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Biology and Biochemistry

D-Index
81
Citations
22385
World Ranking
3918
National Ranking
93

Overview

Lars K. Nielsen is affiliated with the University of Queensland in Australia. Their research focuses on fields within Biochemistry, Genetics, and Molecular Biology, with particular emphasis on molecular biology and biomedical engineering. They have contributed extensively to topics such as microbial metabolic engineering and bioproduction, viral infectious diseases and gene expression in insects, biofuel production and bioconversion, metabolomics and mass spectrometry studies, gene regulatory network analysis, bioinformatics and genomic networks, and virus-based gene therapy research.

The scientist has been published frequently in venues including bioRxiv (Cold Spring Harbor Laboratory), Biotechnology and Bioengineering, Metabolic Engineering, ACS Synthetic Biology, and arXiv (Cornell University).

Among their recent papers are:

  • MEMOTE for standardized genome-scale metabolic model testing, 2020, Nature Biotechnology
  • Enhancing CO2-Valorization Using Clostridium autoethanogenum for Sustainable Fuel and Chemicals Production, 2020, Frontiers in Bioengineering and Biotechnology
  • Redox controls metabolic robustness in the gas-fermenting acetogen Clostridium autoethanogenum, 2020, Proceedings of the National Academy of Sciences
  • What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines, 2020, Metabolic Engineering
  • Model-guided dynamic control of essential metabolic nodes boosts acetyl-coenzyme A-dependent bioproduction in rewired Pseudomonas putida, 2021, Metabolic Engineering

The scientist often collaborates with peers such as Esteban Marcellin, Kaspar Valgepea, Teddy Groves, Igor Marín de Mas, and Nicholas Luke Cowie.

Best Publications

  • Fermentative butanol production by clostridia

    Sang Yup Lee;Jin Hwan Park;Seh Hee Jang;Lars K. Nielsen

  • Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types.

    Jens M. Kelm;Jens M. Kelm;Nicholas E. Timmins;Catherine J. Brown;Martin Fussenegger

  • Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals

    Kate L. Ormerod;David L. A. Wood;Nancy Lachner;Shaan L. Gellatly

  • MEMOTE for standardized genome-scale metabolic model testing

    Christian Lieven;Moritz Emanuel Beber;Brett G. Olivier;Frank T. Bergmann

  • Microbial hyaluronic acid production

    Barrie Fong Chong;Lars M. Blank;Richard Mclaughlin;Lars K. Nielsen

  • Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

    Richard J. Mills;Drew M. Titmarsh;Xaver Koenig;Xaver Koenig;Benjamin L. Parker

  • AraGEM, a Genome-Scale Reconstruction of the Primary Metabolic Network in Arabidopsis

    Cristiana Gomes de Oliveira Dal'Molin;Lake-Ee Quek;Robin William Palfreyman;Stevens Michael Brumbley

  • Towards quantitative metabolomics of mammalian cells: development of a metabolite extraction protocol.

    Stefanie Dietmair;Nicholas E. Timmins;Peter P. Gray;Lars K. Nielsen

  • An analysis of therapist treatment effects: Toward providing feedback to individual therapists on their clients' psychotherapy outcome

    John C. Okiishi;Michael J. Lambert;Dennis Eggett;Lars Nielsen

  • Recon 2.2: from reconstruction to model of human metabolism

    Neil Swainston;Kieran Smallbone;Hooman Hefzi;Paul D. Dobson

  • OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis.

    Lake-Ee Quek;Christoph Wittmann;Lars K Nielsen;Jens O Krömer

  • Molecular Composition of IMP1 Ribonucleoprotein Granules

    Lars Jønson;Jonas Vikesaa;Anders Krogh;Lars K Nielsen

  • An environmental life cycle assessment comparing Australian sugarcane with US corn and UK sugar beet as producers of sugars for fermentation.

    M. A. Renouf;M. K. Wegener;L. K. Nielsen

  • Generation of Multicellular Tumor Spheroids by the Hanging-Drop Method

    Nicholas E. Timmins;Lars K. Nielsen

  • Metabolic flux analysis in mammalian cell culture.

    Lake-Ee Quek;Stefanie Dietmair;Jens O. Krömer;Lars K. Nielsen

  • Metabolic and practical considerations on microbial electrosynthesis

    Korneel Rabaey;Peter R. Girguis;Lars K Nielsen

  • Microbial Propionic Acid Production

    R. Axayacatl Gonzalez-Garcia;Tim McCubbin;Laura Navone;Chris Stowers

  • A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

    Hooman Hefzi;Kok Siong Ang;Michael Hanscho;Aarash Bordbar

  • Genome-wide discovery of human splicing branchpoints

    Tim R. Mercer;Tim R. Mercer;Michael B. Clark;Michael B. Clark;Stacey B. Andersen;Marion E. Brunck

  • Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus.

    Kashif Sheikh;Jochen Förster;Lars K. Nielsen

Frequent Co-Authors

Tim R. Mercer
Tim R. Mercer Garvan Institute of Medical Research
John S. Mattick
John S. Mattick University of New South Wales
Nathan E. Lewis
Nathan E. Lewis University of California, San Diego
Dong-Yup Lee
Dong-Yup Lee Sungkyunkwan University
Lars M. Blank
Lars M. Blank RWTH Aachen University
Sang Yup Lee
Sang Yup Lee Korea Advanced Institute of Science and Technology
Marcel E. Dinger
Marcel E. Dinger University of Sydney
Jens Nielsen
Jens Nielsen Chalmers University of Technology
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Ryan J. Taft
Ryan J. Taft Illumina (United States)

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