World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
14958
World Ranking
8709
National Ranking
155

Research.com Recognitions

  • 2009 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Vassily Hatzimanikatis is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research primarily lies within the domain of Biochemistry, Genetics, and Molecular Biology, supported by an extensive publication record with 250 works in this area. Subfields of focus include Molecular Biology, Biomedical Engineering, Computational Theory and Mathematics, Pharmacology, and Genetics.

Their research topics cover a range of subjects related to microbial and metabolic systems, including Microbial Metabolic Engineering and Bioproduction, Metabolomics and Mass Spectrometry Studies, Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks, Viral Infectious Diseases and Gene Expression in Insects, Computational Drug Discovery Methods, and Biofuel production and bioconversion.

Recent significant publications by Hatzimanikatis and collaborators include:

  • MEMOTE for standardized genome-scale metabolic model testing, 2020, Nature Biotechnology
  • Metabolic interaction models recapitulate leaf microbiota ecology, 2023, Science
  • Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism, 2020, Cell Host & Microbe
  • The ETFL formulation allows multi-omics integration in thermodynamics-compliant metabolism and expression models, 2020, Nature Communications
  • A genome-scale metabolic model of Saccharomyces cerevisiae that integrates expression constraints and reaction thermodynamics, 2021, Nature Communications

Frequent co-authors with whom Hatzimanikatis has collaborated extensively include Ljubiša Mišković, Hameri Tuure, Georgios Fengos, Meriç Ataman, and María Masid.

The main venues for their publications are:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Metabolic Engineering

Hatzimanikatis was awarded the title of Fellow of the Indian National Academy of Engineering (INAE) in 2009.

Best Publications

  • A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.

    Adam M Feist;Christopher S Henry;Jennifer L Reed;Markus Krummenacker

  • Thermodynamics-Based Metabolic Flux Analysis

    Christopher S. Henry;Linda J. Broadbelt;Vassily Hatzimanikatis

  • MEMOTE for standardized genome-scale metabolic model testing

    Christian Lieven;Moritz Emanuel Beber;Brett G. Olivier;Frank T. Bergmann

  • Group Contribution Method for Thermodynamic Analysis of Complex Metabolic Networks

    Matthew D. Jankowski;Christopher S. Henry;Linda J. Broadbelt;Vassily Hatzimanikatis

  • Exploring the diversity of complex metabolic networks

    Vassily Hatzimanikatis;Chunhui Li;Justin A. Ionita;Christopher S. Henry

  • Metabolic flux analysis of hybridoma cells in different culture media using mass balances.

    H.P.J. Bonarius;V. Hatzimanikatis;K.P.H. Meesters;C.D. de Gooijer

  • Metabolic fluxes in riboflavin-producing Bacillus subtilis

    Uwe Sauer;Vassily Hatzimanikatis;James E. Bailey;Michel Hochuli

  • Kinetic models in industrial biotechnology - Improving cell factory performance.

    Joachim Almquist;Marija Cvijovic;Vassily Hatzimanikatis;Jens Nielsen

  • Genome-Scale Thermodynamic Analysis of Escherichia coli Metabolism

    Christopher S. Henry;Matthew D. Jankowski;Linda J. Broadbelt;Vassily Hatzimanikatis

  • Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes

    James E. Bailey;Adriana Sburlati;Vassily Hatzimanikatis;Kelvin Lee

  • Physiology and metabolic fluxes of wild-type and riboflavin-producing Bacillus subtilis.

    U. Sauer;V. Hatzimanikatis;H.-P. Hohmann;M. Manneberg

  • Fremgangsmater for fremstilling av utvalgte organiske produkter ved hjelp av mikroorganismer med crabtree-negativ fenotype, anvendelse av mikroorgansimene for fremstilling av melkesyre og K. thermotolerans gjaerstamme.

    Kolstad Jeffrey John;Eyal Aharon Meir;Carlson Ting Liu;Starr John N

  • Discovery and analysis of novel metabolic pathways for the biosynthesis of industrial chemicals: 3-hydroxypropanoate

    Christopher S. Henry;Linda J. Broadbelt;Vassily Hatzimanikatis;Vassily Hatzimanikatis

  • Metabolic Control Analysis under Uncertainty: Framework Development and Case Studies

    Liqing Wang;Inanç Birol;Vassily Hatzimanikatis

  • Towards kinetic modeling of genome‐scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiological constraints

    Anirikh Chakrabarti;Anirikh Chakrabarti;Ljubisa Miskovic;Ljubisa Miskovic;Keng Cher Soh;Keng Cher Soh;Vassily Hatzimanikatis;Vassily Hatzimanikatis

  • Analysis and design of metabolic reaction networks via mixed‐integer linear optimization

    Vassily Hatzimanikatis;Christodoulos A. Floudas;James E. Bailey

  • Dynamical analysis of gene networks requires both mRNA and protein expression information

    Vassily Hatzimanikatis;Kelvin H. Lee

  • ATLAS of Biochemistry: A Repository of All Possible Biochemical Reactions for Synthetic Biology and Metabolic Engineering Studies.

    Noushin Hadadi;Jasmin Hafner;Adrian Shajkofci;Aikaterini Zisaki

  • Insights into the relation between mRNA and protein expression patterns: I. Theoretical considerations.

    Amit Mehra;Kelvin H. Lee;Vassily Hatzimanikatis

  • Proteomics: Theoretical and Experimental Considerations

    Vassily Hatzimanikatis;Leila H. Choe;Kelvin H. Lee

Frequent Co-Authors

Linda J. Broadbelt
Linda J. Broadbelt Northwestern University
Jens Nielsen
Jens Nielsen Chalmers University of Technology
Kelvin H. Lee
Kelvin H. Lee University of Delaware
Lars M. Blank
Lars M. Blank RWTH Aachen University
Adam M. Feist
Adam M. Feist University of California, San Diego
Sang Yup Lee
Sang Yup Lee Korea Advanced Institute of Science and Technology
Dominique Soldati-Favre
Dominique Soldati-Favre University of Geneva
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Costas Panayiotou
Costas Panayiotou Aristotle University of Thessaloniki

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in studying Biology and Biochemistry, there are several growing online career paths to consider. For those who want to advance in healthcare management, an affordable online MBA healthcare management degree can open doors in administration, operations, and leadership roles. This option is ideal for graduates aiming to combine scientific knowledge with business acumen.

Exploring the technical side of healthcare, many students branch into the world of medical coding and billing. Understanding the certified coding specialist certification is important, as it can affect your career prospects, salary, and day-to-day responsibilities within medical settings.

When deciding if this path suits you, it helps to know what is medical coding salary and the typical training involved. Finally, weigh the is medical coding a good career pros and cons, including job stability, remote work options, and the need for strong attention to detail. Each of these avenues offers a unique way to leverage your background in biology or biochemistry while building a rewarding career in the healthcare industry.

Best Scientists Citing Vassily Hatzimanikatis

Trending Scientists

Recently Published Articles