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David R. Borchelt

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
48495
World Ranking
1626
National Ranking
906

David R. Borchelt publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David R. Borchelt sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 311 publications — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David R. Borchelt D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David R. Borchelt sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 98 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David R. Borchelt is affiliated with the University of Florida in the United States. Their research primarily focuses on the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology. Within these broad domains, their work delves into subfields including neurology, physiology, molecular biology, cellular and molecular neuroscience, and pharmacology.

The main topics addressed in their research include:

  • Alzheimer's disease research and treatments
  • Prion diseases and protein misfolding
  • Amyotrophic lateral sclerosis research
  • Neuroinflammation and neurodegeneration mechanisms
  • Cholinesterase and neurodegenerative diseases
  • Neurogenetic and muscular disorders research
  • Parkinson's disease mechanisms and treatments

David R. Borchelt has published multiple papers in a variety of scientific venues. Some recent papers include:

  • "Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease" (2020), published in Molecular Neurodegeneration
  • "Reactive astrocytes as treatment targets in Alzheimer's disease-Systematic review of studies using the APPswePS1dE9 mouse model" (2021), published in Glia
  • "Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis" (2022), published in Molecular Neurodegeneration
  • "Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection" (2020), published in PLoS ONE
  • "Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease" (2024), published in Cell Reports Medicine

The scientist collaborates frequently with other researchers, including:

  • Paramita Chakrabarty
  • Guilian Xu
  • Susan Fromholt
  • Benoit I. Giasson
  • Stefan Prokop

David R. Borchelt's work has been published often in several scientific venues, particularly:

  • Acta Neuropathologica Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Neurodegeneration
  • Alzheimer s & Dementia
  • Glia

Best Publications

  • APP processing and synaptic function.

    Flavio Kamenetz;Taisuke Tomita;Helen Hsieh;Helen Hsieh;Guy Seabrook

  • Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

    David R. Borchelt;Gopal Thinakaran;Christopher B. Eckman;Christopher B. Eckman;Michael K. Lee

  • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

    Philip C Wong;Carlos A Pardo;David R Borchelt;Michael K Lee

  • Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

    Joanna L. Jankowsky;Joanna L. Jankowsky;Daniel J. Fadale;Jeffrey Anderson;Guilian M. Xu

  • ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions

    L. I. Bruijn;M. W. Becher;M. K. Lee;K. L. Anderson

  • BACE1 is the major beta-secretase for generation of Abeta peptides by neurons.

    Huaibin Cai;Yanshu Wang;Diane McCarthy;Hongjin Wen

  • Scrapie prion protein contains a phosphatidylinositol glycolipid

    Neil Stahl;David R. Borchelt;Karen Hsiao;Stanley B. Prusiner

  • Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

    David R Borchelt;Tamara Ratovitski;Judy van Lare;Michael K Lee

  • ENDOPROTEOLYSIS OF PRESENILIN 1 AND ACCUMULATION OF PROCESSED DERIVATIVES IN VIVO

    Gopal Thinakaran;David R Borchelt;Michael K Lee;Hilda H Slunt

  • Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium Hydroxide

    Daniel Krewski;Robert A Yokel;Evert Nieboer;David Borchelt

  • Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin

    Gabriele Schilling;Mark W. Becher;Alan H. Sharp;Hyder A. Jinnah

  • Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

    Joanna L Jankowsky;Hilda H Slunt;Tamara Ratovitski;Nancy A Jenkins

  • Decreased expression of striatal signaling genes in a mouse model of Huntington’s disease

    Ruth Luthi-Carter;Andrew Strand;Nikki L. Peters;Steven M. Solano

  • Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

    David R. Borchelt;Michael K. Lee;Hilda S. Slunt;Michael Guarnieri

  • Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.

    David R. Borchelt;Michael Scott;Albert Taraboulos;Neff Stahl

  • BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions

    Fiona M. Laird;Huaibin Cai;Alena V. Savonenko;Mohamed H. Farah

  • Age-Related CNS Disorder and Early Death in Transgenic FVB/N Mice Overexpressing Alzheimer Amyloid Precursor Proteins

    Karen K. Hsiao;David R. Borchelt;Kristine Olson;Rosa Johannsdottir

  • Evidence for synthesis of scrapie prion proteins in the endocytic pathway.

