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Genetics

D-Index
99
Citations
33705
World Ranking
783
National Ranking
391

Medicine

D-Index
101
Citations
35583
World Ranking
8020
National Ranking
4165

Research.com Recognitions

  • 1941 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James T. Elder is affiliated with the University of Michigan-Ann Arbor in the United States. The primary areas of research include Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these fields, specific subfields of study focus on Immunology, Genetics, Dermatology, Oncology, and Physiology.

The main topics covered in their work center around Psoriasis: Treatment and Pathogenesis, T-cell and B-cell Immunology, Cytokine Signaling Pathways and Interactions, Dermatology and Skin Diseases, Asthma and respiratory diseases, Genetic Associations and Epidemiology, and Cancer-related molecular mechanisms research.

Recent publications include:

  • "Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis," 2023, Nature Communications
  • "A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response," 2021, Nature Genetics
  • "Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies," 2021, Journal of Allergy and Clinical Immunology
  • "Alcohol consumption and smoking in relation to psoriasis: a Mendelian randomization study," 2022, British Journal of Dermatology
  • "Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and Mendelian randomisation study," 2020, Annals of the Rheumatic Diseases

Frequent co-authors collaborating with James T. Elder include Lam C. Tsoi, Philip E. Stuart, Rajan P. Nair, Matthew T. Patrick, and Jóhann E. Guðjónsson.

The most common publication venues for their work are as follows:

  • Journal of Investigative Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Genetics
  • British Journal of Dermatology

James T. Elder was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1941.

Best Publications

  • Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

    Rajan P. Nair;Kristina Callis Duffin;Cynthia Helms;Jun Ding

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    David Ellinghaus;Luke Jostins;Sarah L. Spain;Adrian Cortes

  • Sequence and Haplotype Analysis Supports HLA-C as the Psoriasis Susceptibility 1 Gene

    Rajan P. Nair;Philip E. Stuart;Ioana Nistor;Ravi Hiremagalore

  • Overexpression of transforming growth factor α in psoriatic epidermis

    James T. Elder;Gary J. Fisher;Patricia B. Lindquist;Gregory L. Bennett

  • Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

    Rafael De Cid;Eva Riveira-Munoz;Patrick L.J.M. Zeeuwen;Jason Robarge

  • Pervasive sharing of genetic effects in autoimmune disease.

    Chris Cotsapas;Benjamin F. Voight;Benjamin F. Voight;Elizabeth Rossin;Kasper Lage;Kasper Lage;Kasper Lage

  • Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

    B. J. Nickoloff;G. D. Karabin;J. N. W. N. Barker;C. E. M. Griffiths

  • Induction of IL-17+ T Cell Trafficking and Development by IFN-γ: Mechanism and Pathological Relevance in Psoriasis

    Ilona Kryczek;Allen T. Bruce;Johann E. Gudjonsson;Andrew Johnston

  • Evidence for Two Psoriasis Susceptibility Loci (HLA and 17q) and Two Novel Candidate Regions (16q and 20p) by Genome-Wide Scan

    Rajan P. Nair;Tilo Henseler;Stefan Jenisch;Philip Stuart

  • A developmentally stable chromatin structure in the human β-globin gene cluster

    William C. Forrester;Craig Thompson;J. T. Elder;Mark Groudine

  • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

    Eva Ellinghaus;David Ellinghaus;Philip E Stuart;Rajan P Nair

  • Application of Retinol to Human Skin In Vivo Induces Epidermal Hyperplasia and Cellular Retinoid Binding Proteins Characteristic of Retinoic Acid but Without Measurable Retinoic Acid Levels or Irritation

    Sewon Kang;Elizabeth A. Duell;Gary J. Fisher;Subhash C. Datta

  • Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

    David Ellinghaus;Eva Ellinghaus;Rajan P. Nair;Philip E. Stuart

  • Genome-wide association analysis identifies three psoriasis susceptibility loci

    Philip E Stuart;Rajan P Nair;Eva Ellinghaus;Jun Ding

  • Association analyses identify six new psoriasis susceptibility loci in the Chinese population

    Liang-Dan Sun;Hui Cheng;Hui Cheng;Zai-Xing Wang;Zai-Xing Wang;An-Ping Zhang;An-Ping Zhang

  • Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.

    Bingshan Li;Bingshan Li;Lam C. Tsoi;William R. Swindell;Johann E. Gudjonsson

  • Molecular dissection of psoriasis: integrating genetics and biology.

    James T. Elder;Allen T. Bruce;Johann E. Gudjonsson;Andrew Johnston

  • Pervasive Sharing of Genetic Effects in Autoimmune Disease

    Chris Cotsapas;Benjamin F. Voight;Elizabeth Rossin;Kasper Lage

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    L. C. Tsoi;S. L. Spain;J. Knight;E. Ellinghaus

Frequent Co-Authors

Rajan P. Nair
Rajan P. Nair University of Michigan–Ann Arbor
John J. Voorhees
John J. Voorhees University of Michigan–Ann Arbor
Philip E. Stuart
Philip E. Stuart University of Michigan–Ann Arbor
Lam C. Tsoi
Lam C. Tsoi University of Michigan–Ann Arbor
Johann E. Gudjonsson
Johann E. Gudjonsson University of Michigan–Ann Arbor
Andrew Johnston
Andrew Johnston University of Michigan–Ann Arbor
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Andre Franke
Andre Franke Kiel University
Enno Christophers
Enno Christophers Kiel University
Gary J. Fisher
Gary J. Fisher University of Michigan–Ann Arbor

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