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Molecular Biology
Netherlands
2026

D-Index & Metrics

Molecular Biology

D-Index
118
Citations
70422
World Ranking
275
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Netherlands Leader Award
  • 2025 - Research.com Molecular Biology in Netherlands Leader Award
  • 2023 - Research.com Molecular Biology in Netherlands Leader Award
  • 2017 - Spinoza Prize, Dutch Research Council
  • 2014 - Royal Netherlands Academy of Arts and Sciences
  • 2008 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2008 - National Institutes of Health Director's Pioneer Award
  • 2001 - Fellow of Alfred P. Sloan Foundation
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Alexander van Oudenaarden is affiliated with the University Medical Center Utrecht in the Netherlands. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Genetics, Surgery, Cancer Research, and Oncology as subfields.

The scientist's work extensively covers topics including:

  • Single-cell and spatial transcriptomics
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Pluripotent Stem Cells Research
  • RNA Research and Splicing
  • DNA Repair Mechanisms

Alexander van Oudenaarden has published multiple papers in prominent journals. Notable recent publications include:

  • An in vitro model of early anteroposterior organization during human development, 2020, Nature
  • Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids, 2020, Nature
  • High-throughput total RNA sequencing in single cells using VASA-seq, 2022, Nature Biotechnology
  • LifeTime and improving European healthcare through cell-based interceptive medicine, 2020, Nature
  • Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies, 2020, Science

The main venues for publishing their research include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 18 publications
  • Nature with 6 publications
  • Nature Biotechnology with 3 publications
  • Nature Methods with 3 publications
  • Nature Communications with 3 publications

Frequent collaborators in their research include:

  • Peter Zeller
  • Jeroen van den Berg
  • Vincent van Batenburg
  • Buys de Barbanson
  • Michael VanInsberghe

The scientist has received several awards throughout their career, such as the Spinoza Prize from the Dutch Research Council in 2017, and membership in distinguished organizations including the Royal Netherlands Academy of Arts and Sciences (2014), the European Molecular Biology Organization (EMBO), and fellowships from the John Simon Guggenheim Memorial Foundation (2008) and the Alfred P. Sloan Foundation (2001). Additionally, they have been honored with the National Institutes of Health Director's Pioneer Award in 2008.

Best Publications

  • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

    Ahmad M. Khalil;Mitchell Guttman;Maite Huarte;Manuel Garber

  • Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

    Arjun Raj;Alexander van Oudenaarden

  • Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

    Marc van de Wetering;Hayley E. Francies;Joshua M. Francis;Joshua M. Francis;Gergana Bounova

  • IMAGING INDIVIDUAL mRNA MOLECULES USING MULTIPLE SINGLY LABELED PROBES

    Arjun Raj;Sanjay Tyagi

  • Regulation of noise in the expression of a single gene

    Ertugrul M. Ozbudak;Mukund Thattai;Iren Kurtser;Alan D. Grossman

  • Intrinsic noise in gene regulatory networks

    Mukund Thattai;Alexander van Oudenaarden

  • Population genomics of domestic and wild yeasts

    Gianni Liti;David M. Carter;Alan M. Moses;Alan M. Moses;Jonas Warringer

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Multistability in the lactose utilization network of Escherichia coli

    Ertugrul M. Ozbudak;Mukund Thattai;Han N. Lim;Boris I. Shraiman

  • Single-cell messenger RNA sequencing reveals rare intestinal cell types

    Dominic Grün;Dominic Grün;Anna Lyubimova;Anna Lyubimova;Lennart Kester;Lennart Kester;Kay Wiebrands;Kay Wiebrands

  • Direct cell reprogramming is a stochastic process amenable to acceleration

    Jacob Hanna;Krishanu Saha;Bernardo Pando;Jeroen van Zon

  • A Single-Cell Transcriptome Atlas of the Human Pancreas

    Mauro J. Muraro;Gitanjali Dharmadhikari;Dominic Grün;Dominic Grün;Nathalie Groen

  • Cellular decision making and biological noise: from microbes to mammals.

    Gábor Balázsi;Alexander van Oudenaarden;James J. Collins;James J. Collins

  • Stochastic switching as a survival strategy in fluctuating environments.

    Murat Acar;Jerome T Mettetal;Alexander van Oudenaarden

  • Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

    Wenjun Guo;Zuzana Keckesova;Joana Liu Donaher;Tsukasa Shibue

  • Noise Propagation in Gene Networks

    Juan M. Pedraza;Alexander van Oudenaarden

  • Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

    Yosef Buganim;Dina A. Faddah;Albert W. Cheng;Elena Itskovich

  • Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations

    Susanne Carina Van den Brink;Fanny Sage;Ábel Vértesy;Bastiaan Spanjaard;Bastiaan Spanjaard

  • MicroRNA-mediated Feedback and Feedforward Loops are Recurrent Network Motifs in Mammals

    John Tsang;John Tsang;Jun Zhu;Alexander van Oudenaarden

  • Population genomics of domestic and wild yeasts

    David M. Carter;Gianni Liti;Alan M. Moses;Leopold Parts

Frequent Co-Authors

Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Dominic Grün
Dominic Grün Max Planck Society
John C. Marioni
John C. Marioni European Bioinformatics Institute
Wolf Reik
Wolf Reik Babraham Institute
Shalev Itzkovitz
Shalev Itzkovitz Weizmann Institute of Science
Marc van de Wetering
Marc van de Wetering Royal Netherlands Academy of Arts and Sciences
Johan H. van Es
Johan H. van Es Utrecht University
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Aviv Regev
Aviv Regev Genentech
Eric S. Lander
Eric S. Lander Broad Institute

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