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James W. Simpkins

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Neuroscience 96 880 789 472 414 460 29570
Medicine 96 9775 9171 5025 4643 471 29766

James W. Simpkins publications per year

The chart shows the history of publications by James W. Simpkins between 1976 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. James W. Simpkins published across 50 years, from 1976 to 2025, averaging 9.8 papers a year. Output peaked at 30 publications in 2005. 7 of the 490 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1976 to 2025. Vertical axis: number of publications, 0 to 30. Peak 30 publications in 2005. 1976: 4 publications 1977: 4 publications 1978: 3 publications 1979: 4 publications 1980: 7 publications 1981: 5 publications 1982: 5 publications 1983: 12 publications 1984: 12 publications 1985: 9 publications 1986: 11 publications 1987: 13 publications 1988: 9 publications 1989: 12 publications 1990: 14 publications 1991: 13 publications 1992: 9 publications 1993: 3 publications 1994: 9 publications 1995: 5 publications 1996: 4 publications 1997: 12 publications 1998: 13 publications 1999: 5 publications 2000: 10 publications 2001: 9 publications 2002: 8 publications 2003: 16 publications 2004: 15 publications 2005: 30 publications 2006: 8 publications 2007: 12 publications 2008: 18 publications 2009: 16 publications 2010: 13 publications 2011: 16 publications 2012: 15 publications 2013: 9 publications 2014: 16 publications 2015: 17 publications 2016: 16 publications 2017: 9 publications 2018: 7 publications 2019: 9 publications 2020: 5 publications 2021: 7 publications 2022: 4 publications 2023: 1 publication 2024: 4 publications 2025: 3 publications
1976 2025

490 publications in total across all disciplines

View publications per year as a table
James W. Simpkins: publications per year, 1976 to 2025
Year Publications
1976 4
1977 4
1978 3
1979 4
1980 7
1981 5
1982 5
1983 12
1984 12
1985 9
1986 11
1987 13
1988 9
1989 12
1990 14
1991 13
1992 9
1993 3
1994 9
1995 5
1996 4
1997 12
1998 13
1999 5
2000 10
2001 9
2002 8
2003 16
2004 15
2005 30
2006 8
2007 12
2008 18
2009 16
2010 13
2011 16
2012 15
2013 9
2014 16
2015 17
2016 16
2017 9
2018 7
2019 9
2020 5
2021 7
2022 4
2023 1
2024 4
2025 3
Total 490
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James W. Simpkins publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where James W. Simpkins sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 86 bars. Horizontal axis: publications, 38–47 to 887+. Vertical axis: number of scientists, 0 to 539. Most scientists, 539, have 98–107 publications. The last bar groups every scientist with 887 publications or more. The highlighted bar, 458–467 publications, is where this scientist sits. 38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientist 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38–47 publications 887+

This scientist: 460 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

View publications distribution as a table
Number of Neuroscience scientists by publication count, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
Publications Scientists This scientist
38–47 18
48–57 79
58–67 193
68–77 323
78–87 406
88–97 452
98–107 539
108–117 505
118–127 522
128–137 469
138–147 456
148–157 459
158–167 397
168–177 383
178–187 350
188–197 302
198–207 306
208–217 262
218–227 242
228–237 220
238–247 203
248–257 174
258–267 176
268–277 175
278–287 125
288–297 116
298–307 127
308–317 128
318–327 99
328–337 89
338–347 78
348–357 96
358–367 66
368–377 59
378–387 65
388–397 54
398–407 48
408–417 49
418–427 34
428–437 31
438–447 30
448–457 31
458–467 36 460
468–477 40
478–487 35
488–497 30
498–507 23
508–517 26
518–527 20
528–537 23
538–547 20
548–557 20
558–567 17
568–577 14
578–587 20
588–597 20
598–607 19
608–617 18
618–627 17
628–637 11
638–647 11
648–657 11
658–667 8
668–677 7
678–687 11
688–697 10
698–707 4
708–717 6
718–727 5
728–737 5
738–747 9
748–757 9
758–767 3
768–777 7
778–787 7
788–797 6
798–807 2
808–817 2
818–827 7
828–837 0
838–847 9
848–857 3
858–867 1
868–877 3
878–886 6
887+ 100
Download as CSV

