Nature Cell Biology
  • A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis, 2021, Cell Reports
  • A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells, 2021, Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Nick Barker are:

  • Hui Yi Grace Lim
  • Swathi Yada
  • Kazuhiro Murakami
  • Sowmya Sagiraju
  • Bernett Lee

Nick Barker's research has appeared in multiple publication venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Cancer
  • Gastroenterology
  • Nature

Best Publications

  • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

    Toshiro Sato;Robert G J Vries;Hugo J. Snippert;Marc van de Wetering

  • Identification of stem cells in small intestine and colon by marker gene Lgr5

    Nick Barker;Johan H. van Es;Jeroen Kuipers;Pekka Kujala

  • Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

    Patrice J. Morin;Andrew B. Sparks;Vladimir Korinek;Nick Barker

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Kerstin Howe;Matthew D. Clark;Carlos F. Torroja;Carlos F. Torroja;James Torrance

  • Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma

    Vladimir Korinek;Nick Barker;Patrice J. Morin;Dick van Wichen

  • Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

    Toshiro Sato;Johan H. van Es;Hugo J. Snippert;Daniel E. Stange

  • Crypt stem cells as the cells-of-origin of intestinal cancer

    Nick Barker;Rachel A. Ridgway;Johan H. Van Es;Marc Van De Wetering

  • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

    Hugo J. Snippert;Laurens G. van der Flier;Toshiro Sato;Johan H. van Es

  • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.

    V Korinek;N Barker;P Moerer;E van Donselaar

  • Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

    Nick Barker;Meritxell Huch;Pekka Kujala;Marc van de Wetering

  • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

    Wim De Lau;Nick Barker;Nick Barker;Teck Y. Low;Bon Kyoung Koo

  • Organoids as an in vitro model of human development and disease

    Aliya Fatehullah;Si Hui Tan;Nick Barker;Nick Barker;Nick Barker

  • Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

    Nick Barker

  • Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

    Sarah Schwitalla;Alexander A. Fingerle;Patrizia Cammareri;Tim Nebelsiek

  • Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

    Viljar Jaks;Nick Barker;Maria Kasper;Johan H. van Es

  • Mining the Wnt pathway for cancer therapeutics

    Nick Barker;Hans Clevers

  • Functional interaction between beta-catenin and FOXO in oxidative stress signaling.

    Marieke A. G. Essers;Lydia M. M. de Vries-Smits;Nick Barker;Paulien E. Polderman

  • Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

    Hugo J. G. Snippert;Andrea Haegebarth;Maria Kasper;Viljar Jaks

  • Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

    Johan H. van Es;Toshiro Sato;Marc van de Wetering;Anna Lyubimova

  • The intestinal stem cell

    Nick Barker;Marc van de Wetering;Hans Clevers

Frequent Co-Authors

Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Owen J. Sansom
Owen J. Sansom University of Glasgow
Johan H. van Es
Johan H. van Es Utrecht University
Marc van de Wetering
Marc van de Wetering Royal Netherlands Academy of Arts and Sciences
Peter J. Peters
Peter J. Peters Maastricht University
Daniel K. Podolsky
Daniel K. Podolsky The University of Texas at Dallas
Toshiro Sato
Toshiro Sato Keio University
Rune Toftgård
Rune Toftgård Karolinska Institute
Alexander van Oudenaarden
Alexander van Oudenaarden University Medical Center Utrecht
Irene M. Leigh
Irene M. Leigh University of Dundee

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