World's Best Scientists 2026 revealed!

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Medicine

D-Index
72
Citations
19333
World Ranking
19828
National Ranking
9877

Overview

Robert J. Handa was affiliated with Colorado State University in the United States. Their research primarily focused on neuroscience and medicine, with significant contributions to subfields such as behavioral neuroscience, social psychology, molecular biology, endocrine and autonomic systems, and pediatrics, perinatology, and child health.

Their work addressed various topics including stress responses and cortisol, neuroendocrine regulation and behavior, circadian rhythm and melatonin, birth, development, and health, tryptophan and brain disorders, receptor mechanisms and signaling, and genetic associations and epidemiology.

Frequent venues for publication included Endocrinology Diabetes & Metabolism and the Journal of the Endocrine Society, each hosting multiple publications by Handa. Other noteworthy publication venues were Biological Psychiatry, Biology of Sex Differences, and BMC Neuroscience.

Notable recent papers featured in their body of work included:

  • "Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders," 2021, Biological Psychiatry
  • "Roles for androgens in mediating the sex differences of neuroendocrine and behavioral stress responses," 2020, Biology of Sex Differences
  • "Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive-like behaviors and deficits in startle responses," 2021, BMC Neuroscience
  • "Social isolation alters hypothalamic pituitary adrenal axis activity after chronic variable stress in male C57BL/6 mice," 2020, Stress
  • "Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders," 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in Handa's research included Julietta A. Sheng, Stuart Tobet, Ashley Heck, Ashley L. Russell, and T. John Wu. These partnerships contributed to multiple publications and research projects within their fields of study.

Best Publications

  • Gonadal Steroid Hormone Receptors and Sex Differences in the Hypothalamo-Pituitary-Adrenal Axis

    Robert J. Handa;Loyd H. Burgess;Janice E. Kerr;Joan A. O'Keefe

  • Chronic estrogen-induced alterations in adrenocorticotropin and corticosterone secretion, and glucocorticoid receptor-mediated functions in female rats.

    Loyd H. Burgess;Robert J. Handa

  • S-Equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora

    Kenneth D R Setchell;Carlo Clerici;Edwin D Lephart;Sidney J Cole

  • Non-genomic Actions of Androgens

    C. D. Foradori;M. J. Weiser;R. J. Handa

  • Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

    Mario G. Oyola;Robert J. Handa

  • Novel Actions of Estrogen Receptor-β on Anxiety-Related Behaviors

    Trent D. Lund;Tomislav Rovis;Wilson C. J. Chung;Robert J. Handa

  • Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors

    Robert J Handa;Karin M Nunley;Karin M Nunley;Stanley A Lorens;Stanley A Lorens;Jeffrey P Louie;Jeffrey P Louie

  • Gonadal steroid hormones and the hypothalamo–pituitary–adrenal axis

    Robert J. Handa;Michael J. Weiser

  • Distribution and hormonal regulation of androgen receptor (AR) and AR messenger ribonucleic acid in the rat hippocampus.

    Janice E. Kerr;Robert J. Allore;Sheryl G. Beck;Robert J. Handa

  • Estrogen Regulates the Development of Brain-Derived Neurotrophic Factor mRNA and Protein in the Rat Hippocampus

    Derek T. Solum;Robert J. Handa

  • Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones

    Ashley L. Heck;Robert J. Handa

  • Equol Is a Novel Anti-Androgen that Inhibits Prostate Growth and Hormone Feedback

    Trent D. Lund;Daniel J. Munson;Megan E. Haldy;Kenneth D.R. Setchell

  • The Androgen 5α-Dihydrotestosterone and Its Metabolite 5α-Androstan-3β, 17β-Diol Inhibit the Hypothalamo–Pituitary–Adrenal Response to Stress by Acting through Estrogen Receptor β-Expressing Neurons in the Hypothalamus

    Trent D. Lund;Laura R. Hinds;Robert J. Handa

  • Estrogen receptor beta in the brain: From form to function

    Michael J. Weiser;Chad D. Foradori;Robert J. Handa

  • ESTROGEN IMPAIRS GLUCOCORTICOID DEPENDENT NEGATIVE FEEDBACK ON THE HYPOTHALAMIC–PITUITARY–ADRENAL AXIS VIA ESTROGEN RECEPTOR ALPHA WITHIN THE HYPOTHALAMUS

    M.J. Weiser;R.J. Handa

  • An alternate pathway for androgen regulation of brain function: Activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5α-androstane 3β, 17β diol

    Robert J. Handa;Toni R. Pak;Toni R. Pak;Andrea E. Kudwa;Trent D. Lund

  • Estrogen receptor beta regulates the expression of tryptophan-hydroxylase 2 mRNA within serotonergic neurons of the rat dorsal raphe nuclei.

    Nina C Donner;Robert J Handa;Robert J Handa

  • Androgen inhibits, while oestrogen enhances, restraint-induced activation of neuropeptide neurones in the paraventricular nucleus of the hypothalamus.

    Trent D. Lund;D. J. Munson;M. E. Haldy;R. J. Handa

  • Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy.

    Elena W. Bingaman;Debra J. Magnuson;Thackery S. Gray;Robert J. Handa

  • The Hypothalamic-Pituitary-Adrenal Axis: Development, Programming Actions of Hormones, and Maternal-Fetal Interactions.

    Julietta A. Sheng;Natalie J. Bales;Sage A. Myers;Anna I. Bautista

Frequent Co-Authors

Jill M. Goldstein
Jill M. Goldstein Harvard University
Stuart A. Tobet
Stuart A. Tobet Colorado State University
James W. Simpkins
James W. Simpkins West Virginia University
Melvin E. Andersen
Melvin E. Andersen Research Triangle Park Foundation
Noel S. Weiss
Noel S. Weiss University of Washington
Victor D. Ramirez
Victor D. Ramirez University of Illinois at Urbana-Champaign
Susan E. Fahrbach
Susan E. Fahrbach Wake Forest University
Joan I. Morrell
Joan I. Morrell Rutgers, The State University of New Jersey
Alan G. Watts
Alan G. Watts University of Southern California
John E. McGeary
John E. McGeary Brown University

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