James W. Simpkins D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where James W. Simpkins sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 68 bars. Horizontal axis: D-Index, 30–31 to 163+. Vertical axis: number of scientists, 0 to 512. Most scientists, 512, have 46–47 D-Index. The last bar groups every scientist with 163 D-Index or more. The highlighted bar, 96–97 D-Index, is where this scientist sits. 30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30–31 D-Index 163+

This scientist: 96 D-Index — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

View D-Index distribution as a table
Number of Neuroscience scientists by D-index, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
D-Index Scientists This scientist
30–31 42
32–33 172
34–35 296
36–37 435
38–39 459
40–41 456
42–43 467
44–45 478
46–47 512
48–49 435
50–51 425
52–53 418
54–55 392
56–57 357
58–59 334
60–61 328
62–63 260
64–65 278
66–67 239
68–69 250
70–71 210
72–73 200
74–75 189
76–77 170
78–79 146
80–81 113
82–83 126
84–85 100
86–87 84
88–89 99
90–91 84
92–93 85
94–95 72
96–97 76 96
98–99 45
100–101 49
102–103 43
104–105 32
106–107 45
108–109 50
110–111 32
112–113 39
114–115 32
116–117 29
118–119 27
120–121 19
122–123 23
124–125 27
126–127 16
128–129 24
130–131 13
132–133 21
134–135 17
136–137 14
138–139 15
140–141 10
142–143 10
144–145 13
146–147 9
148–149 8
150–151 6
152–153 6
154–155 7
156–157 7
158–159 10
160–161 4
162 8
163+ 100
Download as CSV

Overview

James W. Simpkins is affiliated with West Virginia University in the United States. Their research contributions span multiple disciplines, primarily within biochemistry, genetics, molecular biology, neuroscience, and medicine. Subfields of focus include molecular biology, neurology, physiology, cancer research, and genetics.

Their work engages with several key topics, notably:

  • Extracellular vesicles in disease
  • Alzheimer's disease research and treatments
  • Neuroinflammation and neurodegeneration mechanisms
  • Barrier structure and function studies
  • Neurological disease mechanisms and treatments
  • MicroRNA in disease regulation
  • RNA interference and gene delivery

Simpkins has published extensively in journals such as Biosensors and Bioelectronics, Nature Communications, Journal of Alzheimer's Disease, Alzheimer's & Dementia, and Metabolic Brain Disease.

Recent papers authored or co-authored by Simpkins include:

  • "Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke" (2020) published in Metabolic Brain Disease
  • "A 'hot Spot'-Enhanced paper lateral flow assay for ultrasensitive detection of traumatic brain injury biomarker S-100β in blood plasma" (2021) published in Biosensors and Bioelectronics
  • "Blood substitution therapy rescues the brain of mice from ischemic damage" (2020) published in Nature Communications
  • "Amyloid-β Causes Mitochondrial Dysfunction via a Ca2+-Driven Upregulation of Oxidative Phosphorylation and Superoxide Production in Cerebrovascular Endothelial Cells" (2020) published in Journal of Alzheimer's Disease
  • "miR-146a Dysregulates Energy Metabolism During Neuroinflammation" (2021) published in Journal of Neuroimmune Pharmacology

Among frequent collaborators, Simpkins has worked with Saumyendra N. Sarkar, Xuefang Ren, Elizabeth B. Engler-Chiurazzi, Heng Hu, and Dominic D. Quintana multiple times, reflecting ongoing partnerships in research projects.

Best Publications

  • Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats.

    Meharvan Singh;Edwin M. Meyer;William J. Millard;James W. Simpkins

  • Neuroprotective effects of estrogens: potential mechanisms of action.

    Pattie S. Green;James W. Simpkins

  • Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat.

    James W. Simpkins;Gopal Rajakumar;Yu Qi Zhang;Christopher E. Simpkins

  • The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats.

    Meharvan Singh;E. M. Meyer;J. W. Simpkins

  • Mitochondrial localization of estrogen receptor β

    Shao Hua Yang;Ran Liu;Evelyn J. Perez;Yi Wen

  • Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

    David E. Harrison;Randy Strong;David B. Allison;Bruce N. Ames

  • Depletion of GGA3 Stabilizes BACE and Enhances β-Secretase Activity

    Giuseppina Tesco;Young Ho Koh;Eugene L. Kang;Andrew N. Cameron

  • Role of Estrogen Replacement Therapy in Memory Enhancement and the Prevention of Neuronal Loss Associated With Alzheimer’s Disease

    James W Simpkins;Pattie S Green;Kelly E Gridley;Meharvan Singh

  • Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

    Randy Strong;Richard A Miller;Adam Antebi;Clinton M Astle

  • Evidence for Depressed Catecholamine and Enhanced Serotonin Metabolism in Aging Male Rats: Possible Relation to Gondotropin Secretion2

    J. W. Simpkins;G. P. Mueller;H. H. Huang;J. Meites

  • 17α-Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells

    Pattie S. Green;Jean Bishop;James W. Simpkins

  • Effects of gender and estradiol treatment on focal brain ischemia

    Yu Qi Zhang;Jiong Shi;Gopal Rajakumar;Arthur L. Day

  • Protective effect of estrogens against oxidative damage to heart and skeletal muscle in vivo and in vitro.

