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Alejandro F. De Nicola

Alejandro F. De Nicola

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Neuroscience
Argentina
2026

D-Index & Metrics

Neuroscience

D-Index
65
Citations
12562
World Ranking
3171
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Argentina Leader Award
  • 2025 - Research.com Neuroscience in Argentina Leader Award
  • 1979 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Alejandro F. De Nicola is affiliated with the University of Buenos Aires in Argentina. Their research focuses extensively on topics within medicine and neuroscience, with a significant emphasis on neurology, pathology and forensic medicine, behavioral neuroscience, endocrinology, diabetes and metabolism, and genetics.

Their main research topics include:

  • Amyotrophic Lateral Sclerosis Research
  • Stress Responses and Cortisol
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenetic and Muscular Disorders Research
  • Neurogenesis and Neuroplasticity Mechanisms
  • Hormonal Regulation and Hypertension
  • Multiple Sclerosis Research Studies

De Nicola has contributed to several recent scientific papers, including:

  • Insights into the Therapeutic Potential of Glucocorticoid Receptor Modulators for Neurodegenerative Diseases, 2020, International Journal of Molecular Sciences
  • Progesterone and Allopregnanolone Neuroprotective Effects in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis, 2021, Cellular and Molecular Neurobiology

Other relevant papers from their field, although authored by colleagues, are:

  • Progress in progestin-based therapies for neurological disorders, 2020, Neuroscience & Biobehavioral Reviews
  • Spinal Cord Injury Leads to Hippocampal Glial Alterations and Neural Stem Cell Inactivation, 2020, Cellular and Molecular Neurobiology
  • IGF1 Gene Therapy Reversed Cognitive Deficits and Restored Hippocampal Alterations After Chronic Spinal Cord Injury, 2021, Molecular Neurobiology

Frequent co-authors who collaborate with De Nicola include:

  • María Meyer
  • Marı́a Claudia González Deniselle
  • Analı́a Lima
  • Paulina Roig
  • Michaël Schumacher

De Nicola's publications appear most often in the following scientific journals and venues:

  • Molecular Neurobiology
  • Cellular and Molecular Neurobiology
  • Journal of Neuroendocrinology
  • The Journal of Steroid Biochemistry and Molecular Biology
  • International Journal of Molecular Sciences

Over their career, De Nicola has produced work largely situated in medicine, with 31 publications in this field, and neuroscience, with 19 publications.

In 1979, Alejandro F. De Nicola was awarded the title of Fellow of the John Simon Guggenheim Memorial Foundation.

Best Publications

  • Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors

    M. Schumacher;C. Mattern;A. Ghoumari;J.P. Oudinet

  • Progesterone: therapeutic opportunities for neuroprotection and myelin repair.

    Michael Schumacher;Rachida Guennoun;Donald G. Stein;Alejandro Federico de Nicola

  • Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination

    Michael Schumacher;Rachida Guennoun;Françoise Robert;Claude Carelli

  • Steroid synthesis and metabolism in the nervous system: Trophic and protective effects

    Schumacher M;Akwa Y;Guennoun R;Robert F

  • Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection.

    R. Guennoun;F. Labombarda;M.C. Gonzalez Deniselle;P. Liere

  • Importance of the brain corticosteroid receptor balance in metaplasticity, cognitive performance and neuro-inflammation.

    E.R. de Kloet;O.C. Meijer;A.F. de Nicola;R.H. de Rijk

  • Regulation of glucocorticoid receptors in brain by corticosterone treatment of adrenalectomized rats.

    S. Tornello;E. Orti;A.F. de Nicola;T.C. Rainbow

  • Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration.

    Alejandro F. De Nicola;Alejandro F. De Nicola;Florencia Labombarda;Florencia Labombarda;Maria Claudia Gonzalez Deniselle;Maria Claudia Gonzalez Deniselle;Susana L. Gonzalez;Susana L. Gonzalez

  • Aldosterone effects on salt appetite in adrenalectomized rats.

    B. S. Mcewen;L. T. Lambdin;T. C. Rainbow;A. F. De Nicola

  • Effects of progesterone in the spinal cord of a mouse model of multiple sclerosis.

    Laura Ines Garay;Maria Claudia Gonzalez Deniselle;Maria Claudia Gonzalez Deniselle;Analia Ethel Lima;Paulina Roig

  • Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes

    Edgardo O. Alvarez;Juan Beauquis;Yanina Revsin;Arturo M. Banzan

  • Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease.

    María Claudia Gonzalez Deniselle;Juan José López-Costa;Jorge Pecci Saavedra;Luciana Pietranera

  • Further studies of brain aldosterone binding sites employing new mineralocorticoid and glucocorticoid receptor markers in vitro.

    Hector Coirini;Ana Mari´a Magarin˜os;Alejandro F. De Nicola;Thomas C. Rainbow

  • Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin-induced diabetic mice: reversion by antidepressant treatment

    Juan Beauquis;Paulina Roig;Françoise Homo-Delarche;Alejandro De Nicola;Alejandro De Nicola

  • Glucocorticoid Receptor Blockade Normalizes Hippocampal Alterations and Cognitive Impairment in Streptozotocin-Induced Type 1 Diabetes Mice

    Yanina Revsin;Niels V. Rekers;Mieke C. Louwe;Flavia Eugenia Saravia

  • The placenta as a glucocorticoid target tissue: exchange assay of (3H)-dexamethasone binding and effect of steroids on receptor content.

    C Heller;H Coirini;A F De Nicola

  • Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice

    Flavia E Saravia;Flavia E Saravia;Yanina Revsin;Maria Claudia Gonzalez Deniselle;Maria Claudia Gonzalez Deniselle;Susana L Gonzalez;Susana L Gonzalez

  • Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord.

    S.L González;F Labombarda;F Labombarda;M.C González Deniselle;M.C González Deniselle;R Guennoun

  • Neuroprotective actions of estradiol revisited

    Iñigo Azcoitia;Maria-Angeles Arevalo;Alejandro F. De Nicola;Luis M. Garcia-Segura

  • Effects of injury and progesterone treatment on progesterone receptor and progesterone binding protein 25-Dx expression in the rat spinal cord.

    F. Labombarda;S. L. Gonzalez;M. C. Gonzalez Deniselle;G. P. Vinson

Frequent Co-Authors

Florencia Labombarda
Florencia Labombarda University of Buenos Aires
Claudia A. Grillo
Claudia A. Grillo University of South Carolina
Bruce S. McEwen
Bruce S. McEwen Rockefeller University
Marcelo J. Villar
Marcelo J. Villar Austral University
Luis M. Garcia-Segura
Luis M. Garcia-Segura Spanish National Research Council
Thomas C. Rainbow
Thomas C. Rainbow University of Pennsylvania
Joseph Weidenfeld
Joseph Weidenfeld Hebrew University of Jerusalem
Donald W. Pfaff
Donald W. Pfaff Rockefeller University
Gareth Leng
Gareth Leng University of Edinburgh
Jean-Didier Vincent
Jean-Didier Vincent Centre national de la recherche scientifique, CNRS

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