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Molecular Biology

D-Index
42
Citations
8091
World Ranking
3014
National Ranking
206

Overview

Tomo Saric is affiliated with the University of Cologne in Germany and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans various subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Surgery, Cell Biology, and Orthopedics and Sports Medicine.

The scientist's research focuses on topics such as Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Cardiovascular Effects of Exercise, Congenital Heart Defects Research, Cardiomyopathy and Myosin Studies, Tissue Engineering and Regenerative Medicine, and Neuroscience and Neural Engineering.

They have contributed to multiple recent papers, including:

  • Metabolic Maturation Increases Susceptibility to Hypoxia-induced Damage in Human iPSC-derived Cardiomyocytes, 2022, Stem Cells Translational Medicine
  • Co-transplantation of Mesenchymal Stromal Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improves Cardiac Function After Myocardial Damage, 2022, Frontiers in Cardiovascular Medicine
  • Small molecule-mediated rapid maturation of human induced pluripotent stem cell-derived cardiomyocytes, 2022, Stem Cell Research & Therapy
  • Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations, 2021, Scientific Reports
  • Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages, 2021, Stem Cell Research & Therapy

Frequent co-authors working alongside Saric include Jürgen Hescheler, Konstanze Stangner, Soumyata Pathak, Ruth Biller, and Sunil Yeruva.

The scientist's publications appear frequently in these venues:

  • Stem Cell Research & Therapy
  • International Journal of Molecular Sciences
  • Stem Cell Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of Anatomy - Anatomischer Anzeiger

Best Publications

  • An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides.

    Tomo Saric;Shih-Chung Chang;Akira Hattori;Ian A. York

  • The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues.

    Ian A. York;Shih-Chung Chang;Tomo Saric;Jennifer A. Keys

  • The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

    Alfred L Goldberg;Paolo Cascio;Tomo Saric;Kenneth L Rock

  • Protein degradation and the generation of MHC class I-presented peptides

    Kenneth L Rock;Ian A York;Tomo Saric;Alfred L Goldberg

  • CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition.

    Michael S von Bergwelt-Baildon;Alexey Popov;Tomo Saric;Jens M Chemnitz

  • Pathway for Degradation of Peptides Generated by Proteasomes A KEY ROLE FOR THIMET OLIGOPEPTIDASE AND OTHER METALLOPEPTIDASES

    Tomo Saric;Claudia I. Graef;Alfred L. Goldberg

  • CPAP promotes timely cilium disassembly to maintain neural progenitor pool

    Elke Gabriel;Arpit Wason;Anand Ramani;Li Ming Gooi

  • Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells.

    Joana Frobel;Hatim Hemeda;Michael Lenz;Giulio Abagnale

  • In vitro Modeling of Ryanodine Receptor 2 Dysfunction Using Human Induced Pluripotent Stem Cells

    Azra Fatima;Guoxing Xu;Kaifeng Shao;Symeon Papadopoulos

  • Research and therapy with induced pluripotent stem cells (iPSCs): social, legal, and ethical considerations

    Sharif Moradi;Hamid Mahdizadeh;Tomo Šarić;Johnny Kim

  • Major Histocompatibility Complex Class I-presented Antigenic Peptides Are Degraded in Cytosolic Extracts Primarily by Thimet Oligopeptidase

    Tomo Saric;Jochen Beninga;Claudia I. Graef;Tatos N. Akopian

  • Indoleamine 2,3-dioxygenase–expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection

    Alexey Popov;Zeinab Abdullah;Claudia Wickenhauser;Tomo Saric

  • Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro

    Alexey Kuzmenkin;Huamin Liang;Huamin Liang;Guoxing Xu;Guoxing Xu;Kurt Pfannkuche

  • Pluripotent stem cells escape from senescence-associated DNA methylation changes

    Carmen M Koch;Kristina Reck;Kaifeng Shao;Qiong Lin

  • Ca2+ signaling in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CM) from normal and catecholaminergic polymorphic ventricular tachycardia (CPVT)-afflicted subjects.

    X.-H. Zhang;S. Haviland;H. Wei;T. Šarić

  • Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility

    Kurt Pfannkuche;Huamin Liang;Tobias Hannes;Jiaoya Xi

  • Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells

    Jiaoya Xi;Markus Khalil;Nava Shishechian;Tobias Hannes

  • Genetic pattern of prostate cancer progression.

    Tomo Saric;Zoran Brkanac;Dean A. Troyer;Susan S. Padalecki

  • Preparation of cardiac extracellular matrix scaffolds by decellularization of human myocardium: Human Myocardial Ecm

    Barbara Oberwallner;Andreja Brodarac;Yeong-Hoon Choi;Tomo Saric

  • Preparation of cardiac extracellular matrix scaffolds by decellularization of human myocardium.

    Barbara Oberwallner;Andreja Brodarac;Yeong-Hoon Choi;Tomo Saric

Frequent Co-Authors

Jürgen Hescheler
Jürgen Hescheler University of Cologne
Alfred L. Goldberg
Alfred L. Goldberg Harvard University
Kenneth L. Rock
Kenneth L. Rock University of Massachusetts Chan Medical School
Martin Zenke
Martin Zenke RWTH Aachen University
Hossein Baharvand
Hossein Baharvand Royan Institute
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Hans Christian Hennies
Hans Christian Hennies University of Huddersfield
Agapios Sachinidis
Agapios Sachinidis University of Cologne
Wilhelm Bloch
Wilhelm Bloch German Sport University Cologne
Martin Krönke
Martin Krönke University of Cologne

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