World's Best Scientists 2026 revealed!
Roberta Diaz Brinton

Roberta Diaz Brinton

D-Index & Metrics

Neuroscience

D-Index
92
Citations
28621
World Ranking
1033
National Ranking
546

Medicine

D-Index
92
Citations
28620
World Ranking
11389
National Ranking
5838

Overview

Roberta Diaz Brinton is affiliated with the University of Arizona in the United States. Their scholarly work primarily spans the field of medicine, with a total of 201 publications. The research focus is deeply rooted in physiology, molecular biology, neurology, endocrinology, diabetes and metabolism, and genetics.

The scientist has contributed extensively to several main topics, including:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and neurodegeneration mechanisms
  • Dementia and cognitive impairment research
  • Estrogen and related hormone effects
  • Menopause: health impacts and treatments
  • Tryptophan and brain disorders
  • Stress responses and cortisol

Roberta Diaz Brinton's recent papers cover a range of topics related to brain health, neurodegenerative diseases, and metabolic processes. Notable publications include:

  • "Sex and gender: modifiers of health, disease, and medicine" (2020), published in The Lancet
  • "Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing" (2020), published in Nature Reviews Drug Discovery
  • "ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism" (2021), published in Cell Reports
  • "Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration" (2023), published in Nature Metabolism
  • "Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition" (2021), published in Scientific Reports

Frequent collaborators in their research include Francesca Vitali, Lisa Mosconi, Adam C. Raikes, Gregory L. Branigan, and Silky Pahlajani.

The scholar has frequently published in several academic journals, which include:

  • Alzheimer s & Dementia
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Neurology
  • Scientific Reports
  • Alzheimer s & Dementia Translational Research & Clinical Interventions

In addition to journal articles, Roberta Diaz Brinton has produced book publications, such as the work published by RAND Corporation eBooks titled "Research Funding for Women's Health: A Modeling Study of Societal Impact: Findings for Lung Cancer" (2022).

Best Publications

  • Sex and gender: modifiers of health, disease, and medicine.

    Franck Mauvais-Jarvis;Noel Bairey Merz;Peter J. Barnes;Roberta D. Brinton

  • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

    Jia Yao;Ronald W. Irwin;Liqin Zhao;Jon Nilsen

  • Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

    Stephen C. Cunnane;Eugenia Trushina;Cecilie Morland;Alessandro Prigione

  • Progesterone Receptors: Form and Function in Brain

    Roberta Diaz Brinton;Richard F. Thompson;Michael R. Foy;Michel Baudry

  • Age, APOE and sex: Triad of risk of Alzheimer's disease.

    Brandalyn C. Riedel;Paul M. Thompson;Roberta Diaz Brinton

  • 17beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation.

    M. R. Foy;J. Xu;X. Xie;R. D. Brinton

  • Perimenopause as a neurological transition state

    Roberta D. Brinton;Jia Yao;Fei Yin;Wendy J. Mack

  • Estrogen: a master regulator of bioenergetic systems in the brain and body.

    Jamaica R Rettberg;Jia Yao;Roberta Diaz Brinton

  • Estrogen, Menopause, and the Aging Brain: How Basic Neuroscience Can Inform Hormone Therapy in Women

    John H Morrison;Roberta D Brinton;Peter J Schmidt;Andrea C Gore

  • Impact of progestins on estrogen-induced neuroprotection: Synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate

    Jon Nilsen;Roberta Diaz Brinton

  • The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications.

    Roberta Diaz Brinton

  • Mechanism of estrogen-mediated neuroprotection: regulation of mitochondrial calcium and Bcl-2 expression.

    Jon Nilsen;Roberta Diaz Brinton

  • ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism

    Guoyuan Qi;Yashi Mi;Xiaojian Shi;Haiwei Gu

  • 17β-estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuroprotection

    T.-W. Wu;J.M. Wang;S. Chen;R.D. Brinton

  • Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

    Ronald W. Irwin;Jia Yao;Ryan T. Hamilton;Enrique Cadenas

  • Female Sex and Alzheimer’s Risk: The Menopause Connection

    Unknown

  • Estrogen-induced plasticity from cells to circuits: predictions for cognitive function

    Roberta Diaz Brinton

  • Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

    Jun Ming Wang;Chanpreet Singh;Lifei Liu;Ronald W. Irwin

  • The Neurosteroid Allopregnanolone Promotes Proliferation of Rodent and Human Neural Progenitor Cells and Regulates Cell-Cycle Gene and Protein Expression

    Jun Ming Wang;Patrick B. Johnston;Bret Gene Ball;Roberta Diaz Brinton

  • Minireview: Translational Animal Models of Human Menopause: Challenges and Emerging Opportunities

    Roberta Diaz Brinton

  • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling

    Jon Nilsen;Roberta Diaz Brinton

  • Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons

    Liqin Zhao;Tzu-wei Wu;Roberta Diaz Brinton

  • Estrogen receptor α and β differentially regulate intracellular Ca2+ dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons

    Liqin Zhao;Roberta Diaz Brinton

Frequent Co-Authors

Enrique Cadenas
Enrique Cadenas University of Southern California
Lon S. Schneider
Lon S. Schneider University of Southern California
Wendy J. Mack
Wendy J. Mack University of Southern California
Victor W. Henderson
Victor W. Henderson Stanford University
Richard F. Thompson
Richard F. Thompson University of Southern California
Howard N. Hodis
Howard N. Hodis University of Southern California
Mark A. Espeland
Mark A. Espeland Wake Forest University
Mony J. de Leon
Mony J. de Leon Cornell University
Michael A. Rogawski
Michael A. Rogawski University of California, Davis
Carol A. Barnes
Carol A. Barnes University of Arizona

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in Neuroscience, there are several related online degrees and career opportunities to consider. Many students in this field explore psychology, counseling, or social work to complement their neuroscience expertise.

Online psychology and therapy degree programs have become increasingly accessible and affordable. If you’d like to work directly with individuals or families, pursuing a marriage and family therapist degree is a practical option. Alternatively, you can deepen your understanding of psychology’s diverse applications with an affordable online master's in psychology.

There are also a variety of most affordable online psychology degree programs to help reduce student debt while you build a solid foundation in behavioral science. Those interested in social work and advocacy can look into the easiest msw online program options, some of which welcome students from neuroscience or psychology backgrounds.

Exploring these pathways offers versatile career choices, from research and mental health services to clinical practice. Online study options make it convenient to further your education and pursue your professional goals in the expanding field of brain and behavioral sciences.

Best Scientists Citing Roberta Diaz Brinton

Trending Scientists