What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Apoptosis, Cell biology, Programmed cell death, Tumor necrosis factor alpha and Necrosis.
Many of his studies on Apoptosis apply to Molecular biology as well.
His Cell biology research is multidisciplinary, incorporating perspectives in Cell, Cell culture, Neurodegeneration and Microglia.
His research in Programmed cell death intersects with topics in Heat shock protein, Neuroscience, Nervous system and Mitochondrion.
His Tumor necrosis factor alpha research incorporates themes from Cancer research, Liver injury and In vivo.
His biological study spans a wide range of topics, including Proteases, Cathepsin, Poly ADP ribose polymerase and Lysosome.
His most cited work include:
- Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis (1659 citations)
- Four deaths and a funeral: from caspases to alternative mechanisms. (1471 citations)
- Derivatives of Erythropoietin That Are Tissue Protective But Not Erythropoietic (724 citations)
What are the main themes of his work throughout his whole career to date?
Marcel Leist mostly deals with Cell biology, Apoptosis, Programmed cell death, Pharmacology and Neuroscience.
Marcel Leist has included themes like Embryonic stem cell and Cell in his Cell biology study.
He interconnects Necrosis, Molecular biology and Tumor necrosis factor alpha in the investigation of issues within Apoptosis.
The concepts of his Tumor necrosis factor alpha study are interwoven with issues in Lipopolysaccharide, Cancer research and Cytokine.
His studies deal with areas such as Neurotoxicity, Toxicity and In vivo as well as Pharmacology.
His Neuroprotection research includes elements of Excitotoxicity and Erythropoietin.
He most often published in these fields:
- Cell biology (33.98%)
- Apoptosis (20.96%)
- Programmed cell death (15.18%)
What were the highlights of his more recent work (between 2018-2021)?
- Pharmacology (10.84%)
- Neurotoxicity (6.02%)
- Toxicity (6.75%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Pharmacology, Neurotoxicity, Toxicity, Cell biology and Biochemistry.
Marcel Leist has included themes like METABOLIC FEATURES, Stage specific and Toxicant in his Pharmacology study.
His Neurotoxicity research also works with subjects such as
- Neurite, which have a strong connection to Blood–brain barrier, Neuroprotection, Neurodegeneration, Dopaminergic and Cell,
- Nervous system which intersects with area such as Allosteric modulator and Mecamylamine.
Marcel Leist combines subjects such as Food additive, Prolonged exposure, Toxicology and In vivo with his study of Toxicity.
In the field of Cell biology, his study on Stem cell overlaps with subjects such as Quinolinic acid.
The Cytotoxicity study combines topics in areas such as Cancer cell, Apoptosis, Glycosylation and Phosphatidylserine.
Between 2018 and 2021, his most popular works were:
- Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations (40 citations)
- Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development (32 citations)
- The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity. (22 citations)
In his most recent research, the most cited papers focused on:
Marcel Leist spends much of his time researching Toxicity, Human health, Test, Software engineering and Computational biology.
His Toxicity study integrates concerns from other disciplines, such as Mitochondrial respiratory chain complex I, Pharmacology, In vivo and Cmax.
His study in Pharmacology is interdisciplinary in nature, drawing from both Membrane potential, Antimycin A, Mitochondrion and Coenzyme Q – cytochrome c reductase.
His Test study combines topics from a wide range of disciplines, such as Test data generation, Metadata and Strategy implementation.
His research in Computational biology intersects with topics in Developmental neurotoxicity, Hazard analysis, Workflow and In silico.
His Cell type research integrates issues from Succinate dehydrogenase, Neurodegeneration, Microglia and Neuroscience, Neuroprotection.
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