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Biology and Biochemistry

D-Index
57
Citations
12914
World Ranking
13737
National Ranking
1073

Overview

Francesca Capon is affiliated with King's College London in the United Kingdom. Their research primarily spans Medicine and Immunology and Microbiology, with a focus on immunology, physiology, dermatology, oncology, and rheumatology. The main topics of their work include psoriasis treatment and pathogenesis, asthma and respiratory diseases, dermatology and skin diseases, cytokine signaling pathways and interactions, IL-33, ST2, and ILC pathways, COVID-19 and mental health, and autoimmune bullous skin diseases.

Capon's publication record includes work in several well-regarded scientific journals. Frequent publication venues include the British Journal of Dermatology with 14 publications, bioRxiv (Cold Spring Harbor Laboratory) with 9, Journal of Investigative Dermatology with 9, Journal of Allergy and Clinical Immunology with 3, and Experimental Dermatology with 3 publications. Their body of work spans topics relating largely to dermatology and immunology.

Recent notable papers include:

  • Factors associated with adverse COVID-19 outcomes in patients with psoriasis-insights from a global registry-based study, 2020, Journal of Allergy and Clinical Immunology
  • Psoriasis and Genetics, 2020, Acta Dermato Venereologica
  • Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease, 2020, The American Journal of Human Genetics
  • Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockade, 2024, Nature Communications
  • Single-cell analysis implicates TH17-to-TH2 cell plasticity in the pathogenesis of palmoplantar pustulosis, 2022, Journal of Allergy and Clinical Immunology

Frequent collaborators of Francesca Capon include Catherine Smith, Juliet N. Barker, Richard B. Warren, Satveer K. Mahil, and C.E.M. Griffiths, with collaboration counts ranging from 26 to 41 joint publications.

Their research addresses complex immune and dermatological diseases, with a strong focus on psoriasis and its underlying pathogenesis and treatment mechanisms, particularly involving cytokine signaling pathways and immune cell plasticity.

Best Publications

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Mandibuloacral Dysplasia Is Caused by a Mutation in LMNA-Encoding Lamin A/C

    Giuseppe Novelli;Antoine Muchir;Federica Sangiuolo;Anne Helbling-Leclerc

  • Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

    Alexandros Onoufriadis;Michael A. Simpson;Andrew E. Pink;Paola Di Meglio

  • Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis

    Francesca Capon;Paola Di Meglio;Joanna Szaub;Natalie J. Prescott

  • European Consensus Statement on Phenotypes of Pustular Psoriasis

    A.A. Navarini;D. Burden;Francesca Capon;U. Mrowietz

  • A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups

    Francesca Capon;Michael H. Allen;Mahreen Ameen;A. David Burden

  • The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans.

    Paola Di Meglio;Antonella Di Cesare;Antonella Di Cesare;Ute Laggner;Chung-Ching Chu

  • Searching for Psoriasis Susceptibility Genes in Italy: Genome Scan and Evidence for a New Locus on Chromosome 1

    Francesca Capon;Giuseppe Novelli;Sabrina Semprini;Maurizio Clementi

  • Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene

    Francesca Capon;Marie José Bijlmakers;Natalie Wolf;Maria Quaranta

  • Update on psoriasis immunopathogenesis and targeted immunotherapy

    Satveer K. Mahil;Francesca Capon;Jonathan N. Barker

  • Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients.

    M. Gennarelli;M. Lucarelli;F. Capon;A. Pizzuti

  • Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

    Karen A. Hunt;Vanisha Mistry;Nicholas A. Bockett;Tariq Ahmad

  • Clinical and genetic differences between pustular psoriasis subtypes

    Sophie Twelves;Alshimaa Mostafa;Alshimaa Mostafa;Nick Dand;Elias Burri

  • Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus

    Kati Asumalahti;Colin Veal;Tarja Laitinen;Sari Suomela

  • Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Eva Ellinghaus;Philip E. Stuart

  • The Genetic Basis of Psoriasis

    Francesca Capon

  • Searching for the Major Histocompatibility Complex Psoriasis Susceptibility Gene

    Francesca Capon;Margo Munro;Jonathan Barker;Richard Trembath

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    L. C. Tsoi;S. L. Spain;J. Knight;E. Ellinghaus

Frequent Co-Authors

Richard C. Trembath
Richard C. Trembath King's College London
Jonathan Barker
Jonathan Barker King's College London
Catherine Smith
Catherine Smith King's College London
Giuseppe Novelli
Giuseppe Novelli University of Rome Tor Vergata
Bruno Dallapiccola
Bruno Dallapiccola Bambino Gesù Children's Hospital
Christopher E.M. Griffiths
Christopher E.M. Griffiths University of Manchester
Frank O. Nestle
Frank O. Nestle Deerfield (United States)
Paola Di Meglio
Paola Di Meglio King's College London
Michael A. Simpson
Michael A. Simpson King's College London
Alan D. Irvine
Alan D. Irvine Trinity College Dublin

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