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Biology and Biochemistry

D-Index
72
Citations
18072
World Ranking
6317
National Ranking
445

Overview

Helge B. Bode is affiliated with Goethe University Frankfurt in Germany, focusing primarily on the interface of biochemistry, genetics, and molecular biology with applications in agricultural and biological sciences and medicine. Their research interest spans molecular biology, insect science, pharmacology, plant science, and genetics.

The scientist's main research topics include:

  • Entomopathogenic Microorganisms in Pest Control
  • Microbial Natural Products and Biosynthesis
  • Insect Symbiosis and Bacterial Influences
  • Chemical Synthesis and Analysis
  • Biochemical and Structural Characterization
  • Insect Resistance and Genetics
  • Nematode Management and Characterization Studies

Helge B. Bode has co-authored frequently with several researchers, including:

  • Yi-Ming Shi
  • Yan-Ni Shi
  • M. Groll
  • Edna Bode
  • Peter Grün

The scientist's work appears regularly in publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Nature Communications
  • Scientific Reports

Recent publications by Helge B. Bode include:

  • Towards the sustainable discovery and development of new antibiotics, 2021, Nature Reviews Chemistry
  • Roadmap for naming uncultivated Archaea and Bacteria, 2020, Nature Microbiology
  • Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides, 2023, Nature Communications
  • A community resource for paired genomic and metabolomic data mining, 2021, Nature Chemical Biology
  • Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria, 2022, Nature Chemistry

Best Publications

  • Big effects from small changes: Possible ways to explore nature's chemical diversity

    Helge Björn Bode;Barbara Bethe;Regina Höfs;Axel Zeeck

  • Towards the sustainable discovery and development of new antibiotics

    Marcus Miethke;Marco Pieroni;Tilmann Weber;Mark Brönstrup

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Complete genome sequence of the myxobacterium Sorangium cellulosum

    Susanne Schneiker;Olena Perlova;Olaf Kaiser;Klaus Gerth

  • Entomopathogenic bacteria as a source of secondary metabolites.

    Helge B Bode

  • The Impact of Bacterial Genomics on Natural Product Research

    Helge B. Bode;Rolf Müller

  • Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)‐oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca

    Helge Björn Bode;Bernd Zeggel;Barbara Silakowski;Silke C. Wenzel

  • The Entomopathogenic Bacterial Endosymbionts Xenorhabdus and Photorhabdus: Convergent Lifestyles from Divergent Genomes

    John M. Chaston;Garret Suen;Sarah L. Tucker;Aaron W. Andersen

  • BACTERIAL DEGRADATION OF NATURAL AND SYNTHETIC RUBBER

    Helge B. Bode;Kirsten Kerkhoff;Dieter Jendrossek

  • De novo design and engineering of non-ribosomal peptide synthetases

    Kenan A. J. Bozhüyük;Florian Fleischhacker;Annabell Linck;Frank Wesche

  • Bioactive natural products from novel microbial sources

    Victoria L. Challinor;Helge B. Bode

  • Pyrones as bacterial signaling molecules

    Alexander O Brachmann;Sophie Brameyer;Darko Kresovic;Ivana Hitkova

  • Cytosolic re-localization and optimization of valine synthesis and catabolism enables increased isobutanol production with the yeast Saccharomyces cerevisiae

    Dawid Brat;Christian Weber;Wolfram Lorenzen;Helge Björn Bode

  • Bacterial biosynthesis of a multipotent stilbene.

    Susan A. Joyce;Susan A. Joyce;Alexander O. Brachmann;Itamar Glazer;Lea Lango;Lea Lango

  • The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress

    Felix Sahm;Iris Oezen;Christiane A. Opitz;Bernhard Radlwimmer

  • A novel type of geosmin biosynthesis in myxobacteria.

    Jeroen S Dickschat;Helge B Bode;Taifo Mahmud;Rolf Müller

  • Natural product diversity associated with the nematode symbionts Photorhabdus and Xenorhabdus

    Nicholas J. Tobias;Hendrik Wolff;Bardya Djahanschiri;Florian Grundmann

  • Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains.

    Kenan A. J. Bozhüyük;Annabell Linck;Andreas Tietze;Janik Kranz

  • Aryl Polyenes, a Highly Abundant Class of Bacterial Natural Products, Are Functionally Related to Antioxidative Carotenoids.

    Tim A. Schöner;Sören Gassel;Ayako Osawa;Nicholas J. Tobias

  • Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus.

    Jeroen S. Dickschat;Silke C. Wenzel;Helge B. Bode;Rolf Müller

Frequent Co-Authors

Marcel Kaiser
Marcel Kaiser Swiss Tropical and Public Health Institute
Rolf Müller
Rolf Müller Saarland University
Axel Zeeck
Axel Zeeck University of Göttingen
Nicholas R. Waterfield
Nicholas R. Waterfield University of Warwick
Michael Groll
Michael Groll Technical University of Munich
Jeroen S. Dickschat
Jeroen S. Dickschat University of Bonn
Narisara Chantratita
Narisara Chantratita Mahidol University
Richard H. ffrench-Constant
Richard H. ffrench-Constant University of Exeter
Marco Thines
Marco Thines Goethe University Frankfurt
Reiner M. Kroppenstedt
Reiner M. Kroppenstedt Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures

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