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Thierry Besson

Thierry Besson

D-Index & Metrics

Chemistry

D-Index
45
Citations
5336
World Ranking
16625
National Ranking
729

Overview

Thierry Besson is affiliated with the University of Rouen in France. Their research primarily focuses on the field of chemistry, with a particular emphasis on organic chemistry. Research topics explored by Besson include quinazolinone synthesis and applications, catalytic C-H functionalization methods, acute lymphoblastic leukemia research, synthesis and biological evaluation, as well as the synthesis and characterization of heterocyclic compounds.

Besson's publication record shows contributions predominantly in the area of synthetic and medicinal chemistry. Frequent publication venues include:

  • Synthesis
  • Pharmaceuticals
  • Molecules
  • Blood
  • Catalysts

Notable recent papers authored or co-authored by Besson include:

  • "Diaryliodoniums Salts as Coupling Partners for Transition-Metal Catalyzed C- and N-Arylation of Heteroarenes," 2020, Catalysts
  • "DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3," 2021, Journal of Clinical Investigation
  • "Review on the Synthesis and Therapeutic Potential of Pyrido[2,3-d], [3,2-d], [3,4-d] and [4,3-d]pyrimidine Derivatives," 2022, Pharmaceuticals
  • "Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity," 2022, Immunology
  • "Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts," 2021, Pharmaceuticals

Throughout their career, Besson has collaborated extensively with several frequent co-authors. These include:

  • Corinne Fruit
  • Alexandra Pacheco-Benichou
  • John D. Crispino
  • Rahul S. Bhansali
  • Gerald Wertheim

Besson's research spans multiple subfields within chemistry, as well as interdisciplinary areas bridging organic chemistry and molecular biology. These subfields include:

  • Organic Chemistry
  • Public Health, Environmental and Occupational Health
  • Molecular Biology
  • Materials Chemistry
  • Immunology

The scientist's work in acute lymphoblastic leukemia reflects an engagement with biomedical research, in addition to fundamental chemical synthesis studies. Their publication topics frequently combine synthesis and biological activity, catalytic reactions, and the evaluation of therapeutic potential in heterocyclic compound development.

Best Publications

  • Gas-Phase Structure of a π-Allyl−Palladium Complex: Efficient Infrared Spectroscopy in a 7 T Fourier Transform Mass Spectrometer

    Joost M. Bakker;Thierry Besson;Joël Lemaire;Debora Scuderi

  • Microwave acceleration of the Pechmann reaction on graphite/montmorillonite K10: application to the preparation of 4-substituted 7-aminocoumarins

    Stéphane Frère;Valérie Thiéry;Thierry Besson

  • A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.

    Séverine Coutadeur;Hélène Benyamine;Laurence Delalonde;Catherine de Oliveira

  • Microwave-assisted Niementowski reaction. Back to the roots

    François-René Alexandre;François-René Alexandre;Amaya Berecibar;Thierry Besson

  • Microwave-assisted synthesis of galacto-oligosaccharides from lactose with immobilized β-galactosidase from Kluyveromyces lactis

    Thierry Maugard;Damian Gaunt;Marie Dominique Legoy;Thierry Besson

  • Microwave radiation can increase the rate of enzyme-catalysed reactions in organic media

    Marie-Claire Parker;Thierry Besson;Sylvain Lamare;Marie-Dominique Legoy

  • Synthesis of novel 5-substituted indirubins as protein kinases inhibitors.

    Anne Beauchard;Yoan Ferandin;Stéphane Frère;Olivier Lozach

  • Synthesis and in vitro antitumour evaluation of benzothiazole-2-carbonitrile derivatives

    Valérie Bénéteau;Thierry Besson;Jérôme Guillard;Stéphane Léonce

  • Influence of microwave irradiation on enzymatic properties: applications in enzyme chemistry

    Barbara Rejasse;Sylvain Lamare;Marie-Dominique Legoy;Thierry Besson

  • Tautomerism of uracil probed via infrared spectroscopy of singly hydrated protonated uracil

    Joost M. Bakker;Rajeev K. Sinha;Thierry Besson;Maurizio Brugnara

  • Novel series of 8H-quinazolino[4,3-b]quinazolin-8-ones via two Niementowski condensations

    François-René Alexandre;François-René Alexandre;Amaya Berecibar;Roger Wrigglesworth;Thierry Besson

  • Stability improvement of immobilized Candida antarctica lipase B in an organic medium under microwave radiation

    Barbara Réjasse;Sylvain Lamare;Marie-Dominique Legoy;Thierry Besson

  • Antimicrobial evaluation of 3,1-benzoxazin-4-ones, 3,1-benzothiazin-4-ones, 4-alkoxyquinazolin-2-carbonitriles and N-arylimino-1,2,3-dithiazoles

    Thierry Besson;Charles W. Rees;Gilles Cottenceau;Anne-Marie Pons

  • Microwave-accelerated Dimroth rearrangement for the synthesis of 4-anilino-6-nitroquinazolines. Application to an efficient synthesis of a microtubule destabilizing agent

    Alicia Foucourt;Carole Dubouilh-Benard;Elizabeth Chosson;Cécile Corbière

  • Multistep synthesis of thiazoloquinazolines under microwave irradiation in solution

    Thierry Besson;Jérôme Guillard;Charles W Rees

  • Expeditious synthesis and cytotoxic activity of new cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines.

    Christelle Lamazzi;Stéphane Léonce;Bruno Pfeiffer;Pierre Renard

  • Influence of microwave radiation on free Candida antarctica lipase B activity and stability.

    Barbara Réjasse;Thierry Besson;Marie-Dominique Legoy;Sylvain Lamare

  • Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: Synthesis, biological evaluation and molecular modeling studies

    Cédric Logé;Alexandra Testard;Valérie Thiéry;Olivier Lozach

  • Synthesis and kinase inhibitory activity of novel substituted indigoids.

    Anne Beauchard;Hélène Laborie;Hervé Rouillard;Olivier Lozach

  • Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3.

    Alexandra Testard;Cédric Logé;Benoît Léger;Jean-Michel Robert

  • Synthesis of latonduine derivatives via intramolecular Heck reaction

    Aurélien Putey;Lionel Joucla;Laurent Picot;Thierry Besson

  • Diaryliodoniums Salts as Coupling Partners for Transition-Metal Catalyzed C- and N-Arylation of Heteroarenes

    Alexandra Pacheco-Benichou;Thierry Besson;Corinne Fruit

Frequent Co-Authors

Gérald Guillaumet
Gérald Guillaumet University of Orléans
Laurent Meijer
Laurent Meijer Perha Pharmaceuticals
John D. Crispino
John D. Crispino Northwestern University
Martin Carroll
Martin Carroll University of Pennsylvania
Christiane Guguen-Guillouzo
Christiane Guguen-Guillouzo University of Rennes
Jean-Michel Léger
Jean-Michel Léger University of Poitiers
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Clara Viñas
Clara Viñas Institut de Ciència de Materials de Barcelona
Yann Herault
Yann Herault Institute of Genetics and Molecular and Cellular Biology
Michael B. Hursthouse
Michael B. Hursthouse University of Southampton

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