World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
103
Citations
36306
World Ranking
1321
National Ranking
773

Medicine

D-Index
103
Citations
37596
World Ranking
7393
National Ranking
3865

Overview

Melvin E. Andersen is affiliated with the Research Triangle Park Foundation in the United States. Their research primarily spans several scientific fields, including Environmental Science, Medicine, and Biochemistry, Genetics and Molecular Biology.

Their work covers several specialized subfields such as Health, Toxicology and Mutagenesis, Cancer Research, Molecular Biology, Environmental Chemistry, and Pharmacology. The core topics of their research involve Carcinogens and Genotoxicity Assessment, effects and risks related to endocrine disrupting chemicals, the impact of toxic organic pollutants, per- and polyfluoroalkyl substances research, alternatives to animal testing, air quality and health impacts, and pharmacogenetics and drug metabolism.

Andersen has contributed to a number of recent research publications. These include:

  • Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms (2021, Toxicology)
  • Using quantitative modeling tools to assess pharmacokinetic bias in epidemiological studies showing associations between biomarkers and health outcomes at low exposures (2021, Environmental Research)

Frequent collaborators in Andersen's research include Harvey J. Clewell, Weidong Qu, Michael B. Black, Jerry L. Campbell, and Patrick D. McMullen, reflecting ongoing partnerships within the field.

Andersen's publications commonly appear in journals such as Toxicological Sciences, Toxicology and Applied Pharmacology, Toxicology, Regulatory Toxicology and Pharmacology, and bioRxiv (Cold Spring Harbor Laboratory). These venues are notable for toxicological and environmental health research, aligning closely with Andersen's areas of expertise.

Best Publications

  • TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY

    Daniel Krewski;Daniel Acosta;Melvin Andersen;Henry Anderson

  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

    Patricio Godoy;Nicola J. Hewitt;Ute Albrecht;Melvin E. Andersen

  • A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans.

    John C. Ramsey;Melvin E. Andersen

  • Physiologically based pharmacokinetics and the risk assessment process for methylene chloride

    M.E. Andersen;H.J. Clewell;M.L. Gargas;F.A. Smith

  • Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion

    Jingbo Pi;Yushi Bai;Qiang Zhang;Victoria Wong

  • Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

    Michael L. Gargas;Robert J. Burgess;Dale E. Voisard;Gregory H. Cason

  • Human exposure and internal dose assessments of acrylamide in food

    E. Dybing;P.B. Farmer;M. Andersen;T.R. Fennell

  • Inhaled carbon nanotubes reach the subpleural tissue in mice

    Jessica P. Ryman-Rasmussen;Mark F. Cesta;Mark F. Cesta;Mark F. Cesta;Arnold R. Brody;Jeanette K. Shipley-Phillips

  • Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment.

    Barbara A. Wetmore;John F. Wambaugh;Stephen S. Ferguson;Mark A. Sochaski

  • Organotypic liver culture models: Meeting current challenges in toxicity testing

    Edward L. LeCluyse;Rafal P. Witek;Melvin E. Andersen;Mark J. Powers

  • ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

    Jingbo Pi;Qiang Zhang;Jingqi Fu;Jingqi Fu;Courtney G. Woods;Courtney G. Woods

  • Toxicity Testing in the 21st Century: Bringing the Vision to Life

    Melvin E. Andersen;Daniel Krewski

  • Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action

    Melvin E. Andersen;John L. Butenhoff;Shu Ching Chang;David G. Farrar

  • Risk assessment extrapolations and physiological modeling.

    Harvey J. Clewell;Melvin E. Andersen

  • Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening

    Daniel M. Rotroff;Daniel M. Rotroff;Barbara A. Wetmore;David J. Dix;Stephen S. Ferguson

  • Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives

    D. Krewski;M. E. Andersen;M. G. Tyshenko;K. Krishnan

  • Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework

    Russell S. Thomas;Martin A. Philbert;Scott S. Auerbach;Barbara A. Wetmore

  • Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

    Barbara A. Wetmore;John F. Wambaugh;Brittany Allen;Stephen S. Ferguson

  • Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys--probing the determinants of long plasma half-lives.

    Melvin E. Andersen;Harvey J. Clewell;Yu-Mei Tan;John L. Butenhoff

  • A systems biology perspective on Nrf2-mediated antioxidant response.

    Qiang Zhang;Jingbo Pi;Courtney G. Woods;Melvin E. Andersen

Frequent Co-Authors

Jingbo Pi
Jingbo Pi China Medical University
David C. Dorman
David C. Dorman North Carolina State University
Daniel Krewski
Daniel Krewski University of Ottawa
Thomas Hartung
Thomas Hartung Johns Hopkins University
Edward L. LeCluyse
Edward L. LeCluyse Research Triangle Park Foundation
Kim Boekelheide
Kim Boekelheide Brown University
Justin G. Teeguarden
Justin G. Teeguarden Pacific Northwest National Laboratory
Norbert E. Kaminski
Norbert E. Kaminski Michigan State University
Albert J. Fornace
Albert J. Fornace Georgetown University
Sheila Collins
Sheila Collins Vanderbilt University Medical Center

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