World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
104
Citations
36092
World Ranking
1268
National Ranking
746

Research.com Recognitions

  • 2012 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Huimin Zhao is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a total of 381 publications in these areas. Zhao's work spans multiple subfields including molecular biology, organic chemistry, biomedical engineering, pharmacology, and plant science.

Much of Zhao's research centers on topics such as microbial metabolic engineering and bioproduction, CRISPR and genetic engineering, enzyme catalysis and immobilization, biofuel production and bioconversion, RNA and protein synthesis mechanisms, microbial natural products and biosynthesis, and genomics and phylogenetic studies.

Frequent collaborators in Zhao's work include Ee Lui Ang, Yifeng Wei, Nilmani Singh, Vinh Tran, and Zia Fatma. Over the course of their career, Zhao has published extensively in several scientific venues. Notable publication outlets with multiple contributions include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, ACS Synthetic Biology, ACS Catalysis, and Metabolic Engineering.

Some of their recent papers are:

  • Directed Evolution: Methodologies and Applications, 2021, Chemical Reviews
  • Photoenzymatic enantioselective intermolecular radical hydroalkylation, 2020, Nature
  • Enzyme function prediction using contrastive learning, 2023, Science
  • Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation, 2021, Nature Structural & Molecular Biology
  • Photobiocatalysis for Abiological Transformations, 2022, Accounts of Chemical Research

Zhao has been recognized by several scientific organizations. They were named a Fellow of the John Simon Guggenheim Memorial Foundation in 2012 and a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • Chromatin architecture reorganization during stem cell differentiation

    Jesse R. Dixon;Inkyung Jung;Siddarth Selvaraj;Yin Shen

  • Molecular evolution by staggered extension process (StEP) in vitro recombination

    Huimin Zhao;Lori Giver;Zhixin Shao;Joseph A. Affholter

  • DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

    Zengyi Shao;Hua Zhao;Huimin Zhao

  • High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system.

    Ryan E. Cobb;Yajie Wang;Huimin Zhao

  • Recent developments in pyridine nucleotide regeneration.

    Wilfred A van der Donk;Huimin Zhao

  • DIRECTED EVOLUTION CONVERTS SUBTILISIN E INTO A FUNCTIONAL EQUIVALENT OF THERMITASE

    Huimin Zhao;Frances H. Arnold

  • Regeneration of cofactors for use in biocatalysis

    Huimin Zhao;Wilfred Adrianus van der Donk

  • Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae

    Zehua Bao;Han Xiao;Jing Liang;Lu Zhang

  • A Rewritable, Random-Access DNA-Based Storage System.

    S. M. Hossein Tabatabaei Yazdi;Yongbo Yuan;Jian Ma;Huimin Zhao

  • Optimization of DNA shuffling for high fidelity recombination.

    Huimin Zhao;Frances H. Arnold

  • Directed Evolution: Methodologies and Applications.

    Yajie Wang;Pu Xue;Mingfeng Cao;Tianhao Yu

  • Random-priming in vitro recombination: An effective tool for directed evolution

    Zhixin Shao;Huimin Zhao;Lori Giver;Frances H. Arnold

  • Transcription activator‐like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing

    Ning Sun;Huimin Zhao

  • Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering.

    Wenjuan Zha;Sheryl B. Rubin-Pitel;Zengyi Shao;Huimin Zhao

  • Selective elimination of mitochondrial mutations in the germline by genome editing

    Pradeep Reddy;Alejandro Ocampo;Keiichiro Suzuki;Jinping Luo

  • Directed evolution of enzymes and biosynthetic pathways.

    Tyler W. Johannes;Huimin Zhao

  • Engineering microbial factories for synthesis of value-added products.

    Jing Du;Zengyi Shao;Huimin Zhao

  • CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters

    Mingzi M Zhang;Fong Tian Wong;Yajie Wang;Shangwen Luo

  • Design and construction of acetyl-CoA overproducing Saccharomyces cerevisiae strains

    Jiazhang Lian;Tong Si;Nikhil U. Nair;Huimin Zhao

  • Yeast Surface Display of Trifunctional Minicellulosomes for Simultaneous Saccharification and Fermentation of Cellulose to Ethanol

    Fei Wen;Jie Sun;Jie Sun;Huimin Zhao

Frequent Co-Authors

Wilfred A. van der Donk
Wilfred A. van der Donk University of Illinois at Urbana-Champaign
Frances H. Arnold
Frances H. Arnold California Institute of Technology
Jung-Kul Lee
Jung-Kul Lee Konkuk University
Satish K. Nair
Satish K. Nair University of Illinois at Urbana-Champaign
William W. Metcalf
William W. Metcalf University of Illinois at Urbana-Champaign
Bing Ren
Bing Ren New York Genome Center
John F. Hartwig
John F. Hartwig University of California, Berkeley
Olgica Milenkovic
Olgica Milenkovic University of Illinois at Urbana-Champaign
Yong Su Jin
Yong Su Jin University of Illinois at Urbana-Champaign
Susannah L. Scott
Susannah L. Scott University of California, Santa Barbara

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