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Biology and Biochemistry

D-Index
62
Citations
20020
World Ranking
10571
National Ranking
4593

Overview

Michelle A. Lowes is affiliated with Rockefeller University in the United States. Their research predominantly lies within the field of Medicine, with significant contributions to Dermatology, Surgery, and Epidemiology. Additional work touches on Molecular Biology and Public Health, Environmental and Occupational Health.

The scientist's publication record focuses heavily on dermatological conditions, particularly Hidradenitis Suppurativa and its treatments. Main research topics include:

  • Hidradenitis Suppurativa and Treatments
  • Colorectal and Anal Carcinomas
  • Microscopic Colitis
  • Anorectal Disease Treatments and Outcomes
  • Chemotherapy-related skin toxicity
  • Autoimmune and Inflammatory Disorders
  • Inflammasome and immune disorders

Frequent co-authors collaborating with Michelle A. Lowes include:

  • Afsáneh Alavi
  • Haley B. Naik
  • Noah Goldfarb
  • Joslyn S. Kirby
  • John W. Frew

Publications by Michelle A. Lowes are found in key dermatology and medical journals. Frequent publication venues include:

  • Journal of the American Academy of Dermatology
  • British Journal of Dermatology
  • JAMA Dermatology
  • Journal of Investigative Dermatology
  • International Journal of Women's Dermatology

Recent papers authored or co-authored by Michelle A. Lowes cover various aspects of dermatology, particularly related to Hidradenitis Suppurativa. Notable examples include:

  • Comorbidity screening in hidradenitis suppurativa: Evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations (2021), Journal of the American Academy of Dermatology
  • What causes hidradenitis suppurativa?-15 years after (2020), Experimental Dermatology
  • A Systematic Review of Promising Therapeutic Targets in Hidradenitis Suppurativa: A Critical Evaluation of Mechanistic and Clinical Relevance (2020), Journal of Investigative Dermatology
  • Pain management in hidradenitis suppurativa and a proposed treatment algorithm (2020), Journal of the American Academy of Dermatology
  • Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis (2023), Journal of Allergy and Clinical Immunology

Best Publications

  • Pathogenesis and therapy of psoriasis

    Michelle A. Lowes;Anne M. Bowcock;James G. Krueger

  • Immunology of Psoriasis

    Michelle A Lowes;Mayte Suárez-Fariñas;James G Krueger

  • Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.

    Michelle A. Lowes;Toyoko Kikuchi;Judilyn Fuentes-Duculan;Irma Cardinale

  • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

    K.E. Nograles;L.C. Zaba;E. Guttman-Yassky;J. Fuentes-Duculan

  • Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses.

    Lisa C. Zaba;Irma Cardinale;Patricia Gilleaudeau;Mary Sullivan-Whalen

  • Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

    Michelle A. Lowes;Francesca Chamian;Maria Veronica Abello;Judilyn Fuentes-Duculan

  • Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell polarizing myeloid dendritic cells

    Lisa C. Zaba;Judilyn Fuentes-Duculan;Narat John Eungdamrong;Maria Veronica Abello

  • The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

    Michelle A. Lowes;Chris B. Russell;David A. Martin;Jennifer E. Towne

  • PSORS2 Is Due to Mutations in CARD14

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Katherine C. Pierson

  • TNF Inhibition Rapidly Down-Regulates Multiple Proinflammatory Pathways in Psoriasis Plaques

    Alice B. Gottlieb;Francesca Chamian;Salman Masud;Irma Cardinale

  • Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Shenghui Duan

  • Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis

    Emma Guttman-Yassky;Michelle A. Lowes;Judilyn Fuentes-Duculan;Lisa C. Zaba

  • Resident and "inflammatory" dendritic cells in human skin.

    Lisa C. Zaba;James G. Krueger;Michelle A. Lowes

  • Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

    Lisa C. Zaba;Judilyn Fuentes-Duculan;Ralph M. Steinman;James G. Krueger

  • A subpopulation of CD163-positive macrophages is classically activated in psoriasis.

    Judilyn Fuentes-Duculan;Mayte Suárez-Fariñas;Lisa C. Zaba;Kristine E. Nograles

  • Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not “immediate-response” TNF genes

    Lisa C. Zaba;Mayte Suárez-Fariñas;Judilyn Fuentes-Duculan;Kristine E. Nograles

  • North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management.

    Ali Alikhan;Christopher Sayed;Afsaneh Alavi;Raed Alhusayen

  • North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management

    Ali Alikhan;Christopher Sayed;Afsaneh Alavi;Raed Alhusayen

  • Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis

    Emma Guttman-Yassky;Michelle A. Lowes;Judilyn Fuentes-Duculan;Julia Whynot

  • Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

    Francesca Chamian;Michelle A. Lowes;Shao-Lee Lin;Edmund Lee

Frequent Co-Authors

James G. Krueger
James G. Krueger Rockefeller University
Mayte Suárez-Fariñas
Mayte Suárez-Fariñas Icahn School of Medicine at Mount Sinai
Judilyn Fuentes-Duculan
Judilyn Fuentes-Duculan Rockefeller University
Raphaela Goldbach-Mansky
Raphaela Goldbach-Mansky National Institute of Allergy and Infectious Diseases
Anne M. Bowcock
Anne M. Bowcock Icahn School of Medicine at Mount Sinai
Emma Guttman-Yassky
Emma Guttman-Yassky Icahn School of Medicine at Mount Sinai
Gregor B. E. Jemec
Gregor B. E. Jemec University of Copenhagen
Alexa B. Kimball
Alexa B. Kimball Beth Israel Deaconess Medical Center
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School
Glenda M. Halliday
Glenda M. Halliday University of Sydney

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