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Genetics

D-Index
64
Citations
14646
World Ranking
2795
National Ranking
1225

Overview

Ryan J. Taft is affiliated with Illumina in the United States and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work spans multiple subfields including genetics, molecular biology, pathology and forensic medicine, clinical biochemistry, and cancer research.

The scientist's research focuses primarily on genomics and rare diseases. Other main topics include genomic variations and chromosomal abnormalities, genetic factors in colorectal cancer, RNA modifications and cancer, metabolism and genetic disorders, cancer genomics and diagnostics, and BRCA gene mutations in cancer.

Ryan J. Taft has published in several prominent venues, notably:

  • Genetics in Medicine Open
  • Genetics in Medicine
  • npj Genomic Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Genetics and Metabolism

Frequent co-authors include Denise Perry, Erin Thorpe, Adeline Vanderver, Alison J. Coffey, and Alka Malhotra. The collaborations with these researchers indicate a networked approach across multiple disciplines and topics relevant to genetics and genomics.

Several recent publications illustrate the scope of Taft's work:

  • ExpansionHunter Denovo: a computational method for locating known and novel repeat expansions in short-read sequencing data, 2020, Genome Biology
  • Effect of Whole-Genome Sequencing on the Clinical Management of Acutely Ill Infants With Suspected Genetic Disease, 2021, JAMA Pediatrics
  • Best practices for the analytical validation of clinical whole-genome sequencing intended for the diagnosis of germline disease, 2020, npj Genomic Medicine
  • Spinal muscular atrophy diagnosis and carrier screening from genome sequencing data, 2020, Genetics in Medicine
  • Best practices for the interpretation and reporting of clinical whole genome sequencing, 2022, npj Genomic Medicine

Best Publications

  • Non‐coding RNAs: regulators of disease

    Ryan J Taft;Ken C Pang;Timothy R Mercer;Marcel Dinger

  • The relationship between non-protein-coding DNA and eukaryotic complexity.

    Ryan J. Taft;Michael Pheasant;John S. Mattick

  • The reality of pervasive transcription

    Michael B. Clark;Paulo P. Amaral;Felix J. Schlesinger;Marcel E. Dinger

  • Small RNAs derived from snoRNAs

    Ryan J. Taft;Evgeny A. Glazov;Timo Lassmann;Yoshihide Hayashizaki

  • The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

    Harukazu Suzuki;Alistair R.R. Forrest;Erik Van Nimwegen;Carsten O. Daub

  • The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.

    Guy Barry;J. A. Briggs;D. P. Vanichkina;E. M. Poth

  • Tiny RNAs associated with transcription start sites in animals.

    Ryan J Taft;Evgeny A Glazov;Nicole Cloonan;Cas Simons

  • Detection of long repeat expansions from PCR-free whole-genome sequence data.

    Egor Dolzhenko;Joke J.F.A. van Vugt;Richard J. Shaw;Mitchell A. Bekritsky

  • A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

    Alessandro Guffanti;Michele Iacono;Paride Pelucchi;Namshin Kim;Namshin Kim

  • A global view of genomic information--moving beyond the gene and the master regulator.

    John S. Mattick;Ryan J. Taft;Geoffrey J. Faulkner

  • ExpansionHunter: A sequence-graph based tool to analyze variation in short tandem repeat regions.

    Egor Dolzhenko;Viraj Deshpande;Felix Schlesinger;Peter Krusche

  • Dynamic isomiR regulation in Drosophila development

    Selene L. Fernandez-Valverde;Ryan J. Taft;John S. Mattick

  • Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.

    Sueli Marques;David van Bruggen;Darya Pavlovna Vanichkina;Darya Pavlovna Vanichkina;Elisa Mariagrazia Floriddia

  • MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

    Selene L. Fernandez-Valverde;Ryan J. Taft;John S. Mattick

  • Genome-wide discovery of human splicing branchpoints

    Tim R. Mercer;Tim R. Mercer;Michael B. Clark;Michael B. Clark;Stacey B. Andersen;Marion E. Brunck

  • A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

    Cas Simons;Nicole I. Wolf;Nathan McNeil;Ljubica Caldovic

  • Mutations in DARS Cause Hypomyelination with Brain Stem and Spinal Cord Involvement and Leg Spasticity

    Ryan J. Taft;Adeline Vanderver;Richard J. Leventer;Stephen A. Damiani

  • Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

    Ryan J Taft;Cas Simons;Satu Nahkuri;Harald Oey

  • A clinical approach to the diagnosis of patients with leukodystrophies and genetic leukoencephelopathies

    Sumit Parikh;Geneviève Bernard;Richard J. Leventer;Marjo S. van der Knaap

  • Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

    Tim R Mercer;Michael B Clark;Joanna Crawford;Marion E Brunck

Frequent Co-Authors

John S. Mattick
John S. Mattick University of New South Wales
Sean M. Grimmond
Sean M. Grimmond University of Melbourne
Marcel E. Dinger
Marcel E. Dinger University of Sydney
Tim R. Mercer
Tim R. Mercer Garvan Institute of Medical Research
Noriko Miyake
Noriko Miyake Yokohama City University
Timo Lassmann
Timo Lassmann Telethon Kids Institute
Geoffrey J. Faulkner
Geoffrey J. Faulkner University of Queensland

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