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Biology and Biochemistry

D-Index
92
Citations
33727
World Ranking
2201
National Ranking
157

Overview

Peter Proksch is affiliated with Heinrich Heine University Düsseldorf in Germany and specializes in research within the fields of Biochemistry, Genetics, and Molecular Biology. Their scholarly work spans a range of subfields including Molecular Biology, Materials Chemistry, Plant Science, Toxicology, and Biotechnology.

Their main research topics encompass:

  • Bioactive Compounds and Antitumor Agents
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Cancer Therapeutics and Mechanisms
  • Bacterial Biofilms and Quorum Sensing
  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research

Peter Proksch has authored or co-authored several recent papers including:

  • Co-culture of the bacterium Pseudomonas aeruginosa with the fungus Fusarium tricinctum induces bacterial antifungal and quorum sensing signaling molecules, 2020, Phytochemistry Letters
  • Targeting the DNA damage response (DDR) by natural compounds, 2020, Bioorganic & Medicinal Chemistry
  • Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer, 2022, International Journal of Molecular Sciences
  • High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol, 2021, Cell Death and Disease
  • The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism, 2022, Cell Death and Disease

Frequent co-authors collaborating with Peter Proksch include:

  • Rainer Kalscheuer
  • Nicole Teusch
  • Björn Stork
  • Sebastian Wesselborg
  • Christoph Janiak

Their work is regularly published in journals and venues such as:

  • The Cambridge Structural Database
  • Cell Death and Disease
  • Phytochemistry Letters
  • Applied Microbiology and Biotechnology
  • Marine Drugs

This research portfolio shows a significant focus on molecular and chemical aspects of biology, particularly involving bioactive natural compounds and their effects on cancer cells, microbial interactions, and cellular mechanisms.

Best Publications

  • Drugs from the seas – current status and microbiological implications

    P Proksch;R A Edrada;R Ebel

  • Fungal endophytes from higher plants: a prolific source of phytochemicals and other bioactive natural products

    Amal H. Aly;Abdessamad Debbab;Julia Kjer;Peter Proksch

  • Fungal endophytes: unique plant inhabitants with great promises

    Amal Hassan Aly;Abdessamad Debbab;Peter Proksch

  • Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products

    Julia Kjer;Abdessamad Debbab;Amal H Aly;Peter Proksch

  • Bioactive compounds from marine bacteria and fungi.

    Abdessamad Debbab;Amal H. Aly;Wen H. Lin;Peter Proksch

  • Co-Cultivation—A Powerful Emerging Tool for Enhancing the Chemical Diversity of Microorganisms

    Andreas Marmann;Amal H. Aly;Wenhan Lin;Bingui Wang

  • Chaetopyranin, a benzaldehyde derivative, and other related metabolites from Chaetomium globosum, an endophytic fungus derived from the marine red alga Polysiphonia urceolata

    Song Wang;Xiao-Ming Li;Franka Teuscher;Dong-Li Li

  • Temporal variation of the microbial community associated with the mediterranean sponge Aplysina aerophoba

    Anja B. Friedrich;Isabell Fischer;Peter Proksch;Jörg Hacker

  • Low Concentrations of Flavonoids Are Protective in Rat H4IIE Cells Whereas High Concentrations Cause DNA Damage and Apoptosis

    Wim Wätjen;Gudrun Michels;Bärbel Steffan;Petra Niering

  • Cytotoxic metabolites from the fungal endophyte Alternaria sp. and their subsequent detection in its host plant Polygonum senegalense.

    Amal H. Aly;RuAngelie Edrada-Ebel;Ine Dewi Indriani;Victor Wray

  • Defensive roles for secondary metabolites from marine sponges and sponge-feeding nudibranchs

    Peter Proksch

  • Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin.

    Andreas Kampkötter;Claudia Timpel;Ruben Felix Zurawski;Sven Ruhl

  • New communesin derivatives from the fungus Penicillium sp. derived from the Mediterranean sponge Axinella verrucosa

    Raquel Jadulco;Ru Angelie Edrada;Rainer Ebel;Albrecht Berg

  • Inducing Secondary Metabolite Production by the Endophytic Fungus Fusarium tricinctum through Coculture with Bacillus subtilis

    Antonius R. B. Ola;Dhana Thomy;Daowan Lai;Heike Brötz-Oesterhelt

  • New pathway to polyketides in plants

    Stefan Eckermann;Gudrun Schröder;Jürgen Schmidt;Dieter Strack

  • Microbial diversity in the marine sponge Aplysina cavernicola (formerly Verongia cavernicola) analyzed by fluorescence in situ hybridization (FISH)

    A. B. Friedrich;H. Merkert;T. Fendert;J. Hacker

  • Bioactive metabolites from the endophytic fungus Ampelomyces sp. isolated from the medicinal plant Urospermum picroides

    Amal H. Aly;RuAngelie Edrada-Ebel;Victor Wray;Werner E.G. Müller

  • New Natural Products from the Sponge-Derived Fungus Aspergillus niger

    J Hiort;K Maksimenka;M Reichert;S Perović-Ottstadt

  • Chromenes and benzofurans of the asteraceae, their chemistry and biological significance

    Peter Proksch;Eloy Rodriguez

  • Methods for isolation, purification and structural elucidation of bioactive secondary metabolites from marine invertebrates

    Sherif S Ebada;Ru Angelie Edrada;Wenhan Lin;Peter Proksch

Frequent Co-Authors

Wenhan Lin
Wenhan Lin Peking University
Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Werner E. G. Müller
Werner E. G. Müller Johannes Gutenberg University of Mainz
Rainer Ebel
Rainer Ebel University of Aberdeen
Tibor Kurtán
Tibor Kurtán University of Debrecen
RuAngelie Edrada-Ebel
RuAngelie Edrada-Ebel University of Strathclyde
Ludger Witte
Ludger Witte Technische Universität Braunschweig
Matthias U. Kassack
Matthias U. Kassack Heinrich Heine University Düsseldorf
Bin-Gui Wang
Bin-Gui Wang Chinese Academy of Sciences
Christoph Janiak
Christoph Janiak Heinrich Heine University Düsseldorf

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