World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
7709
World Ranking
18095
National Ranking
7396

Overview

Pedro E. Cruz is a researcher affiliated with the University of Florida in the United States, with a primary focus on the field of Medicine. Their research spans several subfields including Surgery, Neurology, Physiology, Molecular Biology, and Genetics. Pedro's scholarly work addresses multiple topics such as Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, long-term effects of COVID-19, virus-based gene therapy research, CRISPR and genetic engineering, Parkinson's disease mechanisms and treatments, and tissue engineering and regenerative medicine.

Their recent scholarly contributions include studies published in a variety of scientific journals. Notable papers include:

  • "Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes" (2020), in Molecular Therapy
  • "The potential of COVID-19 patients' sera to cause antibody-dependent enhancement of infection and IL-6 production" (2021), in Scientific Reports
  • "Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions" (2021), in Acta Neuropathologica
  • "Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS" (2020), in Molecular Neurodegeneration
  • "Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy" (2020), in Molecular Neurobiology

Cruz collaborates frequently with multiple co-authors. Key collaborators include Todd E. Golde, Yona Levites, Carolina Ceballos-Diaz, Daniel Ryu, and Marshall S. Goodwin. These professional relationships reflect interdisciplinary teamwork within the biomedical research community.

Pedro E. Cruz's work has appeared in several publication venues, with multiple articles published in Revista Portuguesa de Estomatologia Medicina Dentária e Cirurgia Maxilofacial and Cureus. Other venues with repeated contributions include Molecular Neurodegeneration, npj Parkinson's Disease, and Frontiers in Cell and Developmental Biology.

The scientist's research integrates experimental studies and clinical investigation to address mechanisms in neurodegenerative diseases and genetic therapies. Themes such as Alzheimer's and Parkinson's disease mechanisms, viral vector gene delivery systems, and the impacts of COVID-19 are prominent in their body of work.

Best Publications

  • IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

    Paramita Chakrabarty;Andrew Li;Carolina Ceballos-Diaz;James A. Eddy

  • α-1 Antitrypsin Inhibits Caspase-3 Activity, Preventing Lung Endothelial Cell Apoptosis

    Irina Petrache;Iwona Fijalkowska;Terry R. Medler;Jarrett Skirball

  • A Novel Antiapoptotic Role for α1-Antitrypsin in the Prevention of Pulmonary Emphysema

    Irina Petrache;Iwona Fijalkowska;Lijie Zhen;Terry R. Medler

  • Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10.

    Erin D Milligan;Evan M Sloane;Stephen J Langer;Pedro E Cruz

  • IL-10 Suppresses Chemokines, Inflammation, and Fibrosis in a Model of Chronic Renal Disease

    Wei Mu;Xiaosen Ouyang;Anupam Agarwal;Li Zhang

  • Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.

    Erin D. Milligan;Evan M. Sloane;Stephen J. Langer;Travis S. Hughes

  • Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain.

    Paramita Chakrabarty;Awilda Rosario;Pedro Cruz;Zoe Siemienski

  • Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing

    Jorge M Santos;Sérgio P Camões;Elysse Filipe;Madalena Cipriano

  • Larval growth and survival of two catarina scallop (Argopecten circularis, Sowerby, 1835) populations and their reciprocal crosses

    Pedro Cruz;Ana M Ibarra

  • Population Genetic Structure of Pacific White Shrimp (Litopenaeus vannamei) from Mexico to Panama: Microsatellite DNA Variation

    R. Valles-Jimenez;P. Cruz;R. Perez-Enriquez

  • Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling after myocardial infarction by proangiogenic, antiapoptotic, and endogenous cell-activation mechanisms.

    Diana Santos Nascimento;Diogo Mosqueira;Luís Moura Sousa;Mariana Teixeira

  • Triple layered rotavirus VLP production: kinetics of vector replication, mRNA stability and recombinant protein production.

    Helena L.A. Vieira;Catarina Estêvão;António Roldão;Cristina C. Peixoto

  • Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway

    Sifeng Chen;Matthias H. Kapturczak;Clive Wasserfall;Olena Y. Glushakova

  • Purification of retroviral vectors for clinical application: biological implications and technological challenges.

    Teresa Rodrigues;Manuel J.T. Carrondo;Paula M. Alves;Pedro E. Cruz

  • Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

    Lorenza Magno;Christian B. Lessard;Marta Martins;Marta Martins;Verena Lang

  • Genetic Variability Assessed by Microsatellites in a Breeding Program of Pacific White Shrimp (Litopenaeus vannamei)

    Pedro Cruz;Ana M. Ibarra;Humberto Mejia-Ruiz;Patrick M. Gaffney

  • Microglia-specific targeting by novel capsid-modified AAV6 vectors

    Awilda M. Rosario;Pedro E. Cruz;Carolina Ceballos-Diaz;Michael R. Strickland

  • High-affinity interactions and signal transduction between Aβ oligomers and TREM2.

    Christian B Lessard;Samuel L Malnik;Yingyue Zhou;Thomas B Ladd

  • Sirtuin 1 Functionally and Physically Interacts with Disruptor of Telomeric Silencing-1 to Regulate α-ENaC Transcription in Collecting Duct

    Dongyu Zhang;Shiyu Li;Pedro Cruz;Bruce C. Kone

  • Realized heritabilities and genetic correlation after dual selection for total weight and shell width in catarina scallop (Argopecten ventricosus)

    Ana M Ibarra;Jose L Ramirez;Cesar A Ruiz;Pedro Cruz

Frequent Co-Authors

Todd E. Golde
Todd E. Golde Emory University
Manuel J.T. Carrondo
Manuel J.T. Carrondo Universidade Nova de Lisboa
Paula M. Alves
Paula M. Alves Universidade Nova de Lisboa
Terence R. Flotte
Terence R. Flotte University of Massachusetts Chan Medical School
Benoit I. Giasson
Benoit I. Giasson University of Florida
David R. Borchelt
David R. Borchelt University of Florida
Hansjörg Hauser
Hansjörg Hauser Helmholtz Centre for Infection Research
Martha Campbell-Thompson
Martha Campbell-Thompson University of Florida
Nathan D. Price
Nathan D. Price University of Illinois at Urbana-Champaign

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