    Adam M. Persky;Pattie S. Green;Leighann Stubley;Cynthia O. Howell

  • Estradiol protects against β-amyloid (25–35)-induced toxicity in SK-N-SH human neuroblastoma cells

    Pattie S. Green;Kelly E. Gridley;James W. Simpkins

  • Estradiol protects against ATP depletion, mitochondrial membrane potential decline and the generation of reactive oxygen species induced by 3-nitroproprionic acid in SK-N-SH human neuroblastoma cells

    J. Wang;P. S. Green;J. W. Simpkins

  • Estradiol Exerts Neuroprotective Effects When Administered After Ischemic Insult

    Shao Hua Yang;Jiong Shi;Arthur L Day;James W. Simpkins

  • Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection

    Yi Wen;Wenjun Li;Ethan C. Poteet;Luokun Xie

  • Increased β-secretase activity and expression in rats following transient cerebral ischemia

    Yi Wen;Otuonye Onyewuchi;Shaohua Yang;Ran Liu

  • The Critical Need to Promote Research of Aging and Aging-related Diseases to Improve Health and Longevity of the Elderly Population

    Kunlin Jin;James W. Simpkins;Xunming Ji;Miriam Leis

  • Testosterone increases and estradiol decreases middle cerebral artery occlusion lesion size in male rats

    Toni Hawk;Y. Q. Zhang;Gopal Rajakumar;Arthur L. Day

  • Phenolic A ring requirement for the neuroprotective effects of steroids

    Pattie S. Green;Katherine Gordon;James W. Simpkins

Frequent Co-Authors

Nicholas Bodor
Nicholas Bodor University of Florida
Satya P. Kalra
Satya P. Kalra University of Florida
Douglas F. Covey
Douglas F. Covey Washington University in St. Louis
Pushpa S. Kalra
Pushpa S. Kalra University of Florida
Marcus E. Brewster
Marcus E. Brewster Johnson & Johnson (United States)
Joseph Meites
Joseph Meites Michigan State University
Ahamed H. Idris
Ahamed H. Idris The University of Texas Southwestern Medical Center
Liang-Jun Yan
Liang-Jun Yan University of North Texas Health Science Center
Edwin M. Meyer
Edwin M. Meyer University of Florida
Robert J. Handa
Robert J. Handa Colorado State University

External Links

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Best Scientists Citing James W. Simpkins

Luis M. Garcia-Segura

Luis M. Garcia-Segura

Spanish National Research Council

Publications: 102

Phyllis M. Wise

Phyllis M. Wise

University of Washington

Publications: 66

Roberta Diaz Brinton

Roberta Diaz Brinton

University of Arizona

Publications: 61

Nicholas Bodor

Nicholas Bodor

University of Florida

Publications: 57

Farida Sohrabji

Farida Sohrabji

Texas A&M University

Publications: 41

Satya P. Kalra

Satya P. Kalra

University of Florida

Publications: 39

Bruce S. McEwen

Bruce S. McEwen

Rockefeller University

Publications: 39

Richard A. Miller

Richard A. Miller

University of Michigan–Ann Arbor

Publications: 38

Christian J. Pike

Christian J. Pike

University of Southern California

Publications: 38

George E. Barreto

George E. Barreto

University of Limerick

Publications: 35

Darrell W. Brann

Darrell W. Brann

Augusta University

Publications: 35

Caleb E. Finch

Caleb E. Finch

University of Southern California

Publications: 31

Philip W. Landfield

Philip W. Landfield

University of Kentucky

Publications: 30

William R. Crowley

William R. Crowley

University of Utah

Publications: 29

George Perry

George Perry

The University of Texas at San Antonio

Publications: 29

Louise D. McCullough

Louise D. McCullough

The University of Texas Health Science Center at Houston

Publications: 28

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