D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 77 Citations 19,058 371 World Ranking 3028 National Ranking 222

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Cancer

Jürgen Hescheler mainly investigates Cell biology, Embryonic stem cell, Embryoid body, Molecular biology and Stem cell. Jürgen Hescheler combines subjects such as Endocrinology, Internal medicine and Anatomy with his study of Cell biology. His study in Embryonic stem cell is interdisciplinary in nature, drawing from both Neuroscience, Cellular differentiation, Transplantation and Green fluorescent protein.

His Embryoid body study integrates concerns from other disciplines, such as Angiogenesis, Hyperpolarization, Free radical scavenger, Retinoic acid and Myosin. His Molecular biology research includes themes of Cell, Signal transduction, ChIP-on-chip, Chromatin remodeling and Kinase. His research integrates issues of Adult stem cell, Embryonic Stage, Immunology, Pathology and Developmental biology in his study of Stem cell.

His most cited work include:

  • Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. (956 citations)
  • Retinoic Acid Accelerates Embryonic Stem Cell-Derived Cardiac Differentiation and Enhances Development of Ventricular Cardiomyocytes ☆ (452 citations)
  • Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins (361 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Embryonic stem cell, Stem cell, Internal medicine and Molecular biology are his primary areas of study. His work in Cell biology addresses issues such as Induced pluripotent stem cell, which are connected to fields such as Pharmacology. Jürgen Hescheler works in the field of Embryonic stem cell, focusing on Embryoid body in particular.

He has researched Stem cell in several fields, including Pathology and KOSR, Adult stem cell. His Internal medicine research is multidisciplinary, relying on both Endocrinology and Cardiology. Jürgen Hescheler studied Endocrinology and Patch clamp that intersect with Membrane potential.

He most often published in these fields:

  • Cell biology (43.33%)
  • Embryonic stem cell (34.87%)
  • Stem cell (22.31%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (43.33%)
  • Induced pluripotent stem cell (16.41%)
  • Embryonic stem cell (34.87%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Induced pluripotent stem cell, Embryonic stem cell, Stem cell and Pharmacology. His biological study spans a wide range of topics, including Genetics, Cellular differentiation and Bioreactor. His Cellular differentiation research includes themes of microRNA and Homeobox protein NANOG.

His study on Induced pluripotent stem cell also encompasses disciplines like

  • Cytotoxicity, Doxorubicin, Ion homeostasis and Electrophysiology most often made with reference to Cardiotoxicity,
  • Cell, which have a strong connection to Cell culture,
  • In vivo, which have a strong connection to Transplantation. He mostly deals with Embryoid body in his studies of Embryonic stem cell. His research investigates the link between Stem cell and topics such as Cancer research that cross with problems in Inflammation.

Between 2015 and 2021, his most popular works were:

  • Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment. (60 citations)
  • MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes (50 citations)
  • Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience (36 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Jürgen Hescheler focuses on Induced pluripotent stem cell, Pharmacology, Cell biology, Stem cell and Cardiotoxicity. His Cell biology research includes elements of Cell, Cardiac fibrosis and Somatic cell. His work deals with themes such as Embryonic stem cell, Transcriptome, Cellular differentiation and Embryoid body, which intersect with Stem cell.

Jürgen Hescheler applies his multidisciplinary studies on Embryonic stem cell and Human safety in his research. His study focuses on the intersection of Cellular differentiation and fields such as microRNA with connections in the field of Molecular biology, Histone acetyltransferase, HAT1, Epigenetics and DNMT3B. His biological study spans a wide range of topics, including Homeobox protein NANOG, KOSR and P19 cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation.

Jens Martin Nygren;Stefan Jovinge;Martin Breitbach;Petter Säwén.
Nature Medicine (2004)

1378 Citations

Retinoic Acid Accelerates Embryonic Stem Cell-Derived Cardiac Differentiation and Enhances Development of Ventricular Cardiomyocytes ☆

Anna M. Wobus;Guan Kaomei;Jin Shan;Marie-Cecile Wellner.
Journal of Molecular and Cellular Cardiology (1997)

592 Citations

Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins

Christiane Kleuss;Hans Scherübl;Jürgen Hescheler;Günter Schultz.
Science (1993)

531 Citations

Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons

Carsten Strübing;Gudrun Ahnert-Hilger;Jin Shan;Bertram Wiedenmann.
Mechanisms of Development (1995)

530 Citations

Host-dependent tumorigenesis of embryonic stem cell transplantation in experimental stroke.

Franciska Erdö;Christian Bührle;James Blunk;Mathias Hoehn.
Journal of Cerebral Blood Flow and Metabolism (2003)

448 Citations

Engraftment of engineered ES cell–derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium

Eugen Kolossov;Toktam Bostani;Wilhelm Roell;Martin Breitbach.
Journal of Experimental Medicine (2006)

425 Citations

Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species

Maria Wartenberg;Frederike C. Ling;Markus Müschen;Florian Klein.
The FASEB Journal (2003)

392 Citations

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

Qiangzhe Zhang;Junjie Jiang;Pengcheng Han;Qi Yuan.
Cell Research (2011)

355 Citations

Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells.

Heinrich Sauer;Gohar Rahimi;Jürgen Hescheler;Maria Wartenberg.
FEBS Letters (2000)

351 Citations

Cardiac specific differentiation of mouse embryonic stem cells

Agapios Sachinidis;Bernd K Fleischmann;Eugen Kolossov;Maria Wartenberg.
Cardiovascular Research (2003)

327 Citations

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