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Biology and Biochemistry

D-Index
85
Citations
26677
World Ranking
3144
National Ranking
1590

Overview

David H. Sherman is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple fields, with a primary focus on biochemistry, genetics, and molecular biology, supported by substantial work in medicine.

Within these disciplines, Sherman's work covers several subfields, including pharmacology, molecular biology, organic chemistry, biotechnology, and materials chemistry. The research topics are diverse but show a concentration on microbial natural products and biosynthesis. Additional topics include genomics and phylogenetic studies, alkaloids synthesis and pharmacology, aquatic ecosystems and phytoplankton dynamics, chemical synthesis related to alkaloids, pharmacogenetics, drug metabolism, and marine sponges and natural products.

Their recent papers reflect this breadth of study and were published in notable venues from 2020 to 2022:

  • Fungal-derived brevianamide assembly by a stereoselective semipinacolase, 2020, Nature Catalysis
  • Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase, 2020, Journal of the American Chemical Society
  • Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway, 2020, Journal of the American Chemical Society
  • Metagenomic and Metatranscriptomic Insights into Population Diversity of Microcystis Blooms: Spatial and Temporal Dynamics of mcy Genotypes, Including a Partial Operon That Can Be Abundant and Expressed, 2022, Applied and Environmental Microbiology
  • Chemoenzymatic synthesis of fluorinated polyketides, 2022, Nature Chemistry

Frequent co-authors in Sherman's publications include:

  • Sean A. Newmister (21 coauthored works)
  • Jennifer J. Schmidt (14 coauthored works)
  • K. N. Houk (11 coauthored works)
  • Ashootosh Tripathi (11 coauthored works)
  • Andrew N. Lowell (11 coauthored works)

Sherman's publications appear regularly in several key scientific venues, such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 10 publications
  • ACS Catalysis with 7 publications
  • Journal of the American Chemical Society with 5 publications
  • The Cambridge Structural Database with 5 publications
  • Phytochemistry Letters with 5 publications

Best Publications

  • A putative flip–flop switch for control of REM sleep

    Jun Lu;David Sherman;Marshall Devor;Marshall Devor;Clifford B. Saper

  • Molecular Genetics of Polyketides and Its Comparison to Fatty Acid Biosynthesis

    David A. Hopwood;David H. Sherman;David H. Sherman

  • A genomic catalog of Earth’s microbiomes

    Stephen Nayfach;Simon Roux;Rekha Seshadri;Daniel Udwary

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Reassessment of the structural basis of the ascending arousal system.

    Patrick M. Fuller;David Sherman;Nigel P. Pedersen;Clifford B. Saper

  • A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity

    Yongquan Xue;Lishan Zhao;Hung Wen Liu;David H. Sherman

  • Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina

    Sebastian Sudek;Nicole B. Lopanik;Laura E. Waggoner;Mark Hildebrand

  • Structure of a modular polyketide synthase

    Somnath Dutta;Jonathan R. Whicher;Douglas A. Hansen;Wendi A. Hale

  • Biosynthetic Pathway and Gene Cluster Analysis of Curacin A, an Antitubulin Natural Product from the Tropical Marine Cyanobacterium Lyngbya majuscula†

    Zunxue Chang;Namthip Sitachitta;James V. Rossi;Mary Ann Roberts

  • Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites

    Nathan A. Magarvey;Jessica M. Keller;Valerie Bernan;Martin Dworkin

  • Enantiomeric natural products: occurrence and biogenesis.

    Jennifer M. Finefield;David H. Sherman;Martin Kreitman;Robert M. Williams;Robert M. Williams

  • The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

    Zunxue Chang;Patricia Flatt;William H. Gerwick;Viet Anh Nguyen

  • Automated genome mining for natural products

    Michael H. T. Li;Peter M. U. Ung;James Zajkowski;Sylvie Garneau-Tsodikova

  • Diversity of P450 enzymes in the biosynthesis of natural products.

    Larissa M. Podust;David H. Sherman

  • Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

    D.H. Sherman;F. Malpartida;M.J. Bibb;H.M. Kieser

  • Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743

    Christopher M. Rath;Benjamin Janto;Josh Earl;Azad Ahmed

  • Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564

    Yingqing Mao;Mustafa Varoglu;David H Sherman

  • Structural rearrangements of a polyketide synthase module during its catalytic cycle.

    Jonathan R. Whicher;Somnath Dutta;Douglas A. Hansen;Wendi A. Hale

  • Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery

    Christine E. Salomon;Nathan A. Magarvey;David H. Sherman

  • Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera

    David M. Kranz;David H. Sherman;Michail V. Sitkovsky;Mark S. Pasternack

Frequent Co-Authors

Robert M. Williams
Robert M. Williams Colorado State University
Janet L. Smith
Janet L. Smith University of Michigan–Ann Arbor
William H. Gerwick
William H. Gerwick University of California, San Diego
Sachiko Tsukamoto
Sachiko Tsukamoto Kumamoto University
Wei Shou Hu
Wei Shou Hu University of Minnesota
Philip C. Hanna
Philip C. Hanna University of Michigan–Ann Arbor
Hung-wen Liu
Hung-wen Liu The University of Texas at Austin
David A. Hopwood
David A. Hopwood John Innes Centre
John Montgomery
John Montgomery University of Michigan–Ann Arbor
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles

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