World's Best Scientists 2026 revealed!
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Biology and Biochemistry
USA
2023

D-Index & Metrics

Chemistry

D-Index
134
Citations
72443
World Ranking
263
National Ranking
127

Biology and Biochemistry

D-Index
141
Citations
77749
World Ranking
261
National Ranking
177

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 2014 - Fellow, National Academy of Inventors
  • 2013 - Promega Biotechnology Research Award, American Society for Microbiology
  • 2010 - Member of the National Academy of Engineering For developing synthetic biology tools to engineer the antimalarial drug artemisinin.
  • 2000 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Jay D. Keasling is affiliated with the University of California, Berkeley in the United States. Their research primarily spans biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, pharmacology, biomedical engineering, plant science, and genetics.

The scientist's work focuses on several main topics, including:

  • Microbial Metabolic Engineering and Bioproduction
  • Microbial Natural Products and Biosynthesis
  • Plant biochemistry and biosynthesis
  • Biofuel production and bioconversion
  • Enzyme Catalysis and Immobilization
  • Fungal and yeast genetics research
  • CRISPR and Genetic Engineering

Keasling has coauthored numerous publications with the following frequent collaborators:

  • Edward E. K. Baidoo (31 publications)
  • Christopher J. Petzold (30 publications)
  • Aindrila Mukhopadhyay (27 publications)
  • Michael K. Jensen (25 publications)
  • Yuzhong Liu (25 publications)

They have published extensively in specific venues including:

  • bioRxiv (Cold Spring Harbor Laboratory), 33 publications
  • Metabolic Engineering, 15 publications
  • ACS Synthetic Biology, 13 publications
  • Nature Communications, 12 publications
  • Applied and Environmental Microbiology, 6 publications

Recent papers associated with or authored by Jay D. Keasling include:

  • A microbial supply chain for production of the anti-cancer drug vinblastine, 2022, Nature
  • Biofuels for a sustainable future, 2021, Cell
  • Microbial production of advanced biofuels, 2021, Nature Reviews Microbiology
  • Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism, 2020, Nature Communications
  • <strong>Memory in Microbes: Quantifying History-Dependent Behavior in a Bacterium</strong>, 2023, OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)

The scientist has been recognized with several awards, including:

  • Fellow of the American Academy of Arts and Sciences, 2016
  • Fellow, National Academy of Inventors, 2014
  • Promega Biotechnology Research Award, American Society for Microbiology, 2013
  • Member of the National Academy of Engineering, 2010 (for developing synthetic biology tools to engineer the antimalarial drug artemisinin)
  • Fellow of the Indian National Academy of Engineering (INAE), 2000

Best Publications

  • Production of the antimalarial drug precursor artemisinic acid in engineered yeast

    Dae-Kyun Ro;Eric M. Paradise;Mario Ouellet;Karl J. Fisher

  • High-level semi-synthetic production of the potent antimalarial artemisinin

    C. J. Paddon;P. J. Westfall;D. J. Pitera;K. Benjamin

  • Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

    Vincent J J Martin;Douglas J Pitera;Sydnor T Withers;Jack D Newman

  • Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

    Eric J. Steen;Yisheng Kang;Gregory Bokinsky;Zhihao Hu

  • Synthetic protein scaffolds provide modular control over metabolic flux

    John E Dueber;Gabriel C Wu;G Reza Malmirchegini;G Reza Malmirchegini;Tae Seok Moon

  • Engineering Cellular Metabolism

    Jens Nielsen;Jens Nielsen;Jens Nielsen;Jay D. Keasling

  • Microbial engineering for the production of advanced biofuels

    Pamela P. Peralta-Yahya;Pamela P. Peralta-Yahya;Fuzhong Zhang;Fuzhong Zhang;Stephen B. del Cardayre;Jay D. Keasling

  • Manufacturing molecules through metabolic engineering.

    Jay D. Keasling

  • Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids.

    Fuzhong Zhang;James M Carothers;Jay D Keasling

  • Precise and reliable gene expression via standard transcription and translation initiation elements

    Vivek K Mutalik;Joao C Guimaraes;Joao C Guimaraes;Guillaume Cambray;Colin Lam

  • Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

    Patrick J. Westfall;Douglas J. Pitera;Jacob R. Lenihan;Diana Eng

  • Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

    Chris J. Paddon;Jay D. Keasling

  • Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels.

    Sung Kuk Lee;Howard Chou;Howard Chou;Howard Chou;Timothy S Ham;Timothy S Ham;Taek Soon Lee;Taek Soon Lee

  • Engineering microbial biofuel tolerance and export using efflux pumps

    Mary J Dunlop;Zain Y Dossani;Zain Y Dossani;Heather L Szmidt;Heather L Szmidt;Hou Cheng Chu;Hou Cheng Chu

  • Complete biosynthesis of cannabinoids and their unnatural analogues in yeast

    Xiaozhou Luo;Michael A. Reiter;Leo d’Espaux;Jeff Wong

  • Identification and microbial production of a terpene-based advanced biofuel

    Pamela P. Peralta-Yahya;Mario Ouellet;Mario Ouellet;Rossana Chan;Rossana Chan;Aindrila Mukhopadhyay;Aindrila Mukhopadhyay

  • Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol

    Eric J Steen;Eric J Steen;Rossana Chan;Rossana Chan;Nilu Prasad;Nilu Prasad;Samuel L. Myers;Samuel L. Myers

  • Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

    Brian F Pfleger;Douglas J Pitera;Christina D Smolke;Christina D Smolke;Jay D Keasling;Jay D Keasling

  • BglBrick vectors and datasheets: A synthetic biology platform for gene expression

    Taek Soon Lee;Taek Soon Lee;Rachel A Krupa;Rachel A Krupa;Fuzhong Zhang;Fuzhong Zhang;Meghdad Hajimorad;Meghdad Hajimorad

  • A microbial supply chain for production of the anti-cancer drug vinblastine

    Unknown

  • Designed divergent evolution of enzyme function.

    Yasuo Yoshikuni;Thomas E. Ferrin;Jay D. Keasling

Frequent Co-Authors

Edward E. K. Baidoo
Edward E. K. Baidoo Lawrence Berkeley National Laboratory
Christopher J. Petzold
Christopher J. Petzold Lawrence Berkeley National Laboratory
Aindrila Mukhopadhyay
Aindrila Mukhopadhyay Lawrence Berkeley National Laboratory
Paul D. Adams
Paul D. Adams Lawrence Berkeley National Laboratory
Taek Soon Lee
Taek Soon Lee Lawrence Berkeley National Laboratory
Adam P. Arkin
Adam P. Arkin Lawrence Berkeley National Laboratory
Blake A. Simmons
Blake A. Simmons Lawrence Berkeley National Laboratory
Henrik Vibe Scheller
Henrik Vibe Scheller Lawrence Berkeley National Laboratory
Seema Singh
Seema Singh Sandia National Laboratories
Yinjie J. Tang
Yinjie J. Tang Washington University in St. Louis

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