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D-Index & Metrics

Molecular Biology

D-Index
64
Citations
26738
World Ranking
1700
National Ranking
858

Overview

Martin Carroll is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on medicine, with significant contributions to biochemistry, genetics, and molecular biology.

The main fields of study for Martin Carroll encompass medicine and biochemistry, genetics, and molecular biology, with notable subfields including hematology, molecular biology, cancer research, oncology, and genetics. Their work notably addresses topics such as acute myeloid leukemia research, cancer genomics and diagnostics, histone deacetylase inhibitors research, protein degradation and inhibitors, acute lymphoblastic leukemia research, myeloproliferative neoplasms diagnosis and treatment, and hematopoietic stem cell transplantation.

Martin Carroll has contributed to several recent papers, including:

  • Single-cell mutation analysis of clonal evolution in myeloid malignancies, 2020, Nature
  • DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation, 2021, Genome Biology
  • Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence, 2021, Cancer Discovery
  • Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging, 2024, Cell
  • Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia, 2021, The Journal of Experimental Medicine

The scientist frequently publishes in notable venues, with the largest body of work appearing in Blood, followed by bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Cancer Discovery, and Leukemia.

Frequent coauthors collaborating with Martin Carroll include Sarah Skuli, Gerald Wertheim, Sarah K. Tasian, Kathrin M. Bernt, and Christian Hurtz.

Best Publications

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

    Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab

  • The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

    Ly P Vu;Brian F Pickering;Yuanming Cheng;Sara Zaccara

  • Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

    Thomas Farge;Thomas Farge;Estelle saland;Estelle saland;Fabienne de Toni;Fabienne de Toni;Nesrine Aroua;Nesrine Aroua

  • ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.

    Omar Abdel-Wahab;Mazhar Adli;Lindsay M. LaFave;Jie Gao

  • Survival of acute myeloid leukemia cells requires PI3 kinase activation

    Qing Xu;Serge Emile Simpson;Timothy J. Scialla;Adam Bagg

  • Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells

    Saar Gill;Sarah K. Tasian;Marco Ruella;Olga Shestova

  • An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells

    Monica L. Guzman;Randall M. Rossi;Sundar Neelakantan;Xiaojie Li

  • Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

    Jean-Emmanuel Sarry;Kathleen Murphy;Robin Perry;Patricia V. Sanchez

  • AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

    Wunderlich M;Chou Fs;Link Ka;Mizukawa B

  • The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-dependent signaling pathways

    M Carroll;M H Tomasson;G F Barker;T R Golub

  • Single-cell mutation analysis of clonal evolution in myeloid malignancies.

    Linde A. Miles;Robert L. Bowman;Tiffany R. Merlinsky;Isabelle S. Csete

  • Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

    Sheng Li;Francine E Garrett-Bakelman;Stephen S Chung;Mathijs A Sanders

  • Distinct IL-2 Receptor Signaling Pattern in CD4+CD25 + Regulatory T Cells

    Steven J. Bensinger;Patrick T. Walsh;Jidong Zhang;Martin Carroll

  • Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR

    Stella Maris Ranuncolo;Jose M Polo;Jamil Dierov;Michael Singer

  • Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

    Elizabeth O. Hexner;Cynthia Serdikoff;Mahfuza Jan;Cezary R. Swider

  • Tribbles homolog 2 inactivates C/EBPα and causes acute myelogenous leukemia

    Karen Keeshan;Yiping He;Bas J. Wouters;Olga Shestova

  • Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

    Duane C. Hassane;Monica L. Guzman;Cheryl Corbett;Xiaojie Li

  • Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.

    Courtney D. DiNardo;Kathleen J. Propert;Alison W. Loren;Elisabeth Paietta

  • mTOR regulates cell survival after etoposide treatment in primary AML cells.

    Unknown

Frequent Co-Authors

David L. Porter
David L. Porter University of Pennsylvania
Ari Melnick
Ari Melnick Cornell University
Ross L. Levine
Ross L. Levine Memorial Sloan Kettering Cancer Center
Adam Bagg
Adam Bagg Hospital of the University of Pennsylvania
Stephan A. Grupp
Stephan A. Grupp Children's Hospital of Philadelphia
Edward A. Stadtmauer
Edward A. Stadtmauer University of Pennsylvania
Christopher E. Mason
Christopher E. Mason Cornell University
Christian Recher
Christian Recher Federal University of Toulouse Midi-Pyrénées
David T. Teachey
David T. Teachey Children's Hospital of Philadelphia
Martin S. Tallman
Martin S. Tallman Northwestern University

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