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Hiroshi Hirota

Hiroshi Hirota

D-Index & Metrics

Chemistry

D-Index
55
Citations
8450
World Ranking
12389
National Ranking
930

Overview

Hiroshi Hirota is affiliated with Nihon University in Japan and conducts research primarily within the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Agricultural and Biological Sciences. Their work intersects multiple subfields including Plant Science, Pharmacology, Molecular Biology, Materials Chemistry, and Cell Biology.

Their scholarly contributions focus on several main topics:

  • Microbial Natural Products and Biosynthesis
  • Insect Resistance and Genetics
  • Fungal Biology and Applications
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Mycotoxins in Agriculture and Food
  • Nuclear reactor physics and engineering

Hirota has published articles across various venues, most notably in Bioscience Biotechnology and Biochemistry with two publications, as well as contributions in Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms and the Journal of Natural Medicines.

Selected recent papers include the following:

  • "Biosynthetic gene cluster identification and biological activity of lucilactaene from Fusarium sp. RK97-94," 2020, published in Bioscience Biotechnology and Biochemistry
  • "Controlling the production of phytotoxin pyriculol in Pyricularia oryzae by aldehyde reductase," 2021, published in Bioscience Biotechnology and Biochemistry
  • "Characterization of mineral insulated cables at the WWR-K reactor: First results," 2024, published in Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms
  • "Grandifolins A-D: three 6/6/5 abietane diterpenes and an abietane diterpene from Salvia grandifolia," 2025, published in Journal of Natural Medicines

Frequent co-authors collaborating with Hirota include Takayuki Motoyama, Toshihiko Nogawa, Takashi Kamakura, Hiroyuki Osada, and Sho Kato, each having coauthored multiple works with Hirota.

Best Publications

  • Structural genomics projects in Japan.

    Shigeyuki Yokoyama;Hiroshi Hirota;Takanori Kigawa;Takashi Yabuki

  • Notoamides A–D: Prenylated Indole Alkaloids Isolated from a Marine‐Derived Fungus, Aspergillus sp.

    Hikaru Kato;Takushi Yoshida;Takanori Tokue;Yuka Nojiri

  • Zinc suppresses Th17 development via inhibition of STAT3 activation.

    Chika Kitabayashi;Toshiyuki Fukada;Minoru Kanamoto;Wakana Ohashi

  • Evaluations of molecular docking programs for virtual screening.

    Kenji Onodera;Kazuhito Satou;Hiroshi Hirota

  • Haliclamines A and B, cytotoxic macrocyclic alkaloids from a sponge of the genus Haliclona

    N. Fusetani;K. Yasumuro;S. Matsunaga;H. Hirota

  • Bioactive marine metabolites. Part 35. Cytotoxic metabolites of the marine sponge Mycale adhaerens Lambe

    Nobuhiro Fusetani;Takeo Sugawara;Shigeki Matsunaga;Hiroshi Hirota

  • Terpenoids with antifouling activity against barnacle larvae from the marine sponge Acanthella cavernosa

    Hiroshi Hirota;Yasuhiko Tomono;Nobuhiro Fusetani

  • Ceratinamides A and B: New Antifouling Dibromotyrosine Derivatives from the Marine Sponge Pseudoceratina purpurea

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • Isolation of antipodal (-)-versicolamide B and notoamides L-N from a marine-derived Aspergillus sp

    Sachiko Tsukamoto;Tetsuro Kawabata;Hikaru Kato;Thomas J. Greshock

  • Notoamides F-K, prenylated indole alkaloids isolated from a marine-derived Aspergillus sp.

    Sachiko Tsukamoto;Hikaru Kato;Masayuki Samizo;Yuka Nojiri

  • Orbiculamide A: a novel cytotoxic cyclic peptide from a marine sponge Theonella sp

    Nobuhiro Fusetani;Takeo Sugawara;Shigeki Matsunaga;Hiroshi Hirota

  • Gambieric acids: unprecedented potent antifungal substances isolated from cultures of a marine dinoflagellate Gambierdiscus toxicus

    Hiroshi Nagai;Koichiro Torigoe;Masayuki Satake;Michio Murata

  • Mauritiamine, a new antifouling oroidin dimer from the marine sponge Agelas mauritiana

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • New antifouling sesquiterpenes from four nudibranchs of the family Phyllidiidae

    Tatsufumi Okino;Erina Yoshimura;Hiroshi Hirota;Nobuhiro Fusetani

  • Notoamide O, a Structurally Unprecedented Prenylated Indole Alkaloid, and Notoamides P−R from a Marine-Derived Fungus, Aspergillus sp.

    Sachiko Tsukamoto;Hideharu Umaoka;Kohei Yoshikawa;Tsuyoshi Ikeda

  • Antifouling kalihinenes from the marine sponge Acanthella cavernosa

    Tatsufumi Okino;Erina Yoshimura;Hiroshi Hirota;Nobuhiro Fusetani

  • Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge

    Toshiyuki Hamada;Shigeki Matsunaga;Masako Fujiwara;Kenichi Fujita

  • Five new antifouling sesquiterpenes from two marine sponges of the genus Axinyssa and the nudibranch Phyllidia pustulosa

    Hiroshi Hirota;Tatsufumi Okino;Erina Yoshimura;Nobuhiro Fusetani

  • Solution Structure of the SEA Domain from the Murine Homologue of Ovarian Cancer Antigen CA125 (MUC16)

    Takeshi Maeda;Makoto Inoue;Seizo Koshiba;Takashi Yabuki

  • Aurantosides A and B: cytotoxic tetramic acid glycosides from the marine sponge Theonella sp

    Shigeki Matsunaga;Nobuhiro Fusetani;Yuko Kato;Hiroshi Hirota

  • Structural genomics projects in Japan.

    Shigeyuki Yokoyama;Yo Matsuo;Hiroshi Hirota;Takanori Kigawa

Frequent Co-Authors

Nobuhiro Fusetani
Nobuhiro Fusetani Waseda University
Sachiko Tsukamoto
Sachiko Tsukamoto Kumamoto University
Masami Ishibashi
Masami Ishibashi Chiba University
Hiroyuki Koshino
Hiroyuki Koshino Tokyo University of Agriculture
Mikako Shirouzu
Mikako Shirouzu RIKEN Center for Biosystems Dynamics Research
Takanori Kigawa
Takanori Kigawa RIKEN Center for Biosystems Dynamics Research
Akira Isogai
Akira Isogai University of Tokyo
Takaho Terada
Takaho Terada University of Tokyo

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