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Immunology

D-Index
124
Citations
52042
World Ranking
300
National Ranking
189

Medicine

D-Index
124
Citations
52282
World Ranking
3241
National Ranking
1786

Overview

John B. Harley is affiliated with the United States Department of Veterans Affairs in the United States. Their main field of study is Medicine, with a strong focus on Rheumatology, Immunology, and Genetics. Additional subfields include Pathology and Forensic Medicine as well as Surgery.

Their research covers topics such as Systemic Lupus Erythematosus Research, T-cell and B-cell Immunology, Genetic Associations and Epidemiology, Lymphoma Diagnosis and Treatment, Celiac Disease Research and Management, Monoclonal and Polyclonal Antibodies Research, and Immune Cell Function and Interaction.

John B. Harley has contributed to multiple scientific publications with some of their recent papers including:

  • Complement genes contribute sex-biased vulnerability in diverse disorders (2020, Nature)
  • Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus (2020, Annals of the Rheumatic Diseases)
  • Global discovery of lupus genetic risk variant allelic enhancer activity (2021, Nature Communications)
  • Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus (2020, The Journal of Rheumatology)
  • Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles (2021, Arthritis & Rheumatology)

The frequent coauthors of John B. Harley are:

  • Judith A. James (8 shared publications)
  • Kenneth M. Kaufman (7 shared publications)
  • Matthew T. Weirauch (7 shared publications)
  • Viktoryia Laurynenka (6 shared publications)
  • Leah C. Kottyan (6 shared publications)

John B. Harley publishes often in several key venues, including:

  • Arthritis & Rheumatology (3 publications)
  • Frontiers in Lupus (3 publications)
  • Annals of the Rheumatic Diseases (2 publications)
  • Frontiers in Immunology (2 publications)
  • UNC Libraries (2 publications)

Best Publications

  • Development of autoantibodies before the clinical onset of systemic lupus erythematosus.

    Melissa R Arbuckle;Micah T McClain;Mark V Rubertone;R Hal Scofield

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • NIH conference. The idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations.

    Anthony S. Fauci;John B. Harley;William C. Roberts;Victor J. Ferrans

  • A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

    Ludmila Prokunina;Casimiro Castillejo-López;Fredrik Öberg;Iva Gunnarsson

  • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

    Biola M. Javierre;Agustin F. Fernandez;Julia Richter;Fatima Al-Shahrour

  • The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

    Omri Gottesman;Helena Kuivaniemi;Gerard Tromp;W. Andrew Faucett

  • An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus.

    J. A. James;K. M. Kaufman;A. D. Farris;E. Taylor-Albert

  • High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus.

    T B Niewold;J Hua;T J A Lehman;J B Harley

  • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

    Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  • Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees

    Kathy L. Moser;Barbara R. Neas;Barbara R. Neas;Jane E. Salmon;Hua Yu

  • Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry.

    Micah T McClain;Latisha D Heinlen;Latisha D Heinlen;Gregory J Dennis;Jon Roebuck

  • A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

    Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley

  • Systemic lupus erythematosus in adults is associated with previous Epstein‐Barr virus exposure

    Judith A. James;Barbara R. Neas;Kathy L. Moser;Teresa Hall

  • The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

    Shu Zhu;Wen Pan;Xinyang Song;Yan Liu

  • Recent insights into the genetic basis of systemic lupus erythematosus.

    Kathy L. Moser;Jennifer A. Kelly;Christopher J. Lessard;Christopher J. Lessard;John B. Harley;John B. Harley;John B. Harley

  • Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome

    R. Hal Scofield;R. Hal Scofield;R. Hal Scofield;Gail R. Bruner;Bahram Namjou;Robert P. Kimberly

  • Anti-Ro (SS-A) and anti-La (SS-B) in patients with Sjögren's syndrome.

    John B. Harley;Elaine L. Alexander;Wilma B. Bias;Owen F. Fox

  • Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity

    John B. Harley;Xiaoting Chen;Mario Pujato;Daniel Miller

  • The PTPN22 C1858T functional polymorphism and autoimmune diseases—a meta-analysis

    Young Ho Lee;Y. H. Rho;S. J. Choi;J. D. Ji

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity.

    J A James;T Gross;R H Scofield;J B Harley

Frequent Co-Authors

Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Kathy L. Moser
Kathy L. Moser Oklahoma Medical Research Foundation
Timothy J. Vyse
Timothy J. Vyse King's College London

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