World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
107
Citations
37077
World Ranking
283
National Ranking
130

Medicine

D-Index
123
Citations
49617
World Ranking
3377
National Ranking
1857

Overview

Thomas Hartung is affiliated with Johns Hopkins University in the United States. Their research spans multiple disciplines within biomedical sciences, focusing significantly on toxicology, molecular biology, and neuroscience.

Their recent publications cover a range of topics including human regulatory toxicology, brain organoids, and the impact of the COVID-19 pandemic on alcohol consumption. Notable works include:

  • New approach methodologies in human regulatory toxicology - Not if, but how and when! (2023, Environment International)
  • Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish (2023, Frontiers in Science)
  • COVID-19 pandemic and alcohol consumption: Impacts and interconnections (2021, Toxicology Reports)
  • Shell microelectrode arrays (MEAs) for brain organoids (2022, Science Advances)
  • C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly (2021, Cell Metabolism)

Hartung collaborates frequently with several researchers, including:

  • Lena Smirnova
  • Alexandra Maertens
  • Marcel Leist
  • Mathieu Vinken
  • Helena T. Högberg

The scientist has published extensively in several prominent venues with repeated contributions to:

  • ALTEX
  • Archives of Toxicology
  • Evidence-Based Toxicology
  • Toxicology Letters
  • Frontiers in Artificial Intelligence

Key fields of study for this researcher include molecular biology, small animal studies, health, toxicology and mutagenesis, biomedical engineering, and cellular and molecular neuroscience.

Their main research interests encompass:

  • Animal testing and alternatives
  • Computational drug discovery methods
  • 3D printing in biomedical research
  • Neuroscience and neural engineering
  • Pluripotent stem cells research
  • Health, environment, cognitive aging
  • Effects and risks of endocrine disrupting chemicals

Best Publications

  • CD36 is a sensor of diacylglycerides

    Kasper Hoebe;Philippe Georgel;Sophie Rutschmann;Xin Du

  • Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.

    Nicolas W.J. Schröder;Siegfried Morath;Christian Alexander;Lutz Hamann

  • Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells

    Mihai G. Netea;Roger Sutmuller;Corinna Hermann;Chantal A. A. Van der Graaf

  • Innate immunity in Arabidopsis thaliana: lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes.

    Dana Zeidler;Ulrich Zähringer;Isak Gerber;Ian Dubery

  • Toxicology for the twenty-first century

    Thomas Hartung

  • Structure-function relationship of cytokine induction by lipoteichoic acid from Staphylococcus aureus.

    Siegfried Morath;Armin Geyer;Thomas Hartung

  • Membrane Sorting of Toll-like Receptor (TLR)-2/6 and TLR2/1 Heterodimers at the Cell Surface Determines Heterotypic Associations with CD36 and Intracellular Targeting *

    Martha Triantafilou;Frederick G.J. Gamper;Rowenna M. Haston;Marios Angelos Mouratis

  • Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

    Aleksander Skardal;Aleksander Skardal;Sean V. Murphy;Mahesh Devarasetty;Mahesh Devarasetty;Ivy Mead

  • Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids.

    Corinne Grangette;Sophie Nutten;Sophie Nutten;Emmanuelle Palumbo;Siegfried Morath

  • Prevalence of Borrelia burgdorferi sensu lato genospecies in Ixodes ricinus ticks in Europe : a metaanalysis

    Carolin Rauter;Thomas Hartung

  • Guidance on good cell culture practice. a report of the second ECVAM task force on good cell culture practice.

    Sandra Coecke;Michael Balls;Gerard Bowe;John Davis

  • The Role of Toll-like Receptors (TLRs) in Bacteria-induced Maturation of Murine Dendritic Cells (DCs) PEPTIDOGLYCAN AND LIPOTEICHOIC ACID ARE INDUCERS OF DC MATURATION AND REQUIRE TLR2

    Kathrin S. Michelsen;Alexandra Aicher;Mariette Mohaupt;Thomas Hartung

  • Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts

    Alexandra Pfeiffer;Alfred Böttcher;Evelyn Orsó;Michael Kapinsky

  • Interleukin-10 Counterregulates Proinflammatory Cytokine-Induced Inhibition of Neutrophil Apoptosis During Severe Sepsis

    Marius Keel;Udo Ungethüm;Udo Ungethüm;Ursula Steckholzer;Ursula Steckholzer;Eva Niederer;Eva Niederer

  • Adverse outcome pathways: opportunities, limitations and open questions.

    Marcel Leist;Ahmed Ghallab;Ahmed Ghallab;Rabea Graepel;Rosemarie Marchan

  • Induction of Cross-Tolerance by Lipopolysaccharide and Highly Purified Lipoteichoic Acid Via Different Toll-Like Receptors Independent of Paracrine Mediators

    Martin D. Lehner;Siegfried Morath;Kathrin S. Michelsen;Ralf R. Schumann

  • Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

    Knut Erik Tollefsen;Stefan Scholz;Mark T. Cronin;Stephen W. Edwards

  • A modular approach to the ECVAM principles on test validity.

    Thomas Hartung;Susanne Bremer;Silvia Casati;Sandra Coecke

  • L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement

    Nicholas J. Lynch;Silke Roscher;Thomas Hartung;Siegfried Morath

  • Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release

    Siegfried Morath;Andreas Stadelmaier;Armin Geyer;Richard R. Schmidt

  • Toll-like Receptor-2 Mediates Treponema Glycolipid and Lipoteichoic Acid-induced NF-κB Translocation

    Bastian Opitz;Nicolas W.J. Schröder;Ingo Spreitzer;Kathrin S. Michelsen

  • Guidance on Good Cell Culture Practice

    Sandra Coecke;Michael Balls;Gerard Bowe;John Davis

Frequent Co-Authors

Albrecht Wendel
Albrecht Wendel University of Konstanz
Marcel Leist
Marcel Leist University of Konstanz
Melvin E. Andersen
Melvin E. Andersen Research Triangle Park Foundation
Richard R. Schmidt
Richard R. Schmidt University of Konstanz
Hao Zhu
Hao Zhu Rutgers, The State University of New Jersey
Kevin M. Crofton
Kevin M. Crofton R3Fellows LLC
Mark T. D. Cronin
Mark T. D. Cronin Liverpool John Moores University
Ian Kimber
Ian Kimber University of Manchester
Thomas B. Knudsen
Thomas B. Knudsen Environmental Protection Agency
David A. Basketter
David A. Basketter University of Bedfordshire

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