World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
16297
World Ranking
7068
National Ranking
3247

Research.com Recognitions

  • 2016 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Mattheos A. G. Koffas is affiliated with Rensselaer Polytechnic Institute in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a notable emphasis on Molecular Biology within that domain. The scientist's work spans several subfields, including Pharmacology, Oceanography, Astronomy and Astrophysics, and Nuclear and High Energy Physics.

The main topics of Mattheos A. G. Koffas's research include:

  • Microbial Metabolic Engineering and Bioproduction
  • Geophysics and Gravity Measurements
  • Ionosphere and Magnetosphere Dynamics
  • Astrophysics and Cosmic Phenomena
  • Plant Biochemistry and Biosynthesis
  • Microbial Natural Products and Biosynthesis
  • Biofuel Production and Bioconversion

The scientist has contributed to a range of frequent publication venues such as:

  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
  • Current Opinion in Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbial Cell Factories
  • Metabolic Engineering

Recent publications by Mattheos A. G. Koffas include:

  • "Application of combinatorial optimization strategies in synthetic biology", 2020, Nature Communications
  • "Phytostilbenes as agrochemicals: biosynthesis, bioactivity, metabolic engineering and biotechnology", 2020, Natural Product Reports
  • "Microbial Coculture for Flavonoid Synthesis", 2020, Trends in biotechnology
  • "De novo biosynthesis of complex natural product sakuranetin using modular co-culture engineering", 2020, Applied Microbiology and Biotechnology
  • "Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae", 2020, Biotechnology for Biofuels

The scientist frequently collaborates with the following co-authors:

  • Jennifer Hurley
  • Jian Zha
  • Robert J. Linhardt
  • Jin-Song Shi
  • Zhenghong Xu

Mattheos A. G. Koffas was awarded the title of Fellow of the Indian National Academy of Engineering (INAE) in 2016.

Best Publications

  • Metabolic Burden: Cornerstones in Synthetic Biology and Metabolic Engineering Applications

    Gang Wu;Qiang Yan;J. Andrew Jones;Yinjie J. Tang

  • Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

    Peng Xu;Lingyun Li;Fuming Zhang;Gregory Stephanopoulos

  • Modular optimization of multi-gene pathways for fatty acids production in E. coli

    Peng Xu;Qin Gu;Wenya Wang;Wenya Wang;Lynn Wong

  • Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA.

    Peng Xu;Sridhar Ranganathan;Zachary L. Fowler;Costas D. Maranas

  • Optimization of a heterologous pathway for the production of flavonoids from glucose

    Christine Nicole S. Santos;Mattheos Koffas;Gregory Stephanopoulos

  • Engineering Central Metabolic Pathways for High-Level Flavonoid Production in Escherichia coli

    Effendi Leonard;Kok-Hong Lim;Phan-Nee Saw;Mattheos A. G. Koffas

  • Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids.

    Effendi Leonard;Yajun Yan;Zachary L. Fowler;Zhen Li

  • High-Yield Resveratrol Production in Engineered Escherichia coli

    Chin Giaw Lim;Zachary L. Fowler;Thomas Hueller;Steffen Schaffer

  • ePathBrick: A Synthetic Biology Platform for Engineering Metabolic Pathways in E. coli

    Peng Xu;Amerin Vansiri;Namita Bhan;Mattheos A. G. Koffas

  • Microbial production of natural and non-natural flavonoids: Pathway engineering, directed evolution and systems/synthetic biology.

    Ramesh Prasad Pandey;Prakash Parajuli;Mattheos A.G. Koffas;Jae Kyung Sohng

  • Biosynthesis of Natural Flavanones in Saccharomyces cerevisiae

    Yajun Yan;Abhijeet Kohli;Mattheos A. G. Koffas

  • Experimental and computational optimization of an Escherichia coli co-culture for the efficient production of flavonoids.

    J. Andrew Jones;Victoria R. Vernacchio;Andrew L. Sinkoe;Shannon M. Collins

  • Masquerading microbial pathogens: Capsular polysaccharides mimic host-tissue molecules

    Brady F. Cress;Jacob A. Englaender;Wenqin He;Dennis Kasper

  • Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production.

    Zachary L. Fowler;William W. Gikandi;Mattheos A. G. Koffas

  • Metabolic engineering for plant natural product biosynthesis in microbes

    Joseph A Chemler;Mattheos A G Koffas

  • Improving NADPH availability for natural product biosynthesis in Escherichia coli by metabolic engineering.

    Joseph A. Chemler;Zachary L. Fowler;Kyle P. McHugh;Mattheos A.G. Koffas

  • Engineering microbial consortia by division of labor

    Garrett W. Roell;Jian Zha;Rhiannon R. Carr;Mattheos A. Koffas

  • Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli.

    Effendi Leonard;Yajun Yan;Mattheos A.G. Koffas

  • Metabolic pathway balancing and its role in the production of biofuels and chemicals

    J Andrew Jones;Ö Duhan Toparlak;Mattheos A G Koffas

  • Biosynthesis and biotechnological production of flavanones: current state and perspectives.

    Zachary L. Fowler;Mattheos A. G. Koffas

Frequent Co-Authors

Robert J. Linhardt
Robert J. Linhardt Rensselaer Polytechnic Institute
Peng Xu
Peng Xu Chinese Academy of Sciences
Yajun Yan
Yajun Yan University of Georgia
Jonathan S. Dordick
Jonathan S. Dordick Rensselaer Polytechnic Institute
Fuming Zhang
Fuming Zhang Rensselaer Polytechnic Institute
Richard A. Gross
Richard A. Gross Rensselaer Polytechnic Institute
Yinjie J. Tang
Yinjie J. Tang Washington University in St. Louis
Qipeng Yuan
Qipeng Yuan Beijing University of Chemical Technology
Costas D. Maranas
Costas D. Maranas Pennsylvania State University

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