World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11327
World Ranking
13871
National Ranking
1088

Research.com Recognitions

  • 2018 - Interdisciplinary Prize, Royal Society of Chemistry (UK)

Overview

Barrie Wilkinson is a researcher affiliated with the John Innes Centre in the United Kingdom. Their body of work spans several interconnected fields, including biochemistry, genetics, molecular biology, medicine, and agricultural and biological sciences. The scientist's research integrates aspects of molecular biology, pharmacology, plant science, biotechnology, and organic chemistry.

The main topics covered by Wilkinson's research include microbial natural products and biosynthesis, genomics and phylogenetic studies, plant-microbe interactions and immunity, insect symbiosis and bacterial influences, legume nitrogen-fixing symbiosis, mycorrhizal fungi and plant interactions, and marine sponges and natural products.

Among recent publications, the following papers stand out:

  • StreptomycesEndophytes Promote Host Health and Enhance Growth across Plant Species, 2020, Applied and Environmental Microbiology
  • Antibiotics from rare actinomycetes, beyond the genus Streptomyces, 2023, Current Opinion in Microbiology
  • Chemical warfare between fungus-growing ants and their pathogens, 2020, Current Opinion in Chemical Biology
  • Competition-based screening helps to secure the evolutionary stability of a defensive microbiome, 2021, BMC Biology
  • Discovery of isoflavone phytoalexins in wheat reveals an alternative route to isoflavonoid biosynthesis, 2023, Nature Communications

Wilkinson frequently collaborates with several coauthors, among whom Matthew I. Hutchings appears most often, followed by Neil A. Holmes, Rebecca Devine, Sarah F. Worsley, and Sibyl F. D. Batey.

The most common publication venues for Wilkinson's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbiology
  • Nature Communications
  • Chemical Science
  • Microbial Genomics

In 2018, Wilkinson was awarded the Interdisciplinary Prize from the Royal Society of Chemistry in the United Kingdom, recognizing the interdisciplinary nature of their work.

Best Publications

  • Antibiotics: past, present and future

    Matthew I Hutchings;Andrew W Truman;Barrie Wilkinson

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Signal Sequence Recognition in Posttranslational Protein Transport across the Yeast ER Membrane

    Kathrin Plath;Walther Mothes;Barrie M Wilkinson;Colin J Stirling

  • Drug discovery beyond the 'rule-of-five'.

    Ming-Qiang Zhang;Barrie Wilkinson

  • Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

    Zohreh Hojati;Claire Milne;Barbara Harvey;Lyndsey Gordon

  • Engineering Broader Specificity into an Antibiotic-Producing Polyketide Synthase

    Andrew F. A. Marsden;Barrie Wilkinson;Jesús Cortés;Nicholas J. Dunster

  • Mining and engineering natural-product biosynthetic pathways

    Barrie Wilkinson;Jason Micklefield

  • Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055: Cluster Analysis and Assignment of Functions

    Carlos Olano;Barrie Wilkinson;César Sánchez;Steven J Moss

  • Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity

    Steven J. Moss;Christine J. Martin;Barrie Wilkinson

  • Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants

    Zhiwei Qin;John T. Munnoch;Rebecca Devine;Neil A. Holmes

  • Active-site residue, domain and module swaps in modular polyketide synthases

    Francesca Del Vecchio;Hrvoje Petkovic;Steven G. Kendrew;Lindsey Low

  • Mutasynthesis of Rapamycin Analogues through the Manipulation of a Gene Governing Starter Unit Biosynthesis

    Matthew A. Gregory;Hrvoje Petkovic;Rachel E. Lill;Steven J. Moss

  • Tritiated Chiral Alkanes as Substrates for Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath): Probes for the Mechanism of Hydroxylation

    Ann M. Valentine;Barrie Wilkinson;Katherine E. Liu;Sonja Komar-Panicucci

  • Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues

    Anand Ranganathan;Máire Timoney;Matthew Bycroft;Jesús Cortés

  • Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate

    Jennifer N. Andexer;Steven G. Kendrew;Mohammad Nur-e-Alam;Orestis Lazos

  • Roles of rapH and rapG in Positive Regulation of Rapamycin Biosynthesis in Streptomyces hygroscopicus

    Enej Kuščer;Nigel Coates;Iain Challis;Matt Gregory

  • Engineered Urdamycin Glycosyltransferases Are Broadened and Altered in Substrate Specificity

    Dirk Hoffmeister;Barrie Wilkinson;Graham Foster;Philip J Sidebottom

  • Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase

    Barrie Wilkinson;Graham Foster;Brian Am Rudd;Nicholas L Taylor

  • Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: insights into nitrile formation

    Carlos Olano;Steven J. Moss;Alfredo F. Braña;Rose M. Sheridan

  • Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis

    Russell J. Cox;Frank Glod;Deirdre Hurley;Colin M. Lazarus

Frequent Co-Authors

Peter F. Leadlay
Peter F. Leadlay University of Cambridge
Christine Martin
Christine Martin University of Clermont Auvergne
Douglas W. Yu
Douglas W. Yu University of East Anglia
Jason Micklefield
Jason Micklefield University of Manchester
James Staunton
James Staunton University of Cambridge
Alfredo F. Braña
Alfredo F. Braña University of Oviedo
Carmen Méndez
Carmen Méndez University of Oviedo
Philippe Gallay
Philippe Gallay Scripps Research Institute
Jacobus J. Boomsma
Jacobus J. Boomsma University of Copenhagen
José A. Salas
José A. Salas University of Oviedo

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