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Genetics

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Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2012 - Promega Biotechnology Research Award, American Society for Microbiology
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2006 - Member of the National Academy of Engineering For scholarship, technological advances, and entrepreneurial activities in metabolic engineering.
  • 1996 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Bernhard O. Palsson is affiliated with the University of California, San Diego in the United States. Their research output spans biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, genetics, pharmacology, infectious diseases, and biomedical engineering.

The scientist's work covers key topics including microbial metabolic engineering and bioproduction, genomics and phylogenetic studies, bacterial genetics and biotechnology, RNA and protein synthesis mechanisms, gene regulatory network analysis, microbial natural products and biosynthesis, and evolution and genetic dynamics.

Some recent papers by Bernhard O. Palsson include:

  • MEMOTE for standardized genome-scale metabolic model testing, 2020, Nature Biotechnology
  • An atlas of human metabolism, 2020, Science Signaling
  • Reconstructing organisms in silico: genome-scale models and their emerging applications, 2020, Nature Reviews Microbiology
  • SBML Level 3: an extensible format for the exchange and reuse of biological models, 2020, Molecular Systems Biology
  • Mini review: Genome mining approaches for the identification of secondary metabolite biosynthetic gene clusters in Streptomyces, 2020, Computational and Structural Biotechnology Journal

Frequent co-authors of Bernhard O. Palsson include:

  • Richard Szubin
  • Anand V. Sastry
  • Jonathan M. Monk
  • Adam M. Feist
  • Kevin Rychel

Throughout their career, Palsson has published extensively in journals such as bioRxiv (Cold Spring Harbor Laboratory), mSystems, Nucleic Acids Research, Nature Communications, and the Proceedings of the National Academy of Sciences.

Honors awarded include:

  • Promega Biotechnology Research Award, American Society for Microbiology, 2012
  • Fellow of the American Association for the Advancement of Science (AAAS), 2010
  • Member of the National Academy of Engineering, 2006, for scholarship, technological advances, and entrepreneurial activities in metabolic engineering
  • Fellow of the Indian National Academy of Engineering (INAE), 1996

Best Publications

  • Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

    Mingxun Wang;Jeremy J Carver;Vanessa V Phelan;Laura M Sanchez

  • A protocol for generating a high-quality genome-scale metabolic reconstruction.

    Ines Thiele;Ines Thiele;Bernhard Ø Palsson

  • Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

    Jan Schellenberger;Richard Que;Ronan M T Fleming;Ines Thiele

  • A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.

    Adam M Feist;Christopher S Henry;Jennifer L Reed;Markus Krummenacker

  • Global reconstruction of the human metabolic network based on genomic and bibliomic data

    Natalie C. Duarte;Scott A. Becker;Neema Jamshidi;Ines Thiele

  • Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network

    Jochen Förster;Iman Famili;Patrick Fu;Bernhard Ø. Palsson

  • An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

    Jennifer L Reed;Thuy D Vo;Christophe H Schilling;Bernhard O Palsson

  • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110.

    Amit Varma;B. O. Palsson

  • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

    Jeremy S. Edwards;Jeremy S. Edwards;Rafael U. Ibarra;Bernhard O. Palsson

  • Genome-scale models of microbial cells: evaluating the consequences of constraints

    Nathan D. Price;Jennifer L. Reed;Bernhard Ø. Palsson

  • A comprehensive genome‐scale reconstruction of Escherichia coli metabolism—2011

    Jeffrey D Orth;Tom M Conrad;Jessica Na;Joshua A Lerman

  • A community-driven global reconstruction of human metabolism

    Ines Thiele;Neil Swainston;Ronan M T Fleming;Andreas Hoppe

  • The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities

    J. S. Edwards;B. O. Palsson

  • Metabolic Flux Balancing: Basic Concepts, Scientific and Practical Use

    Amit Varma;Bernhard O. Palsson

  • Systems Biology: Properties of Reconstructed Networks

    Bernhard O. Palsson

  • Reconstruction of biochemical networks in microorganisms

    Adam M. Feist;Markus J. Herrgård;Ines Thiele;Jennie L. Reed

  • Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth

    Rafael U. Ibarra;Jeremy S. Edwards;Bernhard O. Palsson

  • Integrating high-throughput and computational data elucidates bacterial networks

    Markus W. Covert;Eric M. Knight;Jennifer L. Reed;Markus J. Herrgard

  • Applications of genome-scale metabolic reconstructions

    Matthew A Oberhardt;Bernhard Ø Palsson;Jason A Papin

  • Cancer cell lines

    John R. W. Masters;Bernhard Palsson

Frequent Co-Authors

Adam M. Feist
Adam M. Feist University of California, San Diego
Byung-Kwan Cho
Byung-Kwan Cho Korea Advanced Institute of Science and Technology
Nathan E. Lewis
Nathan E. Lewis University of California, San Diego
Ines Thiele
Ines Thiele University of Galway
Gyun Min Lee
Gyun Min Lee Korea Advanced Institute of Science and Technology
Jens Nielsen
Jens Nielsen Chalmers University of Technology
Ronan M. T. Fleming
Ronan M. T. Fleming Leiden University
Stephen G. Emerson
Stephen G. Emerson Columbia University
Nathan D. Price
Nathan D. Price University of Illinois at Urbana-Champaign
Karsten Zengler
Karsten Zengler University of California, San Diego

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