D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 7,602 139 World Ranking 10744 National Ranking 204

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Bacteria

His primary scientific interests are in Biochemistry, Biosynthesis, Gene, Gene cluster and Streptomyces albus. As part of his studies on Biochemistry, Alfredo F. Braña often connects relevant subjects like Stereochemistry. His Biosynthesis research is multidisciplinary, incorporating elements of Fermentation, Cyclase, Ammonium chloride, Ammonium and Isopenicillin N epimerase.

Alfredo F. Braña works mostly in the field of Gene, limiting it down to concerns involving Streptomyces and, occasionally, Mycelium and Substrate. He interconnects Regulator gene, Streptomyces griseus and Sequence analysis in the investigation of issues within Gene cluster. His study in Streptomyces albus is interdisciplinary in nature, drawing from both Indolocarbazole and Heterologous expression.

His most cited work include:

  • Combinatorial biosynthesis of antitumor indolocarbazole compounds (192 citations)
  • The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin: Characterization and Generation of Indolocarbazole Derivatives (177 citations)
  • Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin (168 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Biosynthesis, Streptomyces, Gene and Gene cluster. Alfredo F. Braña has researched Biochemistry in several fields, including Stereochemistry and Streptomyces albus. The Stereochemistry study combines topics in areas such as Substrate and Aureolic acid.

The concepts of his Biosynthesis study are interwoven with issues in Glycosylation and Streptomyces griseus. His Streptomyces study incorporates themes from Botany, Enterobactin, Microbiology and Polysaccharide. He combines subjects such as Streptomyces cattleya, Thienamycin, Regulator gene and Sequence analysis with his study of Gene cluster.

He most often published in these fields:

  • Biochemistry (70.21%)
  • Biosynthesis (46.10%)
  • Streptomyces (43.97%)

What were the highlights of his more recent work (between 2015-2020)?

  • Streptomyces (43.97%)
  • Biochemistry (70.21%)
  • Biosynthesis (46.10%)

In recent papers he was focusing on the following fields of study:

Streptomyces, Biochemistry, Biosynthesis, Gene and Gene cluster are his primary areas of study. His Streptomyces research incorporates elements of Botany, Glycosyltransferase and Microbiology. Biochemistry and Streptomyces albus are commonly linked in his work.

The various areas that Alfredo F. Braña examines in his Biosynthesis study include Oxidoreductase, Oxazole, Thiazole, Stereochemistry and Leinamycin. His Gene study results in a more complete grasp of Genetics. In his study, Hypothetical protein is strongly linked to Polyketide, which falls under the umbrella field of Gene cluster.

Between 2015 and 2020, his most popular works were:

  • Branimycins B and C, Antibiotics Produced by the Abyssal Actinobacterium Pseudonocardia carboxydivorans M-227 (23 citations)
  • Lobophorin K, a New Natural Product with Cytotoxic Activity Produced by Streptomyces sp. M-207 Associated with the Deep-Sea Coral Lophelia pertusa (22 citations)
  • New insights into paulomycin biosynthesis pathway in Streptomyces albus J1074 and generation of novel derivatives by combinatorial biosynthesis (21 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Bacteria

His scientific interests lie mostly in Streptomyces, Gene, Gene cluster, Genome and Heterologous expression. His Streptomyces research integrates issues from Glycosyltransferase, Metabolic engineering, Pyruvate dehydrogenase complex and Enzyme. His studies deal with areas such as Structural similarity and DNA as well as Gene.

His study with Gene cluster involves better knowledge in Biochemistry. His research integrates issues of Regulation of gene expression, Regulator gene and Oligonucleotide in his study of Genome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Combinatorial biosynthesis of antitumor indolocarbazole compounds

César Sánchez;Lili Zhu;Alfredo F. Braña;Aaroa P. Salas.
Proceedings of the National Academy of Sciences of the United States of America (2005)

284 Citations

The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin: Characterization and Generation of Indolocarbazole Derivatives

César Sánchez;Igor A Butovich;Alfredo F Braña;Jürgen Rohr.
Chemistry & Biology (2002)

249 Citations

Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

Ernestina Fernández;Ulrike Weißbach;César Sánchez Reillo;Alfredo F. Braña.
Journal of Bacteriology (1998)

213 Citations

Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two Streptomyces species

Felipe Lombó;Ana Velasco;Angelina Castro;Fernando de la Calle.
ChemBioChem (2006)

207 Citations

Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.

Lily L. Remsing;Ana M. González;Mohammad Nur-e-Alam;M. José Fernández-Lozano.
Journal of the American Chemical Society (2003)

177 Citations

Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055: Cluster Analysis and Assignment of Functions

Carlos Olano;Barrie Wilkinson;César Sánchez;Steven J Moss.
Chemistry & Biology (2004)

176 Citations

Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074

Carlos Olano;Ignacio García;Aranzazu González;Miriam Rodriguez.
Microbial Biotechnology (2014)

168 Citations

Engineering Deoxysugar Biosynthetic Pathways from Antibiotic-Producing Microorganisms: A Tool to Produce Novel Glycosylated Bioactive Compounds

Leticia Rodrı́guez;Ignacio Aguirrezabalaga;Nerea Allende;Alfredo F Braña.
Chemistry & Biology (2002)

161 Citations

Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine : sugar donor substrate flexibility of the StaG glycosyltransferase

Aaroa P. Salas;Lili Zhu;César Sánchez;Alfredo F. Braña.
Molecular Microbiology (2005)

144 Citations

Reevaluation of the violacein biosynthetic pathway and its relationship to indolocarbazole biosynthesis.

César Sánchez;Alfredo F. Braña;Carmen Méndez;José A. Salas.
ChemBioChem (2006)

136 Citations

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