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Biology and Biochemistry

D-Index
68
Citations
16188
World Ranking
7805
National Ranking
30

Overview

Paula M. Alves is affiliated with Universidade Nova de Lisboa in Portugal. Their research predominantly lies at the intersection of biochemistry, genetics, molecular biology, and medicine, with a total of 122 publications in Biochemistry, Genetics and Molecular Biology and 116 in Medicine. This work spans several subfields including molecular biology, genetics, biomedical engineering, infectious diseases, and oncology.

The scientist has contributed to numerous topics with a focus on viral infectious diseases and gene expression in insects, virus-based gene therapy research, 3D printing in biomedical research, tissue engineering and regenerative medicine, SARS-CoV-2 and COVID-19 research, transgenic plants and applications, as well as extracellular vesicles in disease.

Recent publications by Paula M. Alves include the following:

  • Next generation of heart regenerative therapies: progress and promise of cardiac tissue engineering, 2021, npj Regenerative Medicine
  • Functionalizing Ferritin Nanoparticles for Vaccine Development, 2021, Pharmaceutics
  • Advances in Lentivirus Purification, 2020, Biotechnology Journal
  • Bioactivity and miRNome Profiling of Native Extracellular Vesicles in Human Induced Pluripotent Stem Cell-Cardiomyocyte Differentiation, 2022, Advanced Science
  • Production of high-quality SARS-CoV-2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance, 2021, Biotechnology and Bioengineering

Collaborations have been a notable aspect of their career, frequently working alongside António Roldão, Margarida Serra, Catarina Brito, Patrícia Gomes-Alves, and Ricardo Correia, with each coauthor contributing to multiple projects. This network of collaboration highlights the interdisciplinary nature of their research.

Paula M. Alves has published extensively in several prominent venues, including:

  • Biotechnology and Bioengineering
  • Frontiers in Bioengineering and Biotechnology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytotherapy
  • Biotechnology Journal

Best Publications

  • Virus-like particles in vaccine development

    António Roldão;Maria Candida M Mellado;Leda R Castilho;Manuel J T Carrondo

  • Process engineering of human pluripotent stem cells for clinical application.

    Margarida Serra;Catarina Brito;Cláudia Correia;Paula M. Alves

  • Large-scale production and purification of VLP-based vaccines.

    Tiago Vicente;António Roldão;Cristina Peixoto;Manuel José Teixeira Carrondo

  • Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing.

    Rui M. Tostões;Sofia B. Leite;Margarida Serra;Janne Jensen

  • Advances in on-line monitoring and control of mammalian cell cultures: Supporting the PAT initiative.

    A.P. Teixeira;R. Oliveira;P.M. Alves;M.J.T. Carrondo

  • Effects of ammonia and lactate on growth, metabolism, and productivity of BHK cells.

    H.J Cruz;C.M Freitas;P.M Alves;J.L Moreira

  • Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells.

    Cláudia Correia;Alexey Koshkin;Patrícia Duarte;Dongjian Hu

  • Microencapsulation technology: a powerful tool for integrating expansion and cryopreservation of human embryonic stem cells.

    Margarida Serra;Cláudia Correia;Rita Malpique;Catarina Brito

  • Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species.

    Helena L.A. Vieira;Paula M. Alves;Alessandro Vercelli

  • 3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment.

    Sofia P. Rebelo;Catarina Pinto;Tatiana R. Martins;Nathalie Harrer

  • Metabolic Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes by Inhibition of HIF1α and LDHA.

    Dongjian Hu;Dongjian Hu;Annet Linders;Annet Linders;Abir Yamak;Cláudia Correia

  • A multi-organ chip co-culture of neurospheres and liver equivalents for long-term substance testing

    Eva-Maria Materne;Anja Patricia Ramme;Ana Paula Terrasso;Margarida Serra

  • Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control

    Margarida Serra;Catarina Brito;Marcos F.Q. Sousa;Janne Jensen

  • Neuroprotective effect of blackberry (Rubus sp.) polyphenols is potentiated after simulated gastrointestinal digestion

    Lucélia Tavares;Inês Figueira;Diana Macedo;Gordon J. McDougall

  • Glutathionylation of Adenine Nucleotide Translocase Induced by Carbon Monoxide Prevents Mitochondrial Membrane Permeabilization and Apoptosis

    Cláudia S.F. Queiroga;Ana S. Almeida;Cécile Martel;Catherine Brenner

  • Downstream processing of triple layered rotavirus like particles.

    C. Peixoto;M.F.Q. Sousa;A.C. Silva;M.J.T. Carrondo

  • Antioxidant properties and neuroprotective capacity of strawberry tree fruit (Arbutus unedo).

    Sofia Fortalezas;Lucélia Tavares;Rui Pimpão;Meenu Tyagi

  • Cell density effect in the baculovirus-insect cells system: a quantitative analysis of energetic metabolism.

    Vicente Bernal;Nuno Carinhas;Adriana Y. Yokomizo;Manuel J.T. Carrondo

  • Triple layered rotavirus VLP production: kinetics of vector replication, mRNA stability and recombinant protein production.

    Helena L.A. Vieira;Catarina Estêvão;António Roldão;Cristina C. Peixoto

  • 3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytes.

    Cláudia Correia;Alexey Koshkin;Patrícia Duarte;Dongjian Hu

Frequent Co-Authors

Manuel J.T. Carrondo
Manuel J.T. Carrondo Universidade Nova de Lisboa
Rui Oliveira
Rui Oliveira University of Minho
Pedro E. Cruz
Pedro E. Cruz University of Florida
Eric J. Kremer
Eric J. Kremer University of Montpellier
Ursula Sonnewald
Ursula Sonnewald Norwegian University of Science and Technology
Udo Reichl
Udo Reichl Otto-von-Guericke University Magdeburg
Nathalie Vachiery
Nathalie Vachiery Animal, Santé, Territoires, Risques et Ecosystèmes
Ana Varela Coelho
Ana Varela Coelho Universidade Nova de Lisboa
Dieter Leibfritz
Dieter Leibfritz University of Bremen
Arthur J. L. Cooper
Arthur J. L. Cooper New York Medical College

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