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Genetics

D-Index
65
Citations
20344
World Ranking
2671
National Ranking
1175

Overview

Rajan P. Nair is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with notable contributions in several related subfields including Immunology, Rheumatology, Oncology, Dermatology, and Physiology.

The scientist's main topics of focus cover a range of immunological and dermatological conditions, particularly centered on psoriasis and related diseases. Specific research themes include:

  • Psoriasis: Treatment and Pathogenesis
  • Cytokine Signaling Pathways and Interactions
  • Asthma and respiratory diseases
  • Rheumatoid Arthritis Research and Therapies
  • Dermatology and Skin Diseases
  • Spondyloarthritis Studies and Treatments
  • T-cell and B-cell Immunology

Their scholarly output includes numerous publications across respected journals and venues. Frequent publishing venues consist of:

  • Journal of Investigative Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • Human Genetics and Genomics Advances
  • Nature Communications

Representative recent papers authored or co-authored by Rajan P. Nair include:

  • Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and Mendelian randomisation study (2020, Annals of the Rheumatic Diseases)
  • Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide (2021, Human Genetics and Genomics Advances)
  • Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis (2020, Journal of Investigative Dermatology)
  • Quantifying Differences in Heritability among Psoriatic Arthritis (PsA), Cutaneous Psoriasis (PsC) and Psoriasis vulgaris (PsV) (2020, Scientific Reports)
  • GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets (2023, bioRxiv)

The scientist frequently collaborates with other researchers. Notable co-authors include:

  • James T. Elder
  • Lam C. Tsoi
  • Philip E. Stuart
  • Matthew T. Patrick
  • Trilokraj Tejasvi

Best Publications

  • Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

    Rajan P. Nair;Kristina Callis Duffin;Cynthia Helms;Jun Ding

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA.

    John B. Lowe;Lloyd M. Stoolman;Rajan P. Nair;Robert D. Larsen

  • Sequence and Haplotype Analysis Supports HLA-C as the Psoriasis Susceptibility 1 Gene

    Rajan P. Nair;Philip E. Stuart;Ioana Nistor;Ravi Hiremagalore

  • Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

    Rafael De Cid;Eva Riveira-Munoz;Patrick L.J.M. Zeeuwen;Jason Robarge

  • A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

    Jolanta F. Kukowska-Latallo;Robert D. Larsen;Rajan P. Nair;John B. Lowe

  • Evidence for Two Psoriasis Susceptibility Loci (HLA and 17q) and Two Novel Candidate Regions (16q and 20p) by Genome-Wide Scan

    Rajan P. Nair;Tilo Henseler;Stefan Jenisch;Philip Stuart

  • Molecular cloning, sequence, and expression of a human GDP-L-fucose:. beta. -D-galactoside 2-. alpha. -L-fucosyltransferase cDNA that can form the H blood group antigen

    Robert D. Larsen;Linda K. Ernst;Rajan P. Nair;John B. Lowe;John B. Lowe

  • Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.

    Brent W. Weston;Rajan P. Nair;Robert D. Larsen;John B. Lowe

  • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

    Eva Ellinghaus;David Ellinghaus;Philip E Stuart;Rajan P Nair

  • Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

    David Ellinghaus;Eva Ellinghaus;Rajan P. Nair;Philip E. Stuart

  • Genome-wide association analysis identifies three psoriasis susceptibility loci

    Philip E Stuart;Rajan P Nair;Eva Ellinghaus;Jun Ding

  • Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Shenghui Duan

  • Association analyses identify six new psoriasis susceptibility loci in the Chinese population

    Liang-Dan Sun;Hui Cheng;Hui Cheng;Zai-Xing Wang;Zai-Xing Wang;An-Ping Zhang;An-Ping Zhang

  • Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.

    Bingshan Li;Bingshan Li;Lam C. Tsoi;William R. Swindell;Johann E. Gudjonsson

  • Molecular dissection of psoriasis: integrating genetics and biology.

    James T. Elder;Allen T. Bruce;Johann E. Gudjonsson;Andrew Johnston

  • Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.

    J.B. Lowe;J.F. Kukowska-Latallo;R.P. Nair;R.D. Larsen

  • Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis

    Rajan P. Nair;Andreas Ruether;Philip E. Stuart;Stefan Jenisch

  • Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.

    Rajan P. Nair;Philip Stuart;Tilo Henseler;Stefan Jenisch

  • The genetics of psoriasis.

    James T. Elder;Rajan P. Nair;Sun Wei Guo;Tilo Henseler

Frequent Co-Authors

James T. Elder
James T. Elder University of Michigan–Ann Arbor
Philip E. Stuart
Philip E. Stuart University of Michigan–Ann Arbor
John J. Voorhees
John J. Voorhees University of Michigan–Ann Arbor
Lam C. Tsoi
Lam C. Tsoi University of Michigan–Ann Arbor
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Enno Christophers
Enno Christophers Kiel University
Johann E. Gudjonsson
Johann E. Gudjonsson University of Michigan–Ann Arbor
Andre Franke
Andre Franke Kiel University
Dafna D. Gladman
Dafna D. Gladman Toronto Western Hospital
Anne M. Bowcock
Anne M. Bowcock Icahn School of Medicine at Mount Sinai

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