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Biology and Biochemistry
Korea
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
156
Citations
85924
World Ranking
144
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2025 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2023 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2022 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2017 - Member of the National Academy of Sciences
  • 2017 - Fellow, National Academy of Inventors
  • 2013 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2013 - Fellow, The World Academy of Sciences
  • 2010 - Member of the National Academy of Engineering For leadership in bacterial biotechnology and metabolic engineering, including development of fermentation processes for biodegradable polymers and organic acids.
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Sang Yup Lee is affiliated with the Korea Advanced Institute of Science and Technology in South Korea. Their research domain encompasses biochemistry, genetics, and molecular biology, with a substantial focus on molecular biology and biomedical engineering. Their work also extends into pharmacology, biomaterials, and computer vision and pattern recognition.

The scientist's primary research topics include microbial metabolic engineering and bioproduction, biofuel production and bioconversion, enzyme catalysis and immobilization, CRISPR and genetic engineering, microbial natural products and biosynthesis, biodegradable polymer synthesis and properties, and mechanisms of RNA and protein synthesis.

Their recent publications, illustrating a range of scientific interests, include:

  • MEMOTE for standardized genome-scale metabolic model testing, 2020, Nature Biotechnology
  • Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production, 2020, Chemical Society Reviews
  • Metabolic Engineering of Escherichia coli for Natural Product Biosynthesis, 2020, Trends in Biotechnology
  • Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase, 2020, Nature Communications
  • Designing Microbial Cell Factories for the Production of Chemicals, 2022, JACS Au

Frequent collaborators of Sang Yup Lee include:

  • Gi Bae Kim
  • Hyun Uk Kim
  • Kyeong Rok Choi
  • Jong An Lee
  • Dongsoo Yang

The principal venues where their work has been published are:

  • Proceedings of the National Academy of Sciences
  • Nature Communications
  • Metabolic Engineering
  • Current Opinion in Biotechnology
  • Trends in Biotechnology

Awards received by Sang Yup Lee include:

  • Member of the National Academy of Sciences (2017)
  • Fellow, National Academy of Inventors (2017)
  • Fellow, The World Academy of Sciences (2013)
  • Fellow of the Indian National Academy of Engineering (INAE) (2013)
  • Member of the National Academy of Engineering (2010) for leadership in bacterial biotechnology and metabolic engineering, including development of fermentation processes for biodegradable polymers and organic acids
  • Fellow of the American Association for the Advancement of Science (AAAS) (2006)

Best Publications

  • antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

    Kai Blin;Simon Shaw;Katharina Steinke;Rasmus Villebro

  • antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

    Tilmann Weber;Kai Blin;Srikanth Duddela;Daniel Krug

  • Fermentative butanol production by clostridia

    Sang Yup Lee;Jin Hwan Park;Seh Hee Jang;Lars K. Nielsen

  • Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

    Harry Yim;Robert Haselbeck;Wei Niu;Catherine Pujol-Baxley

  • antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.

    Kai Blin;Thomas Wolf;Marc G. Chevrette;Xiaowen Lu

  • High cell-density culture of Escherichia coli

    Sang Yup Lee

  • Production of succinic acid by bacterial fermentation

    Hyohak Song;Sang Yup Lee

  • Secretory and extracellular production of recombinant proteins using Escherichia coli

    JH Choi;SangYup Lee

  • Systems metabolic engineering of microorganisms for natural and non-natural chemicals

    Jeong Wook Lee;Dokyun Na;Jong Myoung Park;Joungmin Lee

  • Plastic bacteria? Progress and prospects for polyhydroxyalkanoate production in bacteria

    Sang Yup Lee

  • Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation

    Seongjoon Joo;In Jin Cho;Hogyun Seo;Hyeoncheol Francis Son

  • Microbial cell-surface display.

    Sang Yup Lee;Jong Hyun Choi;Zhaohui Xu

  • Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs

    Dokyun Na;Seung Min Yoo;Hannah Chung;Hyegwon Park

  • Metabolic engineering of Escherichia coli for the production of l-valine based on transcriptome analysis and in silico gene knockout simulation

    Jin Hwan Park;Kwang Ho Lee;Tae Yong Kim;Sang Yup Lee

  • Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber

    Xiao-Xia Xia;Zhi-Gang Qian;Chang Seok Ki;Young Hwan Park

  • Process analysis and economic evaluation for Poly(3-hydroxybutyrate) production by fermentation

    Jong-il Choi;Sang Yup Lee

  • Factors affecting the economics of polyhydroxyalkanoate production by bacterial fermentation

    J Choi;SangYup Lee

  • Systems strategies for developing industrial microbial strains.

    Sang Yup Lee;Hyun Uk Kim;Hyun Uk Kim

  • Current status and applications of genome-scale metabolic models.

    Changdai Gu;Gi Bae Kim;Won Jun Kim;Hyun Uk Kim

  • Optical Biosensors for the Detection of Pathogenic Microorganisms

    Seung Min Yoo;Sang Yup Lee

Frequent Co-Authors

Hyun Uk Kim
Hyun Uk Kim Korea Advanced Institute of Science and Technology
Tae Jung Park
Tae Jung Park Chung-Ang University
Si Jae Park
Si Jae Park Ewha Womans University
Ho Nam Chang
Ho Nam Chang Korea Advanced Institute of Science and Technology
Dong-Yup Lee
Dong-Yup Lee Sungkyunkwan University
Yang-Kyu Choi
Yang-Kyu Choi Korea Advanced Institute of Science and Technology
Won Hi Hong
Won Hi Hong Korea Advanced Institute of Science and Technology
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Jae-Hyuk Ahn
Jae-Hyuk Ahn Chungnam National University
Bongsoo Kim
Bongsoo Kim Pusan National University

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