His main research concerns Genetics, Psoriasis, Genetic association, Allele and Immunology. Psoriasis is a subfield of Dermatology that he investigates. His Genetic association research incorporates elements of Exome sequencing, Genetic variability, Genetic variation and Human genetic variation.
His work focuses on many connections between Allele and other disciplines, such as Major histocompatibility complex, that overlap with his field of interest in Identity by descent, Genetic linkage, Genotype, Genetic marker and Interleukin 12 receptor, beta 1 subunit. His Immunology research focuses on subjects like Missense mutation, which are linked to Generalized pustular psoriasis, Nonsynonymous substitution, Compound heterozygosity, Interleukin 36 receptor antagonist and Proinflammatory cytokine. Jonathan Barker interconnects Autoimmune disease, Genomics, 1000 Genomes Project, Computational biology and Genetic architecture in the investigation of issues within Genome-wide association study.
The scientist’s investigation covers issues in Psoriasis, Immunology, Dermatology, Genetics and Internal medicine. His research investigates the connection between Psoriasis and topics such as Adalimumab that intersect with problems in Etanercept. Many of his studies involve connections with topics such as Gene and Immunology.
His studies in Single-nucleotide polymorphism, Allele, Locus, Genome-wide association study and Genetic association are all subfields of Genetics research. In his research on the topic of Locus, Candidate gene is strongly related with Linkage disequilibrium. His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology and Surgery.
His primary areas of investigation include Psoriasis, Internal medicine, Immunology, Psoriasis Area and Severity Index and Dermatology. His Psoriasis study combines topics in areas such as Odds ratio, Adalimumab, Disease, Atopic dermatitis and Cohort. His Disease study integrates concerns from other disciplines, such as Gene expression, Bioinformatics, Immune system, Genetic association and Receptor antagonist.
His study explores the link between Internal medicine and topics such as Oncology that cross with problems in Propensity score weighting and Biologic therapies. His Immunology study combines topics from a wide range of disciplines, such as Schizophrenia, Genome-wide association study and Transporter. His research in Acne tackles topics such as Pathogenesis which are related to areas like Genetics.
Jonathan Barker spends much of his time researching Psoriasis, Internal medicine, Psoriasis Area and Severity Index, Cohort and Genetic association. His Psoriasis research integrates issues from Intensive care medicine, Epidemiology, Disease and Atopic dermatitis. His work deals with themes such as Generalized pustular psoriasis, Immune system, Immunology and Pustular psoriasis, which intersect with Disease.
His work investigates the relationship between Cohort and topics such as Therapeutic drug monitoring that intersect with problems in Observational study, Dosing, Cohort study, Confidence interval and Prospective cohort study. To a larger extent, Jonathan Barker studies Genetics with the aim of understanding Genetic association. His Genome-wide association study research focuses on Schizophrenia and how it connects with Candidate gene, Attention deficit hyperactivity disorder, Tourette syndrome and Linkage disequilibrium.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A global reference for human genetic variation.
Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin.
(2015)
Mechanisms of Disease: Psoriasis.
Frank O. Nestle;Daniel H. Kaplan;Jonathan Barker.
The New England Journal of Medicine (2009)
Pathogenesis and clinical features of psoriasis.
Christopher E. M. Griffiths;Jonathan N. W. N. Barker.
The Lancet (2007)
A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1
Amy Strange;Francesca Capon;Chris C A Spencer.
Nature Genetics (2010)
A global reference for human genetic variation
Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin.
(2015)
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus.
Nature Genetics (2012)
European S3-guidelines on the systemic treatment of psoriasis vulgaris
D Pathirana;AD Ormerod;P Saiag;Catherine Smith.
Journal of The European Academy of Dermatology and Venereology (2009)
Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions
Batya B. Davidovici;Naveed Sattar;Prinz C. Jörg;Luis Puig.
Journal of Investigative Dermatology (2010)
Identification of a Major Susceptibility Locus on Chromosome 6p and Evidence for Further Disease Loci Revealed by a Two Stage Genome-Wide Search in Psoriasis
Richard C. Trembath;R. Lee Clough;Jane L. Rosbotham;Jane L. Rosbotham;Andrew B. Jones.
web science (1997)
British Association of Dermatologists’ guidelines for biologic interventions for psoriasis 2009
C.H. Smith;Alexander Vincent Anstey;J. N. W. N. Barker;A. D. Burden.
British Journal of Dermatology (2009)
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