D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 57 Citations 9,465 184 World Ranking 7808 National Ranking 2357

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of study are Stereochemistry, Biochemistry, Biosynthesis, Enzyme and Gene cluster. His Stereochemistry research incorporates themes from Cycloaddition, Catalysis, Fosfomycin, Streptomyces and Methymycin. His study in Glycosyltransferase, Glycosylation, Streptomyces venezuelae, Sugar and Substrate falls within the category of Biochemistry.

His research in Biosynthesis intersects with topics in Terpenoid, Terpene and Reaction mechanism. Nucleotide sugar is closely connected to Natural product in his research, which is encompassed under the umbrella topic of Enzyme. His studies deal with areas such as Polyketide synthase and Sequence analysis as well as Gene cluster.

His most cited work include:

  • A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity (314 citations)
  • Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification (269 citations)
  • Unusual sugar biosynthesis and natural product glycodiversification (228 citations)

What are the main themes of his work throughout his whole career to date?

Hung-wen Liu focuses on Stereochemistry, Biochemistry, Enzyme, Biosynthesis and Substrate. His Stereochemistry study integrates concerns from other disciplines, such as Desosamine, Cofactor and Organic chemistry, Catalysis, Active site. His study in Cofactor is interdisciplinary in nature, drawing from both NAD+ kinase and Flavin group.

His Biochemistry study frequently draws parallels with other fields, such as Streptomyces. His work on Enzyme is being expanded to include thematically relevant topics such as Natural product. His Biosynthesis study combines topics in areas such as Deoxygenation and Methyltransferase.

He most often published in these fields:

  • Stereochemistry (63.74%)
  • Biochemistry (45.04%)
  • Enzyme (42.75%)

What were the highlights of his more recent work (between 2013-2021)?

  • Stereochemistry (63.74%)
  • Biosynthesis (40.84%)
  • Biochemistry (45.04%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Stereochemistry, Biosynthesis, Biochemistry, Enzyme and Substrate. The Stereochemistry study combines topics in areas such as Enzyme catalysis, Cycloaddition, Catalysis, Polyketide and Radical SAM. The study incorporates disciplines such as Gene cluster, Nucleoside, Protein structure, Methyltransferase and Streptomyces in addition to Biosynthesis.

Hung-wen Liu performs multidisciplinary study in the fields of Biochemistry and Glycan via his papers. His work on Intramolecular Lyases as part of general Enzyme study is frequently linked to Natural, bridging the gap between disciplines. His studies in Substrate integrate themes in fields like Stereoisomerism, Dehydrogenation, Deamination, Active site and Fucose.

Between 2013 and 2021, his most popular works were:

  • The structure of SpnF a standalone enzyme that catalyzes [4 + 2] cycloaddition (74 citations)
  • Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides (64 citations)
  • Dynamically Complex [6+4] and [4+2] Cycloadditions in the Biosynthesis of Spinosyn A (62 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Organic chemistry

The scientist’s investigation covers issues in Stereochemistry, Biosynthesis, Enzyme, Cycloaddition and Biochemistry. His Stereochemistry research integrates issues from Catalysis and Substrate. His work carried out in the field of Catalysis brings together such families of science as Natural product, Redox and Chemical reaction.

His Biosynthesis research is multidisciplinary, incorporating elements of Protein structure, Gene cluster and Streptomyces. In general Enzyme study, his work on Radical SAM and Intramolecular Lyases often relates to the realm of Natural and Chaperonin 60, thereby connecting several areas of interest. His Cycloaddition study combines topics from a wide range of disciplines, such as Adduct, Computational chemistry, Intramolecular force and Crystal structure.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity

Yongquan Xue;Lishan Zhao;Hung Wen Liu;David H. Sherman.
Proceedings of the National Academy of Sciences of the United States of America (1998)

477 Citations

Natural-Product Sugar Biosynthesis and Enzymatic Glycodiversification

Christopher J. Thibodeaux;Charles E. Melançon;Hung-Wen Liu.
Angewandte Chemie (2008)

395 Citations

Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria.

Hung Wen Liu;Jon S. Thorson.
Annual Review of Microbiology (1994)

349 Citations

Unusual sugar biosynthesis and natural product glycodiversification

Christopher J. Thibodeaux;Charles E. Melançon;Hung Wen Liu.
Nature (2007)

326 Citations

Formation of cyanide from carbon 1 of 1-aminocyclopropane-1-carboxylic acid during its conversion to ethylene.

Galen D. Peiser;Tsu-Tsuen Wang;Neil E. Hoffman;Shang Fa Yang.
Proceedings of the National Academy of Sciences of the United States of America (1984)

320 Citations

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A

Hak Joong Kim;Mark W. Ruszczycky;Sei Hyun Choi;Yung Nan Liu.
Nature (2011)

289 Citations

Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis

Lishan Zhao;Wei Chen Chang;Youli Xiao;Hung Wen Liu.
Annual Review of Biochemistry (2013)

244 Citations

Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.

Christopher J. Thibodeaux;Wei Chen Chang;Hung-Wen Liu.
Chemical Reviews (2012)

228 Citations

Formation of unusual sugars: mechanistic studies and biosynthetic applications.

Xuemei M. He;Hung-Wen Liu.
Annual Review of Biochemistry (2002)

207 Citations

Identification of the ADP-ribosylation sites in the PARP-1 automodification domain: analysis and implications.

Zhihua Tao;Peng Gao;Hung Wen Liu.
Journal of the American Chemical Society (2009)

187 Citations

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