    D R Borchelt;A Taraboulos;S B Prusiner

  • Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease.

    Joanna L. Jankowsky;Joanna L. Jankowsky;Tatiana Melnikova;Daniel J. Fadale;Guilian M. Xu

  • Alzheimer's disease: genetic studies and transgenic models.

    Donald L. Price;Rudolph E. Tanzi;David R. Borchelt;Sangram S. Sisodia

Frequent Co-Authors

Donald L. Price
Donald L. Price Johns Hopkins University
Sangram S. Sisodia
Sangram S. Sisodia University of Chicago
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Philip C. Wong
Philip C. Wong Johns Hopkins University School of Medicine
Todd E. Golde
Todd E. Golde Emory University
Christopher A. Ross
Christopher A. Ross Johns Hopkins University School of Medicine
Gopal Thinakaran
Gopal Thinakaran University of Chicago
Alena Savonenko
Alena Savonenko Johns Hopkins University School of Medicine
Don W. Cleveland
Don W. Cleveland University of California, San Diego

External Links

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Related Online Degrees & Career Pathways

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For those looking for flexibility, consider pursuing a health information management online degree. These programs offer a cost-effective, accessible way to gain essential skills for numerous career options within the healthcare sector.

Best Scientists Citing David R. Borchelt

Stanley B. Prusiner

Stanley B. Prusiner

University of California, San Francisco

Publications: 191

Christian Haass

Christian Haass

Ludwig-Maximilians-Universität München

Publications: 124

Mark P. Mattson

Mark P. Mattson

Johns Hopkins University

Publications: 115

Todd E. Golde

Todd E. Golde

Emory University

Publications: 100

Bart De Strooper

Bart De Strooper

KU Leuven

Publications: 99

Bradley T. Hyman

Bradley T. Hyman

Harvard University

Publications: 97

Don W. Cleveland

Don W. Cleveland

University of California, San Diego

Publications: 92

M. Flint Beal

M. Flint Beal

Cornell University

Publications: 91

Michael R. Hayden

Michael R. Hayden

University of British Columbia

Publications: 87

David M. Holtzman

David M. Holtzman

Washington University in St. Louis

Publications: 82

Dennis J. Selkoe

Dennis J. Selkoe

Brigham and Women's Hospital

Publications: 81

Sangram S. Sisodia

Sangram S. Sisodia

University of Chicago

Publications: 80

Heikki Tanila

Heikki Tanila

University of Eastern Finland

Publications: 78

Peter St George-Hyslop

Peter St George-Hyslop

Columbia University

Publications: 76

Paul E. Fraser

Paul E. Fraser

University of Toronto

Publications: 75

Huaxi Xu

Huaxi Xu

Xiamen University

Publications: 75

Trending Scientists

Yong Zhang

Yong Zhang

University of North Carolina at Charlotte

Jason P. Connor

Jason P. Connor

University of Queensland

Karen L. Cropsey

Karen L. Cropsey

University of Alabama at Birmingham

Erik T. Buitenhuis

Erik T. Buitenhuis

University of East Anglia

Carlos A. Arias

Carlos A. Arias

Aarhus University

Huiru Tang

Huiru Tang

Fudan University

Fred Chang

Fred Chang

University of California, San Francisco

Rajiv N. Rimal

Rajiv N. Rimal

Johns Hopkins University

Edward R. Sherwood

Edward R. Sherwood

Vanderbilt University Medical Center

Niels Ødum

Niels Ødum

University of Copenhagen

Philip Doble

Philip Doble

University of Technology Sydney

Thierry Besson

Thierry Besson

University of Rouen

Vernon L. Smith

Vernon L. Smith

Chapman University

Stefan Michiels

Stefan Michiels

University of Paris-Saclay

Kjell Någren

Kjell Någren

Odense University Hospital

Ulrich Gabbert

Ulrich Gabbert

Otto-von-Guericke University Magdeburg

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