Marcel Leist

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Germany Leader Award
• 2025 - Research.com Biology and Biochemistry in Germany Leader Award
• 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Best Publications

• Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

  Marcel Leist;Barbara Single;Anna F. Castoldi;Simone Kühnle

  2402
  Citations

• Four deaths and a funeral: from caspases to alternative mechanisms.

  Marcel Leist;Marja Jäättelä

  2268
  Citations

• Derivatives of Erythropoietin That Are Tissue Protective But Not Erythropoietic

  Marcel Leist;Pietro Ghezzi;Giovanni Grasso;Giovanni Grasso;Roberto Bianchi

  1003
  Citations

• Lysosomes in cell death

  Maria Eugenia Guicciardi;Marcel Leist;Gregory J Gores

  874
  Citations

• Cathepsin B Acts as a Dominant Execution Protease in Tumor Cell Apoptosis Induced by Tumor Necrosis Factor

  Lasse Foghsgaard;Dorte Wissing;Daniel Mauch;Ulrik Lademann

  819
  Citations

• The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation.

  Anja Henn;Søren Lund;Maj Hedtjärn;Andreé Schrattenholz

  768
  Citations

• Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.

  Marcel Leist;Florian Gantner;Ines Bohlinger;Gisa Tiegs

  694
  Citations

• Concanavalin A - induced T-cell - mediated hepatic injury in mice : The role of tumor necrosis factor

  Florian Gantner;Marcel Leist;I Ansgar Wilhelm Lohse;Paul Georg Germann

  628
  Citations

• Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest.

  Marcel Leist;Florian Gantner;Ines Bohlinger;Paul G. Germann

  614
  Citations

• Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.

  Serhat Erbayraktar;Giovanni Grasso;Giovanni Grasso;Alessandra Sfacteria;Alessandra Sfacteria;Qiao wen Xie

  579
  Citations

• Intracellular ATP, a switch in the decision between apoptosis and necrosis.

  Pierluigi Nicotera;Marcel Leist;Elisa Ferrando-May

  474
  Citations

• Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells.

  Marianne Suter;Charlotte E. Reme;Christian Grimm;Andreas Wenzel

  465
  Citations

• The Shape of Cell Death

  Marcel Leist;Pierluigi Nicotera

  445
  Citations

• Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release.

  Marcel Leist;Florian Gantner;Sabine Jilg;Albrecht Wendel

  422
  Citations

• Apoptosis, Excitotoxicity, and Neuropathology

  Marcel Leist;Pierluigi Nicotera

  405
  Citations

• Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis.

  Marcel Leist;Barbara Single;Heike Naumann;Eugenio Fava

  357
  Citations

• Caspase inhibition reduces apoptosis and increases survival of nigral transplants

  Gabriele S. Schierle;Oskar Hansson;Marcel Leist;Pierluigi Nicotera

  355
  Citations

• NEURONAL CELL DEATH : A DEMISE WITH DIFFERENT SHAPES

  Pierluigi Nicotera;Marcel Leist;Luigi Manzo

  351
  Citations

• Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway.

  Julie Lotharius;Jeppe Falsig;Johan van Beek;Sarah Payne

  350
  Citations

• Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line

  Diana Scholz;Dominik Pöltl;Andreas Genewsky;Matthias Weng

  348
  Citations