David H. Sherman mostly deals with Biochemistry, Stereochemistry, Polyketide, Polyketide synthase and Biosynthesis. His Stereochemistry study combines topics in areas such as Reductase, Active site, Decarboxylation, Pikromycin and Binding site. His Polyketide research includes elements of Nonribosomal peptide, Docking, Natural product, Secondary metabolism and Acyl carrier protein.
The concepts of his Polyketide synthase study are interwoven with issues in Bryostatin, Gene product, ATP synthase and Streptomyces. His research in Streptomyces intersects with topics in Rhizobium, Escherichia coli, ORFS, Open reading frame and Chalcone synthase. His work carried out in the field of Biosynthesis brings together such families of science as Lyngbya majuscula, Cyanobacteria, Fatty acid, Indole test and Prenylation.
His primary scientific interests are in Stereochemistry, Biochemistry, Polyketide, Biosynthesis and Polyketide synthase. His Stereochemistry study which covers Pikromycin that intersects with Desosamine. His work in Biochemistry tackles topics such as Streptomyces which are related to areas like Open reading frame.
His work deals with themes such as Nonribosomal peptide, Streptomyces coelicolor, Acyltransferase, Computational biology and ATP synthase, which intersect with Polyketide. His Biosynthesis study frequently draws connections to adjacent fields such as Metabolic pathway. His studies in Polyketide synthase integrate themes in fields like Decarboxylation, Transferase and Acyl carrier protein.
David H. Sherman spends much of his time researching Stereochemistry, Biosynthesis, Polyketide, Biochemistry and Polyketide synthase. His biological study spans a wide range of topics, including Acyl carrier protein, Cycloaddition and Substrate, Enzyme. His study in Biosynthesis is interdisciplinary in nature, drawing from both Monooxygenase, Molecule, Flavin group, Operon and Bacillus anthracis.
The various areas that David H. Sherman examines in his Polyketide study include Protein domain, Active site, Protein structure, Selectivity and Computational biology. As part of his studies on Biochemistry, David H. Sherman often connects relevant areas like Streptomyces. His Polyketide synthase research incorporates elements of Gene cluster, Acyltransferase, Lyase and Transferase.
David H. Sherman mainly investigates Stereochemistry, Polyketide, Biosynthesis, Biochemistry and Polyketide synthase. His work on Indole test as part of general Stereochemistry research is often related to Extender, thus linking different fields of science. The study incorporates disciplines such as Protein domain, Mutant, Synthetic biology, Gene cluster and Acyltransferase in addition to Polyketide.
The Mutant study combines topics in areas such as Protein phosphatase 2, Streptomyces and Thioesterase. His research on Biosynthesis frequently links to adjacent areas such as Carbon-Carbon Lyases. As part of his studies on Polyketide synthase, David H. Sherman frequently links adjacent subjects like Lyase.
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A putative flip–flop switch for control of REM sleep
Jun Lu;David Sherman;Marshall Devor;Marshall Devor;Clifford B. Saper.
Nature (2006)
Molecular Genetics of Polyketides and Its Comparison to Fatty Acid Biosynthesis
David A. Hopwood;David H. Sherman;David H. Sherman.
Annual Review of Genetics (1990)
Minimum Information about a Biosynthetic Gene cluster.
Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings.
Nature Chemical Biology (2015)
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity
Yongquan Xue;Lishan Zhao;Hung Wen Liu;David H. Sherman.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Reassessment of the structural basis of the ascending arousal system.
Patrick M. Fuller;David Sherman;Nigel P. Pedersen;Clifford B. Saper.
The Journal of Comparative Neurology (2011)
Identification of the putative bryostatin polyketide synthase gene cluster from "Candidatus Endobugula sertula", the uncultivated microbial symbiont of the marine bryozoan Bugula neritina
Sebastian Sudek;Nicole B. Lopanik;Laura E. Waggoner;Mark Hildebrand.
Journal of Natural Products (2007)
Biosynthetic Pathway and Gene Cluster Analysis of Curacin A, an Antitubulin Natural Product from the Tropical Marine Cyanobacterium Lyngbya majuscula†
Zunxue Chang;Namthip Sitachitta;James V. Rossi;Mary Ann Roberts.
Journal of Natural Products (2004)
Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites
Nathan A. Magarvey;Jessica M. Keller;Valerie Bernan;Martin Dworkin.
Applied and Environmental Microbiology (2004)
The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit
Zunxue Chang;Patricia Flatt;William H. Gerwick;Viet Anh Nguyen.
Gene (2002)
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.
D.H. Sherman;F. Malpartida;M.J. Bibb;H.M. Kieser.
The EMBO Journal (1989)
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