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D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
23779
World Ranking
3338
National Ranking
1685

Research.com Recognitions

  • 2008 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Costas D. Maranas is affiliated with Pennsylvania State University in the United States. Their research spans the field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology, Biomedical Engineering, Infectious Diseases, Computational Theory and Mathematics, and Animal Science and Zoology.

The scientist's main topics of work include:

  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion
  • Enzyme Catalysis and Immobilization
  • SARS-CoV-2 and COVID-19 Research
  • Gene Regulatory Network Analysis
  • Animal Virus Infections Studies
  • Computational Drug Discovery Methods

Frequent co-authors in their publications include Veda Sheersh Boorla, Ratul Chowdhury, Hoang V. Dinh, Patrick F. Suthers, and Debolina Sarkar.

Costas D. Maranas has contributed extensively to various publication venues. The most frequent among these are:

  • bioRxiv (Cold Spring Harbor Laboratory) with 20 publications
  • Metabolic Engineering with 12 publications
  • Viruses with 3 publications
  • PLoS Computational Biology with 3 publications
  • ACS Synthetic Biology with 3 publications

Selected recent publications include:

  • "Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer", 2022, Proceedings of the National Academy of Sciences
  • "Toward low-cost biological and hybrid biological/catalytic conversion of cellulosic biomass to fuels", 2022, Energy & Environmental Science
  • "Bacterial colonization reprograms the neonatal gut metabolome", 2020, Nature Microbiology
  • "Mitochondrial ATP generation is more proteome efficient than glycolysis", 2024, Nature Chemical Biology
  • "Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2", 2021, Proceedings of the National Academy of Sciences

Among awards, Costas D. Maranas was recognized as a Fellow of the Indian National Academy of Engineering (INAE) in 2008.

Best Publications

  • OptKnock: A Bilevel Programming Framework for Identifying Gene Knockout Strategies for Microbial Strain Optimization

    Anthony P. Burgard;Priti Pharkya;Costas D. Maranas

  • Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

    Laurent Heirendt;Sylvain Arreckx;Thomas Pfau;Sebastián N. Mendoza

  • αBB: A global optimization method for general constrained nonconvex problems

    Ioannis P. Androulakis;Costas D. Maranas;Christodoulos A. Floudas

  • OptStrain: A computational framework for redesign of microbial production systems

    Priti Pharkya;Anthony P. Burgard;Costas D. Maranas

  • Flux Coupling Analysis of Genome-Scale Metabolic Network Reconstructions

    Anthony P. Burgard;Evgeni V. Nikolaev;Christophe H. Schilling;Costas D. Maranas

  • OptForce: An Optimization Procedure for Identifying All Genetic Manipulations Leading to Targeted Overproductions

    Sridhar Ranganathan;Patrick F. Suthers;Costas D. Maranas

  • In silico design and adaptive evolution of Escherichia coli for production of lactic acid.

    Stephen S. Fong;Anthony P. Burgard;Christopher D. Herring;Eric M. Knight

  • OptCom: a multi-level optimization framework for the metabolic modeling and analysis of microbial communities.

    Ali R. Zomorrodi;Costas D. Maranas

  • Optimization based automated curation of metabolic reconstructions

    Vinay Satish Kumar;Madhukar S Dasika;Costas D Maranas

  • An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems.

    Priti Pharkya;Costas D. Maranas

  • Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA.

    Peng Xu;Sridhar Ranganathan;Zachary L. Fowler;Costas D. Maranas

  • Synthetic biology of cyanobacteria: unique challenges and opportunities

    Bertram M. Berla;Rajib Saha;Cheryl M. Immethun;Costas D. Maranas

  • Optimization-based framework for inferring and testing hypothesized metabolic objective functions.

    Anthony P. Burgard;Costas D. Maranas

  • Finding all solutions of nonlinearly constrained systems of equations

    Costas D. Maranas;Christodoulos A. Floudas

  • Global optimization in generalized geometric programming

    Costas D. Maranas;Christodoulos A. Floudas

  • Creating multiple-crossover DNA libraries independent of sequence identity

    Stefan Lutz;Marc Ostermeier;Gregory L. Moore;Costas D. Maranas

  • GrowMatch: an automated method for reconciling in silico/in vivo growth predictions.

    Vinay Satish Kumar;Costas D. Maranas

  • Zea mays iRS1563: a comprehensive genome-scale metabolic reconstruction of maize metabolism.

    Rajib Saha;Patrick F. Suthers;Costas D. Maranas

  • A genome-scale Escherichia coli kinetic metabolic model k-ecoli457 satisfying flux data for multiple mutant strains

    Ali Khodayari;Costas D. Maranas

  • Multiperiod Planning and Scheduling of Multiproduct Batch Plants under Demand Uncertainty

    Spas B. Petkov;Costas D. Maranas

Frequent Co-Authors

Himadri B. Pakrasi
Himadri B. Pakrasi Washington University in St. Louis
Christodoulos A. Floudas
Christodoulos A. Floudas Texas A&M University
James G. Ferry
James G. Ferry Pennsylvania State University
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Lee R. Lynd
Lee R. Lynd Dartmouth College
Brian F. Pfleger
Brian F. Pfleger University of Wisconsin–Madison
Thomas K. Wood
Thomas K. Wood Pennsylvania State University
Eleftherios T. Papoutsakis
Eleftherios T. Papoutsakis University of Delaware
Stephen J. Benkovic
Stephen J. Benkovic Pennsylvania State University
Bertrand Hirel
Bertrand Hirel INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement

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